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COMSAE Phase 1 Form 116 EXAM QUESTIONS AND CORRECT VERIFIED SOLUTIONS LATEST UPDATE THIS YEAR – JUST RELEASED.pdf

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Tap on AVAILABLE IN BUNDLE/PACKAGE DEAL to unlock free bonus exams – save more while you get what you need. The COMSAE Phase 1 Form 116 Comprehensive Study Guide – Latest Updated Edition (This Year) is a structured preparation resource designed to help osteopathic medical students strengthen their foundational medical knowledge and confidently prepare for COMSAE Phase 1 assessment success. This in-depth study package provides a clear and practical review of high-yield basic and clinical science concepts commonly tested in COMSAE Phase 1 and COMLEX Level 1–style examinations. The material emphasizes integrated biomedical understanding, disease mechanisms, and clinical reasoning skills required for success in standardized medical assessments. Key content areas include cardiovascular, respiratory, renal, gastrointestinal, endocrine, and neurological physiology; microbiology and infectious disease mechanisms; immunology and inflammatory processes; pharmacology mechanisms of action, indications, and adverse effects; pathology including neoplasia and cellular injury; biochemistry and metabolic pathways; and foundational osteopathic principles and musculoskeletal (OMM/OMT) concepts. The guide also covers biostatistics, epidemiology, and clinical reasoning frameworks used in board-style examinations. The resource includes clinical vignette-based questions, diagnostic reasoning exercises, and multiple-choice board-style review items designed to reflect COMSAE Phase 1 examination expectations. Each item is supported with detailed explanations to strengthen concept integration, improve test-taking strategy, and reinforce high-yield medical knowledge. Special emphasis is placed on applying basic science concepts to clinical scenarios, recognizing disease patterns, understanding pharmacologic mechanisms, and developing structured diagnostic reasoning. The material is designed to help learners transition from memorization to applied clinical thinking.

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Institution
COMSAE PHASE 1
Course
COMSAE PHASE 1

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Page 1 of 165



COMSAE Phase 1 Form 116 EXAM QUESTIONS AND CORRECT
VERIFIED SOLUTIONS LATEST UPDATE THIS YEAR – JUST
RELEASED
COMSAE Phase 1 Form 116 Exam Practice Questions

Below is a comprehensive practice question bank for the COMSAE Phase 1 Form
116 examination with a content distribution that follows the COMLEX-USA Level 1 blueprint .



Exam Overview

COMSAE Phase 1 is designed to help osteopathic medical students gauge their readiness for
COMLEX-USA Level 1. Form 116 is available on a non-secure browser and includes answer keys
with detailed rationales to help identify knowledge gaps .

Content Breakdown (COMLEX-USA Level 1 Blueprint) :


Approximate
Category Topics Included
%



Viscerosomatic reflexes, Chapman points, Fryette's laws,
Osteopathic Principles &
15% sacral/innominate diagnostics, HVLA, muscle energy,
OMM
counterstrain, cranial, lymphatic



Brachial plexus, cranial nerves, spinal cord syndromes, vasc
Human Anatomy 15%
supply, pelvic anatomy, hernias, nerve injuries



Cell injury, inflammation, neoplasia, autoimmune diseases,
Pathology 18%
organ-specific pathology, shock, hemostasis



Cardiac cycle, renal function, acid-base, pulmonary mechan
Physiology 15%
endocrine axes, GI physiology, neurophysiology

, Page 2 of 165



Approximate
Category Topics Included
%



Autonomic drugs, antibiotics, cardiovascular agents, CNS dr
Pharmacology 12%
chemotherapy, endocrine agents, adverse effects



Bacterial/viral/fungal identification, toxins, STIs, CNS infecti
Microbiology/Immunology 10%
HIV, hypersensitivity, immunodeficiencies



Metabolic pathways, vitamin deficiencies, lysosomal storag
Biochemistry/Genetics 8%
diseases, inheritance patterns, inborn errors



Stroke localization, spinal cord syndromes, neurodegenerati
Neurology/Psychiatry 7%
diseases, aphasias, psychiatric disorders


SECTION 1: OSTeopathic Principles & OMM (Questions 1-30)




1. A 45-year-old woman presents with epigastric burning and bloating after meals for several


months. On osteopathic structural exam, you find tenderness and increased tissue texture at


the right T6-T8 paraspinal region. Which viscerosomatic reflex best explains this finding?



A) Gallbladder


B) Pancreas

, Page 3 of 165


C) Liver


D) Stomach



Answer: D) Stomach



Rationale: Viscerosomatic reflexes map spinal cord levels to organs. The stomach corresponds


to T6-T9, with a predilection for the right side. The gallbladder (T7-T9) often presents on the


right, but epigastric symptoms and bilateral T6-T8 tenderness more specifically point to the


stomach .




2. A 28-year-old runner presents with chronic low back pain. On seated flexion test, the right


PSIS moves superiorly earlier and more than the left. In the prone position, the right ILA is more


posterior than the left, and both ILAs move equally with spring test. What is the most likely


sacral diagnosis?



A) Left on left sacral torsion


B) Right on right sacral torsion


C) Left unilateral sacral flexion


D) Bilateral sacral extension

, Page 4 of 165


Answer: B) Right on right sacral torsion



Rationale: The seated flexion test indicates somatic dysfunction on the right. In a sacral torsion,


the side named first is the axis (side of deep sulcus and posterior ILA). Here, the right ILA is


posterior, meaning the axis is on the right. Equal spring test indicates torsion rather than


unilateral flexion.




3. A patient with chronic low back pain has a seated flexion test positive on the left. In the


prone position, the left ILA is more posterior than the right. What is the most likely diagnosis?



A) Left on left sacral torsion


B) Right on right sacral torsion


C) Left unilateral sacral flexion


D) Bilateral sacral extension



Answer: A) Left on left sacral torsion



Rationale: The seated flexion test points to the side of dysfunction (left). A posterior ILA


indicates the axis. In a left on left torsion, the axis is on the left and the left ILA is posterior.

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Institution
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Course
COMSAE PHASE 1

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Uploaded on
June 12, 2026
Number of pages
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Written in
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Type
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