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COMSAE Phase 1 Form 115 ACTUAL EXAM QUESTIONS AND CORRECT VERIFIED SOLUTIONS LATEST UPDATE THIS YEAR – JUST RELEASED.pdf

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Tap on AVAILABLE IN BUNDLE/PACKAGE DEAL to unlock free bonus exams – save more while you get what you need. The COMSAE Phase 1 Form 115 Comprehensive Study Guide – Latest Updated Edition (This Year) is a structured preparation resource designed to help osteopathic medical students strengthen their foundational medical knowledge and confidently prepare for COMSAE Phase 1 assessment success. This in-depth study package provides a clear and practical review of high-yield basic and clinical science concepts commonly tested in COMSAE Phase 1 and COMLEX Level 1–style examinations. The material emphasizes integrated biomedical understanding, disease mechanisms, and clinical reasoning skills required for success in standardized medical assessments. Key content areas include cardiovascular, respiratory, renal, gastrointestinal, endocrine, and neurological physiology; microbiology and infectious disease mechanisms; immunology and inflammatory processes; pharmacology mechanisms of action, indications, and adverse effects; pathology including neoplasia and cellular injury; biochemistry and metabolic pathways; and foundational osteopathic principles and musculoskeletal (OMM/OMT) concepts. The guide also covers biostatistics, epidemiology, and clinical reasoning frameworks used in board-style examinations. The resource includes clinical vignette-based questions, diagnostic reasoning exercises, and multiple-choice board-style review items designed to reflect COMSAE Phase 1 examination expectations. Each item is supported with detailed explanations to strengthen concept integration, improve test-taking strategy, and reinforce high-yield medical knowledge. Special emphasis is placed on applying basic science concepts to clinical scenarios, recognizing disease patterns, understanding pharmacologic mechanisms, and developing structured diagnostic reasoning. The material is designed to help learners transition from memorization to applied clinical thinking.

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COMSAE PHASE 1
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COMSAE PHASE 1

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Page 1 of 156



COMSAE Phase 1 Form 115 EXAM QUESTIONS AND CORRECT
VERIFIED SOLUTIONS LATEST UPDATE THIS YEAR – JUST
RELEASED
COMSAE Phase 1 Form 115 Style Practice Exam with 200 high-yield multiple-choice questions
designed to simulate the content, format, and difficulty of the official NBOME COMSAE Phase 1
Form 115. Each question includes the correct answer and a detailed rationale in italics.

Note: The official COMSAE Phase 1 Form 115 is a copyrighted examination produced by the
National Board of Osteopathic Medical Examiners (NBOME). The questions below are original
practice questions created to help osteopathic medical students prepare for COMSAE and
COMLEX-USA Level 1 by covering the same core content areas .



Brief Exam Coverage: COMSAE Phase 1 Form 115

This exam aligns with the COMLEX-USA Level 1 blueprint and covers the following domains :


Domain Approximate Weight



Osteopathic Principles & Practice (OPP) ~12%



Foundational Biomedical Sciences ~25%



Clinical Systems (Cardio, Pulmonary, Renal, GI, etc.) ~45%



Behavioral Science, Biostatistics, Ethics ~10%



Multisystem/Interdisciplinary Topics ~8%

, Page 2 of 156


COMSAE Phase 1 Form 115 Style Practice Exam (Questions 1–200)



SECTION 1: OSTEOPATHIC PRINCIPLES & PRACTICE (OPP/OMT) – (Qs 1-40)




Q1. A 35-year-old with chronic low back pain has a right posterior innominate rotation. Which


muscle is likely shortened?


A) Left quadratus lumborum


B) Right hamstrings


C) Right iliopsoas


D) Left gluteus maximus



Answer: B


Rationale: A posterior innominate rotation is a shear of the ilium in which the ilium moves


posteriorly on the sacrum. In this dysfunction, the ipsilateral hamstrings are shortened, whereas


the iliopsoas is typically shortened in an anterior innominate. This pattern is essential for


diagnosing sacroiliac dysfunctions and selecting the appropriate muscle-energy treatment .



Q2. During an osteopathic structural exam, you find a T4 spinous process deviated left, with


right rotation restriction. Fryette's Type II mechanics apply. Which of the following is true?

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A) Sidebending and rotation occur to opposite sides


B) Neutral mechanics apply


C) Rotation and sidebending occur to the same side


D) Only rotation is restricted



Answer: C


Rationale: Fryette's Type II (non-neutral) mechanics: rotation and sidebending occur to the same


side. Type I (neutral) mechanics: rotation and sidebending occur to opposite sides. This


distinction is critical for diagnosing and treating spinal dysfunctions using osteopathic


manipulative medicine (OMM) techniques .



Q3. A patient with asthma has tenderness at the 2nd intercostal space, right parasternal region.


This is a Chapman's reflex point for which organ?


A) Kidney


B) Lung


C) Liver


D) Stomach



Answer: B


Rationale: Anterior Chapman's reflex points for the lungs are located in the 2nd intercostal

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space, right and left parasternal. Posterior lung reflex points are found at T2–T4. Chapman's


points are small, tender nodules in the deep fascia that correspond to visceral dysfunction .



Q4. A patient with right lateral bending of the lumbar spine with rotation to the left. According


to Fryette, this is a:


A) Type I dysfunction


B) Type II dysfunction


C) Type III dysfunction


D) Neutral dysfunction



Answer: A


Rationale: In Fryette's Type I (neutral) mechanics, sidebending and rotation occur to opposite


sides. Right lateral bending with left rotation is the classic Type I pattern. This typically occurs in


group curves and involves multiple vertebral segments .



Q5. A 50-year-old with chronic constipation has a tender point at the tip of the 12th rib on the


right. Which viscerosomatic reflex is most likely?


A) Colon


B) Stomach

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