COMAT FBS Comprehensive
Examination Questions With Correct
Answers (Verified Answers) Plus
Rationales 2026 Q&A | Instant
Download Pdf.
1. A 58-year-old man presents with crushing substernal chest pain
radiating to the left arm for 45 minutes. ECG shows ST-segment
elevation in leads II, III, and aVF. Which coronary artery is most
likely occluded?
A. Left anterior descending artery
B. Left circumflex artery
C. Right coronary artery
D. Posterior descending artery
E. Obtuse marginal artery
Answer: C. Right coronary artery
Inferior wall myocardial infarctions involving leads II, III, and aVF are
most commonly caused by occlusion of the right coronary artery.
Patients typically present with chest pain, diaphoresis, nausea, and ECG
changes localized to the inferior leads.
, 2. A 24-year-old woman presents with fatigue and pallor. Laboratory
studies reveal hemoglobin 8.5 g/dL, MCV 68 fL, ferritin decreased,
and TIBC elevated. What is the most likely diagnosis?
A. Thalassemia major
B. Iron deficiency anemia
C. Sideroblastic anemia
D. Anemia of chronic disease
E. Vitamin B12 deficiency
Answer: B. Iron deficiency anemia
Iron deficiency anemia is characterized by microcytic, hypochromic
anemia, low ferritin, elevated TIBC, and reduced serum iron. Common
causes include chronic blood loss, menstruation, and gastrointestinal
bleeding.
3. A 7-year-old child presents with fever, sore throat, and a
sandpaper-like rash. Which organism is the most likely cause?
A. Staphylococcus aureus
B. Corynebacterium diphtheriae
C. Streptococcus pyogenes
D. Haemophilus influenzae
E. Epstein-Barr virus
Answer: C. Streptococcus pyogenes
Scarlet fever is caused by Streptococcus pyogenes producing
erythrogenic toxin. Findings include pharyngitis, fever, strawberry
tongue, and a characteristic sandpaper rash.
, 4. A patient develops sudden dyspnea and pleuritic chest pain after a
prolonged airplane flight. Which diagnostic test is most
appropriate initially in a hemodynamically stable patient?
A. Cardiac catheterization
B. Pulmonary angiography
C. CT pulmonary angiography
D. MRI chest
E. Echocardiography
Answer: C. CT pulmonary angiography
CT pulmonary angiography is the preferred diagnostic test for suspected
pulmonary embolism in stable patients. Risk factors include prolonged
immobility and recent travel.
5. Which cranial nerve is responsible for lateral movement of the
eye?
A. Oculomotor nerve
B. Trochlear nerve
C. Trigeminal nerve
D. Abducens nerve
E. Facial nerve
Answer: D. Abducens nerve
The abducens nerve (CN VI) innervates the lateral rectus muscle, which
abducts the eye. Injury causes medial deviation and horizontal diplopia.
, 6. A 68-year-old smoker presents with hematuria. Which diagnosis
should be considered most strongly?
A. Renal calculi
B. Glomerulonephritis
C. Bladder carcinoma
D. Polycystic kidney disease
E. Pyelonephritis
Answer: C. Bladder carcinoma
Painless hematuria in an older smoker is highly suspicious for bladder
cancer, most commonly urothelial carcinoma. Smoking is the strongest
risk factor.
7. A patient has hypercalcemia, kidney stones, abdominal pain, and
psychiatric symptoms. Which endocrine disorder is most likely?
A. Hypoparathyroidism
B. Primary hyperparathyroidism
C. Addison disease
D. Graves disease
E. SIADH
Answer: B. Primary hyperparathyroidism
The classic presentation of hyperparathyroidism includes “stones, bones,
groans, and psychiatric overtones.” Elevated PTH causes increased
serum calcium and decreased phosphate.
Examination Questions With Correct
Answers (Verified Answers) Plus
Rationales 2026 Q&A | Instant
Download Pdf.
1. A 58-year-old man presents with crushing substernal chest pain
radiating to the left arm for 45 minutes. ECG shows ST-segment
elevation in leads II, III, and aVF. Which coronary artery is most
likely occluded?
A. Left anterior descending artery
B. Left circumflex artery
C. Right coronary artery
D. Posterior descending artery
E. Obtuse marginal artery
Answer: C. Right coronary artery
Inferior wall myocardial infarctions involving leads II, III, and aVF are
most commonly caused by occlusion of the right coronary artery.
Patients typically present with chest pain, diaphoresis, nausea, and ECG
changes localized to the inferior leads.
, 2. A 24-year-old woman presents with fatigue and pallor. Laboratory
studies reveal hemoglobin 8.5 g/dL, MCV 68 fL, ferritin decreased,
and TIBC elevated. What is the most likely diagnosis?
A. Thalassemia major
B. Iron deficiency anemia
C. Sideroblastic anemia
D. Anemia of chronic disease
E. Vitamin B12 deficiency
Answer: B. Iron deficiency anemia
Iron deficiency anemia is characterized by microcytic, hypochromic
anemia, low ferritin, elevated TIBC, and reduced serum iron. Common
causes include chronic blood loss, menstruation, and gastrointestinal
bleeding.
3. A 7-year-old child presents with fever, sore throat, and a
sandpaper-like rash. Which organism is the most likely cause?
A. Staphylococcus aureus
B. Corynebacterium diphtheriae
C. Streptococcus pyogenes
D. Haemophilus influenzae
E. Epstein-Barr virus
Answer: C. Streptococcus pyogenes
Scarlet fever is caused by Streptococcus pyogenes producing
erythrogenic toxin. Findings include pharyngitis, fever, strawberry
tongue, and a characteristic sandpaper rash.
, 4. A patient develops sudden dyspnea and pleuritic chest pain after a
prolonged airplane flight. Which diagnostic test is most
appropriate initially in a hemodynamically stable patient?
A. Cardiac catheterization
B. Pulmonary angiography
C. CT pulmonary angiography
D. MRI chest
E. Echocardiography
Answer: C. CT pulmonary angiography
CT pulmonary angiography is the preferred diagnostic test for suspected
pulmonary embolism in stable patients. Risk factors include prolonged
immobility and recent travel.
5. Which cranial nerve is responsible for lateral movement of the
eye?
A. Oculomotor nerve
B. Trochlear nerve
C. Trigeminal nerve
D. Abducens nerve
E. Facial nerve
Answer: D. Abducens nerve
The abducens nerve (CN VI) innervates the lateral rectus muscle, which
abducts the eye. Injury causes medial deviation and horizontal diplopia.
, 6. A 68-year-old smoker presents with hematuria. Which diagnosis
should be considered most strongly?
A. Renal calculi
B. Glomerulonephritis
C. Bladder carcinoma
D. Polycystic kidney disease
E. Pyelonephritis
Answer: C. Bladder carcinoma
Painless hematuria in an older smoker is highly suspicious for bladder
cancer, most commonly urothelial carcinoma. Smoking is the strongest
risk factor.
7. A patient has hypercalcemia, kidney stones, abdominal pain, and
psychiatric symptoms. Which endocrine disorder is most likely?
A. Hypoparathyroidism
B. Primary hyperparathyroidism
C. Addison disease
D. Graves disease
E. SIADH
Answer: B. Primary hyperparathyroidism
The classic presentation of hyperparathyroidism includes “stones, bones,
groans, and psychiatric overtones.” Elevated PTH causes increased
serum calcium and decreased phosphate.
