NAADAC 2026 EOC EXAM SET QUESTIONS AND
ANSWERS SURE A+
✔✔What is the necessary first step toward recovery from an SUD? - ✔✔Detoxification
✔✔What are two substances that may necessitate medical supervision during detox to
address potential seizure risk? - ✔✔Alcohol and benzodiazepines
✔✔What kinds of substances have the highest abuse liability? - ✔✔Those that produce
euphoria and have a rapid onset of action
✔✔Which Schedule of drug has no currently accepted medical use and a high potential
for abuse? These are the most dangerous drugs with potentially severe psychological or
physical dependence. Examples include: heroin, LSD, cannabis, ecstasy,
methaqualone, and peyote. - ✔✔Schedule I
✔✔Which Schedule of drug has a high potential for abuse, with use potentially leading
to severe psychological or physical dependence, but are sometimes used medically?
Examples include Vicodin, cocaine, methamphetamine, methadone, Dilaudid,
OxyContin, Demerole, Fentanyl, Dexedrine, Adderall, and Ritalin. - ✔✔Schedule II
✔✔Which Schedule of drug has a moderate to low potential for dependence and lower
abuse potential? Examples include Tylenol, codeine, Ketamine, steroids, testosterone. -
✔✔Schedule III
✔✔Which Schedule of drug has a low potential for abuse and low risk of dependence?
Examples: Xanax, Ativan, Soma, Talwin, Darvon, Ambien, Darvocet, Valium, Tramadol
- ✔✔Schedule IV
✔✔Which Schedule of drug has the lowest potential for abuse and is typically used for
antidiarrheal, antitussive, and analgesis purposes? Examples: Robitussin, Lomotil,
Motofen, Lyrica, Parepectolin - ✔✔Schedule V
✔✔What is a designer drug? - ✔✔A substance or chemical that is structurally an
imitation of a controlled substance
✔✔According to NAADAC, what are the most intense, rapid and efficient methods of
drug use? - ✔✔Intravenous and smoking
✔✔How long does it usually take for blood to complete one circulation throughout the
body, if it is successful at penetrating the blood-brain barrier? - ✔✔One minute
, ✔✔What kinds of chemicals are able to pass through the blood-brain barrier without a
problem? - ✔✔Very small and/or fat soluble
✔✔The ____ of a substance is the amount of time required for the concentration or
amount of a psychoactive substance in the body to be reduced by one-half - ✔✔Half-life
✔✔What is the fastest substance administration method? What is the most direct route
to the brain? Least efficient? - ✔✔Smoking/inhalation; injection; ingestion
✔✔The part of the central nervous system responsible for a person's state of arousal
and partly responsible for monitoring when an individual is awake and asleep. - ✔✔The
reticular activating system (RAS)
✔✔The ____ regulates a person's emotions, motivation, and memory formation. -
✔✔Limbic system
✔✔The ____ is the part of the CNS responsible for involuntary and fine motor skills. -
✔✔Basal ganglia
✔✔The ____ is the part of the CNS responsible for movement coordination and
processing sensory input. - ✔✔Cerebellum
✔✔The ____ processes sensory data and the ____ is the executive center of the brain,
where a person thinks, plans, solves problems, and makes decisions. - ✔✔Cerebral
cortex; prefrontal cortex
✔✔What is the Pleasure Reward Pathway (PRP), which controls a person's motivations
and responses to natural and artificial rewards, comprised of? - ✔✔Ventral tegmental
area; nucleus accumbens; prefrontal cortex
✔✔What is the primary neurotransmitter associated with the Pleasure Reward
Pathway? - ✔✔Dopamine
✔✔What does the release of dopamine do? - ✔✔Emotionally heightens the rewarding
aspects of a behavior by giving a person a jolt of pleasure
✔✔Which region of the limbic system acts as a liaison between the central and
autonomic nervous system and works to achieve and maintain homeostasis? -
✔✔Hypothalamus
✔✔This neurotransmitter is both inhibitory and excitatory and is influenced by
hallucinogens, caffeine, and nicotine - ✔✔Acetylcholine
ANSWERS SURE A+
✔✔What is the necessary first step toward recovery from an SUD? - ✔✔Detoxification
✔✔What are two substances that may necessitate medical supervision during detox to
address potential seizure risk? - ✔✔Alcohol and benzodiazepines
✔✔What kinds of substances have the highest abuse liability? - ✔✔Those that produce
euphoria and have a rapid onset of action
✔✔Which Schedule of drug has no currently accepted medical use and a high potential
for abuse? These are the most dangerous drugs with potentially severe psychological or
physical dependence. Examples include: heroin, LSD, cannabis, ecstasy,
methaqualone, and peyote. - ✔✔Schedule I
✔✔Which Schedule of drug has a high potential for abuse, with use potentially leading
to severe psychological or physical dependence, but are sometimes used medically?
Examples include Vicodin, cocaine, methamphetamine, methadone, Dilaudid,
OxyContin, Demerole, Fentanyl, Dexedrine, Adderall, and Ritalin. - ✔✔Schedule II
✔✔Which Schedule of drug has a moderate to low potential for dependence and lower
abuse potential? Examples include Tylenol, codeine, Ketamine, steroids, testosterone. -
✔✔Schedule III
✔✔Which Schedule of drug has a low potential for abuse and low risk of dependence?
Examples: Xanax, Ativan, Soma, Talwin, Darvon, Ambien, Darvocet, Valium, Tramadol
- ✔✔Schedule IV
✔✔Which Schedule of drug has the lowest potential for abuse and is typically used for
antidiarrheal, antitussive, and analgesis purposes? Examples: Robitussin, Lomotil,
Motofen, Lyrica, Parepectolin - ✔✔Schedule V
✔✔What is a designer drug? - ✔✔A substance or chemical that is structurally an
imitation of a controlled substance
✔✔According to NAADAC, what are the most intense, rapid and efficient methods of
drug use? - ✔✔Intravenous and smoking
✔✔How long does it usually take for blood to complete one circulation throughout the
body, if it is successful at penetrating the blood-brain barrier? - ✔✔One minute
, ✔✔What kinds of chemicals are able to pass through the blood-brain barrier without a
problem? - ✔✔Very small and/or fat soluble
✔✔The ____ of a substance is the amount of time required for the concentration or
amount of a psychoactive substance in the body to be reduced by one-half - ✔✔Half-life
✔✔What is the fastest substance administration method? What is the most direct route
to the brain? Least efficient? - ✔✔Smoking/inhalation; injection; ingestion
✔✔The part of the central nervous system responsible for a person's state of arousal
and partly responsible for monitoring when an individual is awake and asleep. - ✔✔The
reticular activating system (RAS)
✔✔The ____ regulates a person's emotions, motivation, and memory formation. -
✔✔Limbic system
✔✔The ____ is the part of the CNS responsible for involuntary and fine motor skills. -
✔✔Basal ganglia
✔✔The ____ is the part of the CNS responsible for movement coordination and
processing sensory input. - ✔✔Cerebellum
✔✔The ____ processes sensory data and the ____ is the executive center of the brain,
where a person thinks, plans, solves problems, and makes decisions. - ✔✔Cerebral
cortex; prefrontal cortex
✔✔What is the Pleasure Reward Pathway (PRP), which controls a person's motivations
and responses to natural and artificial rewards, comprised of? - ✔✔Ventral tegmental
area; nucleus accumbens; prefrontal cortex
✔✔What is the primary neurotransmitter associated with the Pleasure Reward
Pathway? - ✔✔Dopamine
✔✔What does the release of dopamine do? - ✔✔Emotionally heightens the rewarding
aspects of a behavior by giving a person a jolt of pleasure
✔✔Which region of the limbic system acts as a liaison between the central and
autonomic nervous system and works to achieve and maintain homeostasis? -
✔✔Hypothalamus
✔✔This neurotransmitter is both inhibitory and excitatory and is influenced by
hallucinogens, caffeine, and nicotine - ✔✔Acetylcholine
