PREMIUM ANSWER COLLECTION
◉ Sumatriptan MOA.
Answer: Selective 5-HT1 receptor agonist, constricts cranial blood
vessels and inhibits the release of vasoactive peptides, thereby
reducing migraine symptoms.
◉ Sumatriptan Contraindications.
Answer: History of ischemic heart disease, coronary artery spasm,
stroke, uncontrolled hypertension. Peripheral vascular disease.
◉ Acetylcysteine Drug Class.
Answer: Antidote, Mucolytic
◉ Acetylcysteine MOA.
Answer: Acts as a precursor to glutathione, which neutralizes the
toxic metabolites of acetaminophen and helps to detoxify the liver.
◉ Acetylcysteine Dosage for acetaminophen overdose.
Answer: 140 mg/kg IV loading dose, followed by 70 mg/kg every 4
hours for 17 doses.
,◉ Methylphenidate Drug Class.
Answer: CNS Stimulant
◉ Methylphenidate MOA.
Answer: Increases dopamine and norepinephrine in the brain by
inhibiting their reuptake, resulting in increased attention and focus.
◉ Methylphenidate Contraindications.
Answer: Glaucoma, severe anxiety, Tourette syndrome, recent
myocardial infarction.
◉ Valproic acid Drug Class.
Answer: Anticonvulsant, Mood Stabilizer
◉ Valproic acid MOA.
Answer: Increases GABA levels in the brain, stabilizing neuronal
activity and reducing seizure activity.
◉ Valproic acid Contraindications.
Answer: Liver disease, pregnancy (teratogenic). Urea cycle
disorders.
, ◉ Phenobarbital Drug Class.
Answer: Barbiturate
◉ Phenobarbital MOA.
Answer: Enhances GABA activity, producing CNS depression,
anticonvulsant, and sedative effects.
◉ Phenobarbital Contraindications.
Answer: Severe respiratory depression, acute intermittent
porphyria.
◉ Phenytoin Drug Class.
Answer: Hydantoin Anticonvulsant
◉ Phenytoin MOA.
Answer: Stabilizes neuronal membranes by inhibiting sodium
channels, preventing seizures.
◉ Phenytoin Therapeutic Drug Level.
Answer: 10-20 mcg/mL
◉ Lorazepam Drug Class.