2026 QUESTIONS WITH ANSWERS GRADED
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• Pharmacokinetics.
Answer: The process in which medications move through the body
• What are the 4 phases of pharmacokinetics?.
Answer: absorption, distribution, metabolism, excretion
• Absorption.
Answer: happens with drug movement from the GI tract into the
bloodstream. Most meds are taken by mouth.
• Loop Diuretic Review Nursing.
Answer: Furosemide is classified as what?
• Oral absorption Usually takes 2-4 hours •Enteric coated aspirin - hard on
stomach can not crush pill •Extended release absorbed in the small intestine.
Answer: Takes awhile to get absorbed because it has to go through the GI
system
• Potassium Sparing Diuretic.
Answer: Spironolactone is classified as what?
• IM absorption.
Answer: Absorbed 1-2 hours
• Thiazide Diuretic.
Answer: hydrochlorothiazide is classified as what?
• Osmotic.
Answer: Mannitol is classified as what?
• Alpha Adrenergic Blocker.
Answer: prazosin is classified as what?
,• IV absorption.
Answer: Absorbed 30-60 minutes
• Calcium Channel Blocker.
Answer: Nifedipine is classified as what?
• dissolution Liquid medications are absorbed faster than solids. Food can
interfere with the absorption of drugs..
Answer: Dissolution happens when a po medication breaks down into
particles, disintegrates, and dissolves to combine with liquid so absorption
from the GI tract into the bloodstream occurs.
• Cardiac Selective Beta Blocker.
Answer: metoprolol is classified as what?
• Nonselective Beta Blocker.
Answer: Propranolol is classified as what?
• Angiotensin Converting Enzyme (ACE) Inhibitor.
Answer: lisinopril is classified as what?
• Angiotensin II Receptor Blockers.
Answer: valsartan is classified as what?
• Antitubercular.
Answer: Isoniazid is classified as what?
• Drugs that resist dissolution Enteric coated medications are designed to
resist disintegration until the pill reaches the small intestine. EC and
sustained release meds should not be crushed..
Answer: Parenteral medications (SL, eyedrops, inhalants, transdermal) do
not pass through the GI tract.
• Antitubercular.
Answer: Rifampin is classified as what?
• Factors that affect absorption •Food consumption - will change medicine
potency (delayed) •Stress - Exercise, medicine goes to muscle •pH -
, Medicine is made for acidic environments •Antacid changes absorption
•Taken alone so it doesn't change the action.
Answer: •Lack of muscle and increased fat changes medicine absorption
• Excipients Sometimes an excipient enhances the absorption of a drug such
as with PCN, which is not well absorbed from the GI tract. Adding Na to
PCN, which makes it penicillin sodium, will increase the absorption of
PCN.
Answer: Fillers and other substances that make up tablets as a pill is not
100% drug.
• first pass effect •Only happens with oral medications.
Answer: •the oral drugs go to liver via portal vein where some of the drug
becomes inactive
• delayed gastric emptying.
Answer: Food doesn't move like it should
• Adrenergic Agonists.
Answer: Pseudoephedrine is classified as what?
• Distribution.
Answer: refers to the movement of the drug from the circulation to body
tissues
• Decongestants.
Answer: Oxymetazoline HCL is classified as what?
• Factors affecting distribution -protein binding -blood brain barrier -drug's
affinity to the tissue.
Answer: -blood flow to tissues
• protein binding Some drugs are highly protein bound and other are weakly
protein bound.
Answer: Drugs bind with proteins in blood
• Antihistamines.
Answer: Diphenhydramine (Benadryl) is classified as what?
, • free drugs.
Answer: drugs not bound to protein
• Antihistamines.
Answer: Loratadine is classified as what?
• Antitussive.
Answer: Destromethorphan Hydrobromide is classified as what?
• Drug Toxicity -it is important to know if you are administering highly
protein bound medications and monitor albumin levels in patients with liver
or kidney disease. -Some drugs that are highly protein bound include:
Warfarin Furosemide Diazepam.
Answer: -Two highly protein bound drugs compete and one might
accumulate and cause a toxicity
• Drug distribution and albumin -This can be fatal with some meds. -Free
drugs are those not bound to protein, which means they are active in the
body and cause a pharmacologic response. -Older adults, malnourished
individuals, and those with liver or kidney disease have low albumin levels..
Answer: -A decrease in albumin levels decrease the protein-binding sites,
which means more of the free drug is circulated.
• Expectorant.
Answer: Guaifenesin is classified as what?
• Blood Brain Barrier (BBB) -Some meds are able to cross the BBB such as
benzodiazepines. -Drugs can cross the placenta and cause spontaneous
abortion or alter fetal growth and development..
Answer: -The BBB protects the brain from most drugs.
• Glucocorticoids Intranasal.
Answer: Fluticasone is classified as what?
• Metabolism •Liver primary site.
Answer: •Chemically changes drug to a form that can be excreted
• Beta 2 Adrenergic Agonist.