QUESTIONS AND CORRECTLY WELL
DEFINED ANSWERS LATEST ALREADY
GRADED A+
T/F: The FDA issued GLPs with the dual goal of establishing
standards for the conduct of safety studies in support of
new applications and defining a policy for enforcement. -
ANSWERS-True
Which of the following information need not be present on
an official tag?
-Date of birth
-Numbers identifying the dealer
-Numbers identifying the animal
-The letters "USDA" - ANSWERS-Date of birth
T/F: In the course of a GLP study, all data forms must be
incorporated in either a protocol or an SOP. - ANSWERS-
False
,What best describes acceptable euthanasia methods?
-They cause immediate cessation of life.
-They have no effects on the personnel doing the procedure.
-They consistently produce a humane death.
-They are the most convenient method when large numbers
of animals must be euthanized. - ANSWERS-They
consistently produce a humane death.
T/F: A reflex movement during the euthanasia procedure
indicates that the unconscious animal is still experiencing
pain. - ANSWERS-False
T/F: The testing facility management is responsible to
ensure that corrective actions are taken when problems
have been identified by the QAU. - ANSWERS-True
T/F: Animal welfare is one of the most important topics
addressed in the GLPs. - ANSWERS-False
T/F: When a new version of an SOP is produced, all copies of
the older version must be removed from laboratory areas. -
ANSWERS-True
,Which of the following statements is not true about
reagents and solutions used in studies that follow GLPs?
-They must be stored under conditions appropriate for the
particular substance being used.
-They must be destroyed at the end of a study by the study
director or other trained personnel.
-They must be stored in a container that shows name, CAS
number, batch number, and expiration date.
-They must be periodically tested to ensure uniformity. -
ANSWERS-They must be destroyed at the end of a study by
the study director or other trained personnel.
Which of the following statements regarding decapitation is
FALSE?
-Decapitation can be used on a variety of small animals.
-The AVMA Guidelines list decapitation as an "acceptable"
method.
-It should be used on unanesthetized animals when it is
required by the experimental design and approved by the
IACUC.
-The equipment used to perform decapitation poses a
hazard to the operator. - ANSWERS-The AVMA Guidelines
list decapitation as an "acceptable" method.
, Which organization at the NIH is charged with ensuring
compliance with the PHS Policy?
-Animal and Plant Health Inspection Service (APHIS)
-Office of Laboratory Animal Welfare (OLAW)
-Food and Drug Administration (FDA)
-United States Department of Agriculture (USDA) -
ANSWERS-Office of Laboratory Animal Welfare (OLAW)
Which of the following statements is TRUE when using
carbon dioxide for euthanasia?
-Pulmonary lesions may occur if the carbon dioxide
concentration reaches 40%.
-It is best to combine carbon dioxide with oxygen for
euthanasia.
-The optimal flow rate is one that displaces 10% - 30% of the
chamber volume every minute.
-Gas flow should be maintained for at least 1 minute after
apparent death to ensure the animal does not recover. -
ANSWERS-Gas flow should be maintained for at least 1
minute after apparent death to ensure the animal does not
recover.