WGU D027 STUDY GUIDE DOCUMENT 2026/2027 | ADVANCED
PRACTICE NURSING | 60 VERIFIED QUESTIONS
Autosomal Dominant - CORRECT ANSWERS-1 parent has, 50% change of child
having
Autosomal Recessive - CORRECT ANSWERS-Both parents are carriers, 25% change
of child having, 50% chance child is a carrier.
Cystic Fibrosis - CORRECT ANSWERS-affects pancreas causing secretions in lungs
21st Trisomy - CORRECT ANSWERS-Down Syndrome
Klinefelter Syndrome (XXY) - CORRECT ANSWERS-male has extra X, female like
qualities
Turner Syndrome - CORRECT ANSWERS-Missing X in females
Alpha Thalassemia - CORRECT ANSWERS-inherited blood disorder; mild to severe
anemia
Beta Thallasemia - CORRECT ANSWERS-low hemoglobin; contraindicated
medication ferrous sulfate
Prevalence Risk - CORRECT ANSWERS-proportion of the population affected at a
certain time
,Incidence rate - CORRECT ANSWERS-number of new cases divided by population
Innate immunity - CORRECT ANSWERS-inflammation; increased vascular
permeability
B&T lymphocytes - CORRECT ANSWERS-immune response
primary malignant tumor - CORRECT ANSWERS-lack of organization of cells
glucocorticoids - CORRECT ANSWERS-used in combination with other agent to treat
lymphoid tissue (leukemia). glucocorticoids are directly toxic to lymphoid
tissues.
Selective estrogen receptor modulators (SERM) - CORRECT ANSWERS-for hormone
receptor positive and advanced breast cancer. (Tamoxifin reduces risk and
recurrence risk)
Heart failure - CORRECT ANSWERS-impairment of the ventricle to fill with or eject
blood; heart cannot meet metabolic need of the body.
CHF - CORRECT ANSWERS-heart cannot keep up with metabolic needs; volume
overload in pulmonary area
Left Ventricular Dysfunction - CORRECT ANSWERS-reduced ejection fraction;
ventricle having issue ejecting blood.
, normal ejection fraction - CORRECT ANSWERS-55 - 60 % (blood pumped out with
each heartbeat)
Ejection fraction of 50% - reduced or preserved? - CORRECT ANSWERS-preserved
Diastolic CHF - CORRECT ANSWERS-preserved ejection fraction, problem is with
filling
Systolic CHF - CORRECT ANSWERS-reduced ejection fraction, problem is with
ejecting
Left sided CHF - CORRECT ANSWERS-pulmonary (JVD, fluid volume overload, rails,
S-3 murmurs) ** #1 cause of Right sided CHF
BNP - CORRECT ANSWERS-gold standard lab test to diagnose CHF
Echocardiogram - CORRECT ANSWERS-Diagnostic tool, evaluates heart structure
and function
At Risk for HF - Stage A - CORRECT ANSWERS-no structural heart disease or
symptoms of heart failure
Stage A HF co-morbidities - CORRECT ANSWERS-htn, atherosclerotic disease,
diabetes, metabolic syndrome, patients using cardiotoxins with family history
PRACTICE NURSING | 60 VERIFIED QUESTIONS
Autosomal Dominant - CORRECT ANSWERS-1 parent has, 50% change of child
having
Autosomal Recessive - CORRECT ANSWERS-Both parents are carriers, 25% change
of child having, 50% chance child is a carrier.
Cystic Fibrosis - CORRECT ANSWERS-affects pancreas causing secretions in lungs
21st Trisomy - CORRECT ANSWERS-Down Syndrome
Klinefelter Syndrome (XXY) - CORRECT ANSWERS-male has extra X, female like
qualities
Turner Syndrome - CORRECT ANSWERS-Missing X in females
Alpha Thalassemia - CORRECT ANSWERS-inherited blood disorder; mild to severe
anemia
Beta Thallasemia - CORRECT ANSWERS-low hemoglobin; contraindicated
medication ferrous sulfate
Prevalence Risk - CORRECT ANSWERS-proportion of the population affected at a
certain time
,Incidence rate - CORRECT ANSWERS-number of new cases divided by population
Innate immunity - CORRECT ANSWERS-inflammation; increased vascular
permeability
B&T lymphocytes - CORRECT ANSWERS-immune response
primary malignant tumor - CORRECT ANSWERS-lack of organization of cells
glucocorticoids - CORRECT ANSWERS-used in combination with other agent to treat
lymphoid tissue (leukemia). glucocorticoids are directly toxic to lymphoid
tissues.
Selective estrogen receptor modulators (SERM) - CORRECT ANSWERS-for hormone
receptor positive and advanced breast cancer. (Tamoxifin reduces risk and
recurrence risk)
Heart failure - CORRECT ANSWERS-impairment of the ventricle to fill with or eject
blood; heart cannot meet metabolic need of the body.
CHF - CORRECT ANSWERS-heart cannot keep up with metabolic needs; volume
overload in pulmonary area
Left Ventricular Dysfunction - CORRECT ANSWERS-reduced ejection fraction;
ventricle having issue ejecting blood.
, normal ejection fraction - CORRECT ANSWERS-55 - 60 % (blood pumped out with
each heartbeat)
Ejection fraction of 50% - reduced or preserved? - CORRECT ANSWERS-preserved
Diastolic CHF - CORRECT ANSWERS-preserved ejection fraction, problem is with
filling
Systolic CHF - CORRECT ANSWERS-reduced ejection fraction, problem is with
ejecting
Left sided CHF - CORRECT ANSWERS-pulmonary (JVD, fluid volume overload, rails,
S-3 murmurs) ** #1 cause of Right sided CHF
BNP - CORRECT ANSWERS-gold standard lab test to diagnose CHF
Echocardiogram - CORRECT ANSWERS-Diagnostic tool, evaluates heart structure
and function
At Risk for HF - Stage A - CORRECT ANSWERS-no structural heart disease or
symptoms of heart failure
Stage A HF co-morbidities - CORRECT ANSWERS-htn, atherosclerotic disease,
diabetes, metabolic syndrome, patients using cardiotoxins with family history
