BENJAMIN CAVILL I HUMAN CASE EXAM STUDY SHEET 2026 UPDATED QUESTIONS AND SOLUTIONS

BENJAMIN CAVILL I HUMAN CASE EXAM
STUDY SHEET 2026 UPDATED QUESTIONS
AND SOLUTIONS



◉ case study 4 what does the mutation do.
Answer: Causes constant tyrosine kinase activity


◉ case study 4 what is the typical CBC finding.
Answer: Marked leukocytosis with left shift


◉ case study 4 what is seen on differential.
Answer: Many myelocytes with basophilia and eosinophilia


◉ case study 4 what happens to platelets.
Answer: They are often increased (thrombocytosis)


◉ case study 4 what is the bone marrow ratio.
Answer: Very high myeloid to erythroid ratio (~40:1)

, ◉ case study 4 how many blasts are present.
Answer: Less than 5% in chronic phase


◉ case study 4 what physical finding is common.
Answer: Splenomegaly


◉ case study 4 what is the classic pattern for CML.
Answer: Leukocytosis with basophilia and left shift


◉ case study 7 what conditions should be included in the differential
diagnosis.
Answer: Nutritional deficiencies (B12/folate) and myelodysplastic
syndrome (MDS)


◉ case study 7 what other conditions could be considered.
Answer: Acute leukemia and bone marrow infiltration (e.g., hairy
cell leukemia)


◉ case study 7 why these conditions are considered.
Answer: Because the patient presents with pancytopenia affecting
all cell lines


◉ case study 7 what additional test helps confirm the diagnosis.