REPLICATION AND REPAIR PRACTICE SET
ANSWERS FULL SOLUTION
◉ What is the structure of DNA described as?
Answer: A double helix, similar to a twisted ladder.
◉ What are Chargaff's rules regarding nucleotide composition?
Answer: A=T and G=C; the amounts of A, T, G, and C vary among
species.
◉ Who studied the structure of DNA using X-ray diffraction?
Answer: Rosalind Franklin
◉ What did Watson and Crick contribute to the understanding of
DNA?
Answer: They proposed the double helix model of DNA structure.
◉ What is semiconservative replication?
Answer: Each strand of the original DNA serves as a template for a
new strand.
, ◉ What is the role of DNA helicase in DNA replication?
Answer: It unwinds and separates the two strands of the DNA
molecule.
◉ What are the two types of strands formed during DNA replication?
Answer: Leading strand and lagging strand.
◉ What enzyme is responsible for joining nucleotides in the lagging
strand?
Answer: DNA ligase
◉ How does prokaryotic DNA replication differ from eukaryotic
replication?
Answer: Prokaryotic replication occurs in a single circular loop,
while eukaryotic replication occurs at multiple origins along linear
chromosomes.
◉ What is the function of telomerase?
Answer: It replicates the ends of chromosomes (telomeres).
◉ What is the average error rate of DNA polymerase during
replication?
Answer: About one mistake per 100,000 base pairs.