MOLECULAR BIOLOGY ASSESSMENT
QUESTIONS SOLUTIONS GRADED A+
◉ What is a key requirement for genetic material?
Answer: Must be able to store genetic information.
◉ What did Griffith's experiment demonstrate?
Answer: That DNA can transform non-virulent bacteria into virulent
bacteria.
◉ What was the outcome of Griffith's transformation experiment
with mice?
Answer: Mice injected with the S strain died; those with the R strain
lived.
◉ What did Avery's experiments show about DNA?
Answer: DNA is the transforming substance that allows bacteria to
become virulent.
◉ What did the Hershey and Chase experiment conclude?
, Answer: Only DNA, not protein, is the genetic material that
transforms bacteria.
◉ What is the structure of DNA described as?
Answer: A double helix, similar to a twisted ladder.
◉ What are Chargaff's rules regarding nucleotide composition?
Answer: A=T and G=C; the amounts of A, T, G, and C vary among
species.
◉ Who studied the structure of DNA using X-ray diffraction?
Answer: Rosalind Franklin
◉ What did Watson and Crick contribute to the understanding of
DNA?
Answer: They proposed the double helix model of DNA structure.
◉ What is semiconservative replication?
Answer: Each strand of the original DNA serves as a template for a
new strand.
◉ What is the role of DNA helicase in DNA replication?