NSG 552 Psychopharmacology Wilkes Exam 3 Study Guide
Questions and Guide Answers
100% Verified Graded A+
1. First Line Treatments for alcohol use disorder (according to Study Guide &
Dynamed)
Answer: naltrexone and acamprosate
2. Second Line Treatments for alcohol use disorder (according to study guide but
not dynamed)
Answer: Disulfuram and Bupropion (not FDA approved for ETOH but second line according to study guide)
3. Second Line Treatment for alcohol use disorder (according to Dynamed)
Answer: -
Disulfuram
4. Other off label medications for alcohol use disorder according to Dynamed-
Answer: Topiramate, gabapentin, baclofen
, 5. Other off label medications for alcohol use disorder according to Stahl's
Answer: Top- iramate, ondansetron
6. MOA of Naltrexone
Answer: Opioid Receptor Antagonist
7. MOA of Acamprosate
Answer: - weak GABAa agonist
- weak NMDA antagonist
(does not prevent withdrawal symptoms)
8. MOA of Disulfuram
Answer: inhibits enzyme (aldehyde dehydrogenase) in the liver
9. Bupropions role in alcohol use disorder
Answer: Can diminish cravings for etoh, treat underlying anxiety/depression
10. Safety Risk associated with bupropion and etoh
Answer: bupropion increases the risk of seizures in those going through etoh withdrawal
11. s/s ETOH intoxication
Answer: impaired fine motor control, impaired judgement and coordination, ataxic gait, poor balance,
lethargy, diflculty sitting upright, diflculty with memory and sitting upright, N/V, coma in levels 300mg/dL and over
Questions and Guide Answers
100% Verified Graded A+
1. First Line Treatments for alcohol use disorder (according to Study Guide &
Dynamed)
Answer: naltrexone and acamprosate
2. Second Line Treatments for alcohol use disorder (according to study guide but
not dynamed)
Answer: Disulfuram and Bupropion (not FDA approved for ETOH but second line according to study guide)
3. Second Line Treatment for alcohol use disorder (according to Dynamed)
Answer: -
Disulfuram
4. Other off label medications for alcohol use disorder according to Dynamed-
Answer: Topiramate, gabapentin, baclofen
, 5. Other off label medications for alcohol use disorder according to Stahl's
Answer: Top- iramate, ondansetron
6. MOA of Naltrexone
Answer: Opioid Receptor Antagonist
7. MOA of Acamprosate
Answer: - weak GABAa agonist
- weak NMDA antagonist
(does not prevent withdrawal symptoms)
8. MOA of Disulfuram
Answer: inhibits enzyme (aldehyde dehydrogenase) in the liver
9. Bupropions role in alcohol use disorder
Answer: Can diminish cravings for etoh, treat underlying anxiety/depression
10. Safety Risk associated with bupropion and etoh
Answer: bupropion increases the risk of seizures in those going through etoh withdrawal
11. s/s ETOH intoxication
Answer: impaired fine motor control, impaired judgement and coordination, ataxic gait, poor balance,
lethargy, diflculty sitting upright, diflculty with memory and sitting upright, N/V, coma in levels 300mg/dL and over
