BIO 340 FINAL EXAM CELL STRUCTURE
SIGNALING PATHWAYS AND
REGULATION PRACTICE QUESTIONS AND
ANSWERS
●● More than one protein can be encoded from one gene by use of
Answer: RNA editing and Alternative splicing (Both A & C)
●● How can an inhibitor/repressor protein carry out post-transcriptional
control of gene expression?
Answer: An inhibitor/repressor can bind mRNA and inhibit alternative
splicing.
●● Which of the following is a common motif found in transcriptional
regulators?
Answer: Helix loop helix motif
Zinc finger motif
Leucine Zipper motif
All of the Above^
●● Which is an expected characteristic of master transcription
regulators?
Answer: They bind to cis regulatory sequences of multiple genes.
,●● Which of the following is NOT true for transcriptional regulation of
eukaryotic genes.
Answer: Multiple cis-regulatory regions of a gene either all equally
activate transcription, or all equally repress transcription.
●● A hypothetical Zinc-finger protein, we will call it protein-X, is active
only in neurons. It is only active when phosphorylated. Which of the
following statements is consistent with these facts?
Answer: All of the Above
The cis-regulatory sequences to which this protein-X binds, are
regulating a gene that is transcribed only in neurons. The "activity" of
this protein X is its ability to bind specific DNA sequences.This protein-
X is the substrate of a kinase that is only active in neurons.
●● TATA box binding (TBP) protein binds directly to
Answer: Promoter region
●● A dimerized helix-loop-helix transcription regulator binds directly to
Answer: Cis-regulatory sequences
●● Repressors or activators of alternative splicing bind directly to
Answer: Intron consensus sequences
, ●● miRNA (microRNA)
Answer: carry out RNA interference as a means of post-transcriptional
control.
●● mRNA
Answer: RNA that codes for protein
●● U2 or U4 snRNA
Answer: Spliceosome Ribozymes involved in mRNA processing
●● Genes that are active in all cell types are expected to be found in
constitutive heterochromatin regions of chromosomes.
Answer: False
●● Leucine zipper transcription regulators bind DNA with their repeated
leucine stretch.
Answer: False
●● Pentoses (5-carbon sugars) are significant in cells because
Answer: They are the sugar component of deoxyribonucleotides and
ribonucleotides.
●● Condensation reactions
SIGNALING PATHWAYS AND
REGULATION PRACTICE QUESTIONS AND
ANSWERS
●● More than one protein can be encoded from one gene by use of
Answer: RNA editing and Alternative splicing (Both A & C)
●● How can an inhibitor/repressor protein carry out post-transcriptional
control of gene expression?
Answer: An inhibitor/repressor can bind mRNA and inhibit alternative
splicing.
●● Which of the following is a common motif found in transcriptional
regulators?
Answer: Helix loop helix motif
Zinc finger motif
Leucine Zipper motif
All of the Above^
●● Which is an expected characteristic of master transcription
regulators?
Answer: They bind to cis regulatory sequences of multiple genes.
,●● Which of the following is NOT true for transcriptional regulation of
eukaryotic genes.
Answer: Multiple cis-regulatory regions of a gene either all equally
activate transcription, or all equally repress transcription.
●● A hypothetical Zinc-finger protein, we will call it protein-X, is active
only in neurons. It is only active when phosphorylated. Which of the
following statements is consistent with these facts?
Answer: All of the Above
The cis-regulatory sequences to which this protein-X binds, are
regulating a gene that is transcribed only in neurons. The "activity" of
this protein X is its ability to bind specific DNA sequences.This protein-
X is the substrate of a kinase that is only active in neurons.
●● TATA box binding (TBP) protein binds directly to
Answer: Promoter region
●● A dimerized helix-loop-helix transcription regulator binds directly to
Answer: Cis-regulatory sequences
●● Repressors or activators of alternative splicing bind directly to
Answer: Intron consensus sequences
, ●● miRNA (microRNA)
Answer: carry out RNA interference as a means of post-transcriptional
control.
●● mRNA
Answer: RNA that codes for protein
●● U2 or U4 snRNA
Answer: Spliceosome Ribozymes involved in mRNA processing
●● Genes that are active in all cell types are expected to be found in
constitutive heterochromatin regions of chromosomes.
Answer: False
●● Leucine zipper transcription regulators bind DNA with their repeated
leucine stretch.
Answer: False
●● Pentoses (5-carbon sugars) are significant in cells because
Answer: They are the sugar component of deoxyribonucleotides and
ribonucleotides.
●● Condensation reactions
