NURS 600 EXAM 3 QUESTIONS AND
ANSWERS WITH COMPLETE
SOLUTIONS ALREADY PASSED!!!
Question 1
How is Systemic Lupus Erythematosus (SLE) pathophysiologically defined, and
what broad structural tissues does it primarily target?
✔✔ SLE is a chronic, multi-system inflammatory autoimmune disorder. It
occurs when the body's immune system mistakenly attacks its own healthy
connective tissues, leading to widespread damage across multiple organ
systems, most notably within the skin and joints.
Question 2
Which demographic groups demonstrate the highest prevalence and incidence rates
for developing Systemic Lupus Erythematosus (SLE)?
✔✔ SLE is significantly more prevalent in female patients, who constitute
approximately 85% of all diagnosed cases. In the United States, there is a
notably higher incidence rate among young women of color.
Question 3
What are the classic systemic clinical findings, symptoms, and organ involvements
that a clinician should screen for when assessing a patient for suspected SLE?
✔✔ Common clinical indicators include profound fatigue, arthralgia (joint
pain), cutaneous rashes, neurological events (such as seizures), chest pain,
vasculitis, nephritis (kidney inflammation), unexplained weight loss, persistent
fevers, tachycardia, and generalized lymphadenopathy.
Question 4
What are the defining characteristics of Discoid Lupus Erythematosus (DLE),
where does its primary manifestation occur, and what external factor exacerbates
the condition?
✔✔ DLE is a localized form of lupus primarily confined to the skin,
characterized by chronic, scarring plaque-like rashes. It predominantly
,develops across the face, scalp, and torso, and is highly sensitive to and
aggravated by ultraviolet (UV) sun exposure.
Malar butterfly rash seen in:
SLE
SLE workup may include:
CBC, ESR, CRP, Gamma Globulins, ANA, RA, Anti-Smith, BUN/Creat, 24 hour
protein, IgG, IgM, Anti-beta 2 glycoprotein
Lupus nonpharmacologic management:
Heart health diet, modest exercise, avoidance of sun
Lupus pharmacologic management:
Omega-3
Steroids
NSAIDS
Hydrochloroquine
Monoclonal Antibody
Immunosuppressants
, Raynaud's disease
Peripheral arterial occlusive disease in which intermittent attacks are triggered by
cold or stress.
Raynaud's Disease
Reversible vasospastic disorder that affects the blood flow to the digits.
Raynaud's generally affects:
Females
(Often presents 15-45 years of age)
_______- Raynaud's Phenomenon:
No associated autoimmune disease. No autoantibodies present.
Primary
______ Raynaud's Phenomenon:
Associated with an autoimmune disease. (SLE, Scleroderma, mixed connective
tissue disease)
Secondary
CREST syndrome ("systemic sclerosis")
ANSWERS WITH COMPLETE
SOLUTIONS ALREADY PASSED!!!
Question 1
How is Systemic Lupus Erythematosus (SLE) pathophysiologically defined, and
what broad structural tissues does it primarily target?
✔✔ SLE is a chronic, multi-system inflammatory autoimmune disorder. It
occurs when the body's immune system mistakenly attacks its own healthy
connective tissues, leading to widespread damage across multiple organ
systems, most notably within the skin and joints.
Question 2
Which demographic groups demonstrate the highest prevalence and incidence rates
for developing Systemic Lupus Erythematosus (SLE)?
✔✔ SLE is significantly more prevalent in female patients, who constitute
approximately 85% of all diagnosed cases. In the United States, there is a
notably higher incidence rate among young women of color.
Question 3
What are the classic systemic clinical findings, symptoms, and organ involvements
that a clinician should screen for when assessing a patient for suspected SLE?
✔✔ Common clinical indicators include profound fatigue, arthralgia (joint
pain), cutaneous rashes, neurological events (such as seizures), chest pain,
vasculitis, nephritis (kidney inflammation), unexplained weight loss, persistent
fevers, tachycardia, and generalized lymphadenopathy.
Question 4
What are the defining characteristics of Discoid Lupus Erythematosus (DLE),
where does its primary manifestation occur, and what external factor exacerbates
the condition?
✔✔ DLE is a localized form of lupus primarily confined to the skin,
characterized by chronic, scarring plaque-like rashes. It predominantly
,develops across the face, scalp, and torso, and is highly sensitive to and
aggravated by ultraviolet (UV) sun exposure.
Malar butterfly rash seen in:
SLE
SLE workup may include:
CBC, ESR, CRP, Gamma Globulins, ANA, RA, Anti-Smith, BUN/Creat, 24 hour
protein, IgG, IgM, Anti-beta 2 glycoprotein
Lupus nonpharmacologic management:
Heart health diet, modest exercise, avoidance of sun
Lupus pharmacologic management:
Omega-3
Steroids
NSAIDS
Hydrochloroquine
Monoclonal Antibody
Immunosuppressants
, Raynaud's disease
Peripheral arterial occlusive disease in which intermittent attacks are triggered by
cold or stress.
Raynaud's Disease
Reversible vasospastic disorder that affects the blood flow to the digits.
Raynaud's generally affects:
Females
(Often presents 15-45 years of age)
_______- Raynaud's Phenomenon:
No associated autoimmune disease. No autoantibodies present.
Primary
______ Raynaud's Phenomenon:
Associated with an autoimmune disease. (SLE, Scleroderma, mixed connective
tissue disease)
Secondary
CREST syndrome ("systemic sclerosis")
