CHECK LATEST UPDATED 2026-
2027 ACTUAL FINAL EXAM PREP
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1. A patient is diagnosed with an X-linked dominant disorder. If the patient is
a woman, what is the probability she will transmit the disorder to her
offspring?
A) 0% of her offspring
B) 25% of her offspring
C) 50% of her offspring (male or female)
D) 100% of her male offspring only
Correct ,,,,answer,,,: C
Rationale: A woman with an X-linked dominant disorder will transmit the
affected X chromosome to 50% of her children, regardless of sex, because she has
two X chromosomes and passes one randomly .
,2. A researcher is studying the cellular response to stress. If a noxious
stimulus is unresolved, which pathway is activated to eliminate damaged
cells?
A) Necrosis
B) Autophagy
C) Apoptosis
D) Hyperplasia
Correct ,,,,answer,,,: C
Rationale: Apoptosis is programmed cell death. When a cell cannot recover from
an insult, it activates death signaling pathways to eliminate itself without causing
inflammation .
3. During a cardiac action potential, which phase involves the rapid reversal
of the membrane potential from negative to positive?
A) Hypopolarization
B) Repolarization
C) Depolarization
D) Overshoot
Correct ,,,,answer,,,: C
Rationale: Depolarization is characterized by the rapid influx of sodium ions,
causing the membrane potential to become less negative and "fire" .
4. A 55-year-old post-menopausal woman with hypertension complains of jaw
pain on heavy exertion. ECG shows normal sinus rhythm. What is the most
appropriate next diagnostic step?
,A) Echocardiogram
B) Exercise stress test
C) Cardiac catheterization
D) Myocardial perfusion imaging
Correct ,,,,answer,,,: B
Rationale: Jaw pain can be an angina equivalent. An exercise stress test evaluates
for ischemia under controlled conditions, especially when resting ECG is normal .
5. A 78-year-old female with a 120-pack-year smoking history complains of
hoarseness for several months. What pathology must be excluded?
A) Laryngitis
B) Hypothyroidism
C) Laryngeal cancer
D) Allergic rhinitis
Correct ,,,,answer,,,: C
Rationale: Hoarseness lasting >2 weeks, especially in a heavy smoker, is a red
flag for laryngeal cancer requiring visualization of the vocal cords .
6. Which of the following is the most common cause of heartburn-type
epigastric pain?
A) Peptic ulcer disease
B) Gastric cancer
C) GERD
D) Cholecystitis
, Correct ,,,,answer,,,: C
Rationale: GERD is the most common cause of heartburn. It results from the
reflux of gastric contents into the esophagus .
7. An infant presents with jaundice. Phototherapy is ordered. Which
diagnostic study is monitored to evaluate treatment effectiveness?
A) Direct Coombs test
B) Total serum bilirubin
C) Alanine aminotransferase (ALT)
D) White blood cell count
Correct ,,,,answer,,,: B
Rationale: Phototherapy converts bilirubin into water-soluble isomers that can be
excreted. Serum bilirubin levels are monitored to assess the need for continued or
escalated treatment .
8. An infant presents with sudden, severe abdominal pain, "red currant jelly"
stools, and a palpable abdominal mass. What is the initial treatment?
A) Appendectomy
B) Barium enema
C) IV antibiotics
D) Nasogastric decompression
Correct ,,,,answer,,,: B
Rationale: These symptoms indicate intussusception. A barium enema or air
enema is both diagnostic and therapeutic, as the pressure can reduce the
intussusception .