NSG 5003 Week 5 Knowledge Check: Complete
200-Question Final Exam Prep with Detailed
Rationales, Verified Answers, and
Comprehensive Pathophysiology Review for
Guaranteed A+ Success
🩺 Comprehensive NSG 5003 Practice Q&A
X-Linked Disorders & Genetics
1. A patient is diagnosed with an X-linked
dominant disorder. If the patient is a
woman, what is the probability she will
transmit the disorder to her offspring?
o A) 0% of her offspring
o B) 25% of her offspring
o C) 50% of her offspring (male or female)
o D) 100% of her male offspring only
o Correct ☑VERIFIED ANSWER: C
, o Rationale: A woman with an X-linked
dominant disorder will transmit the
affected X chromosome to 50% of her
children, regardless of sex, because she
has two X chromosomes and passes one
randomly .
2. A man inherits an autosomal recessive
disorder. His parents are both carriers.
What is the probability that his sibling will
be affected?
o A) 0%
o B) 25%
o C) 50%
o D) 100%
o Correct ☑VERIFIED ANSWER: B
o Rationale: In autosomal recessive
disorders, carriers have a 25% chance
, with each pregnancy of having an
affected child. The patient is affected,
but the sibling's risk is 1 in 4 .
3. Graves disease (hyperthyroidism) is an
example of which type II hypersensitivity
reaction?
o A) Modulation
o B) Antibody-dependent cell-mediated
cytotoxicity
o C) Neutrophil-mediated damage
o D) Complement-mediated lysis
o Correct ☑VERIFIED ANSWER: A
o Rationale: The antibody reacts with the
receptors on the target cell surface and
modulates the function of the receptor.
In Graves disease, autoantibody binds to
and activates receptors for thyroid-
, stimulating hormone (TSH), causing
hyperthyroidism .
Cellular Injury & Adaptation
4. A researcher is studying the cellular
response to stress. If a noxious stimulus is
unresolved, which pathway is activated to
eliminate damaged cells?
o A) Necrosis
o B) Autophagy
o C) Apoptosis
o D) Hyperplasia
o Correct ☑VERIFIED ANSWER: C
o Rationale: Apoptosis is programmed cell
death. When a cell cannot recover from
an insult, it activates death signaling
pathways to eliminate itself without
causing inflammation .
200-Question Final Exam Prep with Detailed
Rationales, Verified Answers, and
Comprehensive Pathophysiology Review for
Guaranteed A+ Success
🩺 Comprehensive NSG 5003 Practice Q&A
X-Linked Disorders & Genetics
1. A patient is diagnosed with an X-linked
dominant disorder. If the patient is a
woman, what is the probability she will
transmit the disorder to her offspring?
o A) 0% of her offspring
o B) 25% of her offspring
o C) 50% of her offspring (male or female)
o D) 100% of her male offspring only
o Correct ☑VERIFIED ANSWER: C
, o Rationale: A woman with an X-linked
dominant disorder will transmit the
affected X chromosome to 50% of her
children, regardless of sex, because she
has two X chromosomes and passes one
randomly .
2. A man inherits an autosomal recessive
disorder. His parents are both carriers.
What is the probability that his sibling will
be affected?
o A) 0%
o B) 25%
o C) 50%
o D) 100%
o Correct ☑VERIFIED ANSWER: B
o Rationale: In autosomal recessive
disorders, carriers have a 25% chance
, with each pregnancy of having an
affected child. The patient is affected,
but the sibling's risk is 1 in 4 .
3. Graves disease (hyperthyroidism) is an
example of which type II hypersensitivity
reaction?
o A) Modulation
o B) Antibody-dependent cell-mediated
cytotoxicity
o C) Neutrophil-mediated damage
o D) Complement-mediated lysis
o Correct ☑VERIFIED ANSWER: A
o Rationale: The antibody reacts with the
receptors on the target cell surface and
modulates the function of the receptor.
In Graves disease, autoantibody binds to
and activates receptors for thyroid-
, stimulating hormone (TSH), causing
hyperthyroidism .
Cellular Injury & Adaptation
4. A researcher is studying the cellular
response to stress. If a noxious stimulus is
unresolved, which pathway is activated to
eliminate damaged cells?
o A) Necrosis
o B) Autophagy
o C) Apoptosis
o D) Hyperplasia
o Correct ☑VERIFIED ANSWER: C
o Rationale: Apoptosis is programmed cell
death. When a cell cannot recover from
an insult, it activates death signaling
pathways to eliminate itself without
causing inflammation .
