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NRNP 6675/ NRNP6675 Midterm Exam (Latest 2026/2027 Update) | Complete Exam Questions with Verified Answers and Detailed Rationales | A+ Graded | Walden University

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INSTANT PDF DOWNLOAD - This is the comprehensive Midterm Exam study guide for NRNP 6675 PMHNP Care Across the Lifespan II at Walden University (Latest 2026/2027 Update), featuring 200+ verified exam questions with correct answers and detailed rationales . This resource covers SSRI mechanism of action (blockade of serotonin reuptake via SERT), the biopsychosocial model integrating biological/psychological/social factors, dopamine hypothesis in schizophrenia, limbic system structures (hippocampus for memory, amygdala for emotion/fear conditioning), H1 antagonism causing sedation, HPA axis dysregulation in MDD, CYP450 enzyme system genetics affecting psychotropic metabolism, atypical antipsychotics (olanzapine highest metabolic syndrome risk), the blood-brain barrier restricting large/polar molecules, PHQ-9 scoring for MDD severity (20-27 severe), first-line antidepressants SSRIs/SNRIs, bupropion seizure risk (lowest threshold, 450 mg/day), duloxetine for MDD with chronic pain, valproic acid neural tube defects, lithium therapeutic range, neuroleptic malignant syndrome (hyperthermia/rigidity/autonomic instability/elevated CK), cluster B personality disorders (antisocial, borderline, histrionic, narcissistic), and NP core competencies for independent practice . INSTANT DIGITAL DOWNLOAD (PDF) immediately upon purchase. Fully text-searchable, printable, and accessible anytime. Trusted by Walden University PMHNP students for Midterm Exam success. 100% satisfaction guarantee. Vertical Keywords / Tags NRNP 6675 Midterm Exam Walden PMHNP Care Across the Lifespan II Midterm SSRI mechanism serotonin reuptake inhibition SERT Biopsychosocial model biological psychological social factors Dopamine hypothesis schizophrenia excess subcortical dopamine Amygdala fear conditioning emotional processing Hippocampus memory formation limbic system H1 antagonist sedation weight gain HPA axis dysregulation major depressive disorder hypercortisolism CYP450 enzymes 2D6 3A4 2C19 psychotropic metabolism Olanzapine highest risk metabolic syndrome weight gain diabetes Blood brain barrier restricts hydrophilic large molecules PHQ 9 severe depression score 20 to 27 First line MDD treatment SSRIs SNRIs Bupropion seizure risk threshold lowering 450 mg day Duloxetine MDD with chronic pain Valproic acid neural tube defects pregnancy category D Lithium therapeutic range 0.6 to 1.2 mEq L Neuroleptic malignant syndrome rigidity fever elevated CK Cluster B personality disorders antisocial borderline histrionic narcissistic Non maleficence obligation not inflict harm Respect for autonomy patient right make choices Dependent personality disorder subordinate needs lack self confidence Munchausen syndrome by proxy caretaker fabricates illness child Health literacy access process utilize health information Akathisia motor restlessness inability remain still Wernicke encephalopathy ocular abnormalities nystagmus thiamine deficiency Walden University PMHNP Midterm 2026 A+ Grade NRNP 6675 Study Guide

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Walden University




A&Q 5766 PNRN
W

College of Nursing · PMHNP Program
PMHNP
E D U C AT I O N F O R G O O D · P O S I T I V E S O C I A L C H A N G E
EST. 1970




NRNP 6675 Midterm Exam Questions & Answers 2025/2026
P SYC H I AT R I C M E N TA L H E A LT H N U R S E P R A C T I T I O N E R · CO M P R E H E N S I V E ST U DY F L A S H C A R D S E T

INSTITUTION Walden University COURSE CODE NRNP 6675
PROGRAM MSN · Psychiatric Mental Health Nurse ACADEMIC YEAR
Practitioner (PMHNP)
EXAM TITLE NRNP 6675 Midterm — Questions & Answers TOTAL QUESTIONS 45 Questions
Study Guide
COURSE TITLE PMHNP Care Across the Lifespan I: FORMAT Multiple Choice — Flash Card Style
Psychopathology & Psychopharmacology Term/Definition with Rationales


STUDY GUIDE INSTRUCTIONS
▸ Each question presents a term, concept, or definition followed by multiple-choice answer options.
▸ Select the single best answer based on NRNP 6675 PMHNP curriculum content.
▸ Topics span psychopathology, DSM-5 diagnostic criteria, psychopharmacology, personality disorders, neurobiology, and PMHNP
professional practice.
▸ Correct answers and detailed clinical/academic rationales appear below each question for comprehensive exam preparation.


PSYCHOPATHOLOGY, PSYCHOPHARMACOLOGY, PERSONALITY DISORDERS & Questions
PMHNP PROFESSIONAL PRACTICE 1 – 45

1. Substance intoxication is best defined as:
A. A chronic pattern of substance use causing impairment or distress
B. A syndrome from recent ingestion or exposure to a substance
C. Symptoms occurring upon cessation or reduction of substance use
D. A genetic predisposition to substance dependence
CORRECT ANSWER B. A syndrome from recent ingestion or exposure to a substance

RATIONALE DSM-5 defines substance intoxication as a reversible substance-specific syndrome caused by recent ingestion of or
exposure to a substance, with clinically significant problematic behavioral or psychological changes. Option A
describes substance use disorder. Option C describes substance withdrawal. The syndrome is directly temporally
linked to recent substance exposure.

,2. Tardive dyskinesia is characterized by:
A. Motor restlessness and inability to remain still
B. Sustained muscle contractions causing abnormal postures
C. Abnormal involuntary movements affecting face, mouth, and tongue
D. Acute dystonic reaction with oculogyric crisis
CORRECT ANSWER C. Abnormal involuntary movements affecting face, mouth, and tongue

RATIONALE TD is a late-onset, potentially irreversible movement disorder from long-term antipsychotic use, featuring
rhythmic involuntary movements of the face (grimacing), mouth (lip smacking, tongue protrusion), and jaw.
Option A describes akathisia. Option B describes dystonia. Option D describes an acute dystonic reaction—all
distinct from the chronic rhythmic nature of TD.


3. Delusional disorder is defined as:
A. A deeply held belief lasting at least one month without prominent hallucinations
B. A psychotic disorder with multiple bizarre delusions and auditory hallucinations
C. A brief psychotic episode lasting less than one month
D. A mood disorder with psychotic features during manic episodes
CORRECT ANSWER A. A deeply held belief lasting at least one month without prominent hallucinations

RATIONALE Delusional disorder requires one or more delusions persisting ≥1 month, with functioning impaired only in
relation to the delusional theme, and no prominent hallucinations, disorganized speech, grossly disorganized
behavior, or negative symptoms. Option B describes schizophrenia. Option C describes brief psychotic disorder.
Option D describes bipolar I with psychotic features.


4. Which statement about preoccupation with castration is true?
A. It is always consistent with transvestic disorder
B. It can be serious and life-threatening if castration is carried out without medical supervision
C. It is pathognomonic for sexual masochism disorder
D. It is always benign and requires no clinical attention
CORRECT ANSWER B. It can be serious and life-threatening if castration is carried out without medical supervision

RATIONALE When associated with gender dysphoria or body integrity identity disorder, castration preoccupation can lead to
self-surgery or unlicensed practitioners, risking hemorrhage, infection, and death. It is NOT pathognomonic for
transvestic disorder, sexual masochism, or any single diagnosis. The life-threatening risk when performed outside
medical settings is the paramount clinical concern.

, 5. CPT (Current Procedural Terminology) is best described as:
A. A system for classifying mental disorders
B. A federal privacy regulation for health information
C. A system for describing medical and surgical procedures
D. A diagnostic coding system for inpatient hospital stays
CORRECT ANSWER C. A system for describing medical and surgical procedures

RATIONALE CPT, maintained by the AMA, provides standardized nomenclature for medical, surgical, and diagnostic services—
essential for billing and reimbursement. Option A describes DSM-5. Option B describes HIPAA. Option D describes
DRGs. PMHNPs use CPT codes daily for documenting evaluation/management and psychotherapy services.


6. A patient on chlorpromazine (Thorazine) reports dry orgasm with subsequent milky urine. The PMHNP recognizes this
as:
A. A medical emergency requiring immediate urology referral
B. May be a harmless response to the medication
C. Pathognomonic for prostate malignancy
D. Evidence of medication diversion
CORRECT ANSWER B. May be a harmless response to the medication

RATIONALE Retrograde ejaculation—semen entering the bladder due to alpha-1 blockade at the bladder neck—is a known
side effect of chlorpromazine and other antipsychotics. Dry orgasm followed by cloudy urine results. While
bothersome, it is generally benign and reversible upon dose reduction or discontinuation. It is not a urologic
emergency, cancer indicator, or sign of diversion.


7. Turner's syndrome results from:
A. Trisomy of chromosome 21
B. Absence of second female sex chromosome (XO)
C. Extra X chromosome in males (XXY)
D. Deletion on the short arm of chromosome 5
CORRECT ANSWER B. Absence of second female sex chromosome (XO)

RATIONALE Turner's syndrome (45,X) is caused by complete or partial absence of one X chromosome in females, resulting in
the XO karyotype. Features include short stature, webbed neck, cubitus valgus, infertility, and cardiac anomalies.
Treatment involves growth hormone and estrogen replacement. Option A is Down syndrome (trisomy 21). Option
C is Klinefelter syndrome (47,XXY).

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