Pathophysiology 2 Exam 4
Study online at https://quizlet.com/_jo52l3
1. Describe the function Make new bones to maintain skeletal structures
of osteoblasts in bone
remodeling?
2. Describe the function Degrades bones to initiate bone remodeling
of osteoclasts in bone
remodeling?
3. What is osteomyelitis? Severe pyogenic (pus producing) infection of the bone & local tissue due to
organisms
4. What are the ways in - Bloodstream
which organisms can - Adjacent soft tissue
reach the bone? - Direct introduction of organism
5. Osteomyelitis result- - Burns
ing from organ- - Sinus disease
ism reaching bone - Trauma
through adjacent tis- - Malignant tumor necrosis
sue is caused by? - Periodontal infection
- Infected pressure ulcer (bedsores)
6. Osteomyelitis result- - Open fracture
ing from a direct in- - Penetrating wound
troduction of an or- - Surgical contamination
ganism is caused by? - Insertion of protheses
- Metal plates
- Screws
7. Clinical manifestation - Fever- Malaise
of osteomyelitis in - Anorexia/ weight loss
adults? - Night sweats
1/9
, Pathophysiology 2 Exam 4
Study online at https://quizlet.com/_jo52l3
8. Clinical manifestation - High fever & pain
of osteomyelitis in - Redness & swelling at the site of bone involvement
children? - Brodie abscess: subacute osteomyelitis
9. What happens when Necrotic bone separates from healthy bone into dead segments leading to
osteomyelitis is not sequestra and then chronic osteomyelitis
managed or treat- - Abscess or chronic infection may occur
ment is insufficient?
10. What possible issue It could prevent successful effects of antibiotics when treating osteomyelitis
could arise w/ an in-
volucrum?
11. Why may stopping If the treatment is stopped before the course is finished (4-6 weeks)
antibiotic treatment then this can cause sequestra (necrosis of the bone) causing chronic os-
for osteomyelitis too teomyelitis which is hard to treat since antibiotic cannot reach this area
soon worsen your
conditions?
12. For children, where The metaphysis of the long bone b/c it is rich in red marrow
does osteomyelitis
occur & why?
13. Why is articular carti- B/c it has limited capacity to heal itself as there are no blood vessel present
lage particularly sus- in the cartilage
ceptible to degenera-
tive changes?
14. What manufactures Chondrocytes
the organic compo-
nent of the matrix
composed of a net-
work of collagen fib-
2/9
Study online at https://quizlet.com/_jo52l3
1. Describe the function Make new bones to maintain skeletal structures
of osteoblasts in bone
remodeling?
2. Describe the function Degrades bones to initiate bone remodeling
of osteoclasts in bone
remodeling?
3. What is osteomyelitis? Severe pyogenic (pus producing) infection of the bone & local tissue due to
organisms
4. What are the ways in - Bloodstream
which organisms can - Adjacent soft tissue
reach the bone? - Direct introduction of organism
5. Osteomyelitis result- - Burns
ing from organ- - Sinus disease
ism reaching bone - Trauma
through adjacent tis- - Malignant tumor necrosis
sue is caused by? - Periodontal infection
- Infected pressure ulcer (bedsores)
6. Osteomyelitis result- - Open fracture
ing from a direct in- - Penetrating wound
troduction of an or- - Surgical contamination
ganism is caused by? - Insertion of protheses
- Metal plates
- Screws
7. Clinical manifestation - Fever- Malaise
of osteomyelitis in - Anorexia/ weight loss
adults? - Night sweats
1/9
, Pathophysiology 2 Exam 4
Study online at https://quizlet.com/_jo52l3
8. Clinical manifestation - High fever & pain
of osteomyelitis in - Redness & swelling at the site of bone involvement
children? - Brodie abscess: subacute osteomyelitis
9. What happens when Necrotic bone separates from healthy bone into dead segments leading to
osteomyelitis is not sequestra and then chronic osteomyelitis
managed or treat- - Abscess or chronic infection may occur
ment is insufficient?
10. What possible issue It could prevent successful effects of antibiotics when treating osteomyelitis
could arise w/ an in-
volucrum?
11. Why may stopping If the treatment is stopped before the course is finished (4-6 weeks)
antibiotic treatment then this can cause sequestra (necrosis of the bone) causing chronic os-
for osteomyelitis too teomyelitis which is hard to treat since antibiotic cannot reach this area
soon worsen your
conditions?
12. For children, where The metaphysis of the long bone b/c it is rich in red marrow
does osteomyelitis
occur & why?
13. Why is articular carti- B/c it has limited capacity to heal itself as there are no blood vessel present
lage particularly sus- in the cartilage
ceptible to degenera-
tive changes?
14. What manufactures Chondrocytes
the organic compo-
nent of the matrix
composed of a net-
work of collagen fib-
2/9
