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PACKAGE
Opioid agonists Select Prototype Medication - CORRECT ANSWERS-Morphine
Opioid Agonist Other medications - CORRECT ANSWERS-Fentanyl
Meperidine
Methadone
Codeine
Oxycodone
Hydromorphone
Purpose for Opioid Agonist Medications - CORRECT ANSWERS-act on the mu
receptors and, to a lesser degree, on kappa receptors. Activation of mu
receptors produces analgesia, respiratory depression, euphoria, and sedation,
whereas kappa receptor activation produces analgesia, sedation, and decreased
GI motility. Activation of mu receptors can also be linked to physical
dependence.
Opioid classifications - CORRECT ANSWERS-agonists, agonist-antagonists, and
antagonists
Opioid agonist - CORRECT ANSWERS-attaches to a receptor and produces a
response (analgesia, euphoria, sedation, respiratory depression, and other
effects)
, opioid agonist-antagonist - CORRECT ANSWERS-causes an analgesic response when
administered alone and prevents an analgesic response when administered with
a pure agonist
opioid antagonist - CORRECT ANSWERS-does not produce analgesia or any other
effects of opioids. Its main use is to reverse respiratory and CNS depression
caused by overdose of opioids.
Antiemetic prototype medications - CORRECT ANSWERS-Glucocorticoids:
Dexamethasone
Substance P/neurokinin1 antagonists: Aprepitant
Serotonin antagonists: Ondansetron, granisetron
Dopamine antagonists: Prochlorperazine, metoclopramide, promethazine
Cannabinoids: Dronabinol
Anticholinergics: Scopolamine
Antihistamines: Dimenhydrinate, hydroxyzine
Benzodiazepines: Lorazepam
Adverse Medication Effects: Anticholinergic - CORRECT ANSWERS-Effects that are a
result of muscarinic receptor blockade.
Most are seen in eyes, smooth muscle, exocrine glands, and the heart
Adverse Medication Effects: Cardiovascular - CORRECT ANSWERS-Can involve blood
vessels and the heart.
Antihypertensives can cause orthostatic hypotension