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1. Definition of Pathophys- defined as not only the cellular and organ changes that occur with
iology disease, but also the effects that these changes have on total body
function.
2. 5 etiologic factors and Biological: bacteria and viruses
an example of each Physical: trauma, burns, and radiation
Chemical: poisons, drugs
One's genetic inheritance
Nutritional excesses or deficiencies
3. 2 types of risk factors congenital factors (present at birth) or acquired (occurring after birth)
4. Difference between Morphology - fundamental structure or form of cells or tissues (includes
morphology and histol- the gross and microscopic changes)
ogy Histology - study of the cells and extracellular matrix of body tissues (at
the tissue level)
5. Signs and symptoms Signs - objective and can be seen or measured. Elevated temp, leg
edema, and changes in pupil size.
symptoms - subjective. pain, trouble breathing, dizziness.
6. 3 important processes Patient history, physical examination, and diagnostic tests.
when coming to a diag-
nosis?
7. Validity, reliability, sensi- Validity - how a tool measure what it is intended to measure.
tivity, and specificity def-
initions. Reliability - likelihood the same result occurring with multiple testing.
Sensitivity - the proportion of people with a disease who are positive for
that disease.
Specificity - are people without the disease who are negative on a given
test.
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, Portage Pathophysiology Exam 1
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8. Define epidemiology Epidemiology is the study of disease occurrence in human populations.
and name some thing It tracks, age, race, dietary habits, lifestyle, or geographic location.
that it tracks.
9. Difference between inci- Incidence - the number of new cases in a population
dence and prevalence
Prevalence - the number of people with the disease in a population in a
given time
10. Define Mortality and Mortality - the statistics that deal with cause of death in a population
Morbidity
Morbidity is the effect of illness on one's life.
11. Define Primary, sec- Primary: remove risk factors to prevent disease from occurring. Exam-
ondary, and tertiary pre- ples - yearly check up, daily vitamin, vaccination, wearing seatbelts or
vention and give an ex- helmets.
ample of each.
Secondary: detect and treat disease early, usually while the disease is
asymptomatic and curable. Example - pap smears, checking bp and
cholesterol and colonoscopy screening. Usually all done by setting of a
physician.
Tertiary: occurs after a diagnosis has been made and clinical interven-
tions are needed to reduce complications.
12. Why is evidence based Evidence-based practice is the conscientious, explicit, and judicious use
practice important? of current best evidence in making decisions about the care of individual
patients. This is to counteract "the way things have always been done,"
and to practice based on clinical research.
13. what are the 3 primary Nucleus, cytoplasm, and plasma membrane
structures of the cell?
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