Chamberlain NR283 Pathophysiology Master Test 1 2
3 4 Bank: 150 Comprehensive Practice Questions
This high-yield DocMerit practice test bank features 150 comprehensive multiple-choice
questions custom-built for Chamberlain University’s NR283 Pathophysiology
curriculum. The resource spans foundational cellular mechanisms, fluid and electrolyte
imbalances, and advanced multi-system disorders across Exam 1, 2, 3, and the
cumulative Final Exam. Every question provides the correct answer in bold alongside
a meticulous, italicized rationale to bridge knowledge gaps and secure top-tier exam
scores.
Pathophysiology (NR283) Exam Master Question Bank
Cellular Biology, Injury, and Adaptation
1. A patient's tissue biopsy reports a decrease in cellular size due to a loss of
subcellular components. How should the nurse document this adaptive change?
A. Hypertrophy
B. Hyperplasia
C. Atrophy
D. Metaplasia
Rationale: Atrophy is a decrease in cellular size and functional capacity caused by
factors like disuse, denervation, or decreased blood flow. Hypertrophy refers to
increased cell size, hyperplasia is an increased number of cells, and metaplasia is the
replacement of one mature cell type with another.
2. A pathologist notes that cells in a biopsy from a smoker's airway have
transformed from ciliated columnar epithelial cells to stratified squamous
epithelial cells. This is an example of:
A. Dysplasia
B. Metaplasia
C. Anaplasia
D. Aplasia
Rationale: Metaplasia occurs when a chronic stressor or irritant causes one mature cell
type to be replaced by another mature cell type that is better able to withstand the
environment. Dysplasia represents abnormal, disordered growth and is pre-cancerous,
while anaplasia indicates a lack of cellular differentiation.
3. During a myocardial infarction, lack of oxygen leads to a decrease in cellular
ATP production. Which cellular consequence occurs next?
A. Sodium exits the cell rapidly
3 4 Bank: 150 Comprehensive Practice Questions
This high-yield DocMerit practice test bank features 150 comprehensive multiple-choice
questions custom-built for Chamberlain University’s NR283 Pathophysiology
curriculum. The resource spans foundational cellular mechanisms, fluid and electrolyte
imbalances, and advanced multi-system disorders across Exam 1, 2, 3, and the
cumulative Final Exam. Every question provides the correct answer in bold alongside
a meticulous, italicized rationale to bridge knowledge gaps and secure top-tier exam
scores.
Pathophysiology (NR283) Exam Master Question Bank
Cellular Biology, Injury, and Adaptation
1. A patient's tissue biopsy reports a decrease in cellular size due to a loss of
subcellular components. How should the nurse document this adaptive change?
A. Hypertrophy
B. Hyperplasia
C. Atrophy
D. Metaplasia
Rationale: Atrophy is a decrease in cellular size and functional capacity caused by
factors like disuse, denervation, or decreased blood flow. Hypertrophy refers to
increased cell size, hyperplasia is an increased number of cells, and metaplasia is the
replacement of one mature cell type with another.
2. A pathologist notes that cells in a biopsy from a smoker's airway have
transformed from ciliated columnar epithelial cells to stratified squamous
epithelial cells. This is an example of:
A. Dysplasia
B. Metaplasia
C. Anaplasia
D. Aplasia
Rationale: Metaplasia occurs when a chronic stressor or irritant causes one mature cell
type to be replaced by another mature cell type that is better able to withstand the
environment. Dysplasia represents abnormal, disordered growth and is pre-cancerous,
while anaplasia indicates a lack of cellular differentiation.
3. During a myocardial infarction, lack of oxygen leads to a decrease in cellular
ATP production. Which cellular consequence occurs next?
A. Sodium exits the cell rapidly
