Renal System
Pathophysiology
,Learning Objectives:
• Describe the pathogenesis of renal disorders and injury.
• Describe the manifestation of renal disorders and injury.
• Describe the complications and variations of renal disorders and injury.
Evidence Statement: The learner identifies common characteristics of urinary infections (e.g., pyelonephritis,
glomerulonephritis, renal calculi [uroliths or kidney stones]).
Evidence Statement: The learner identifies common characteristics of end-stage renal disease.
Evidence Statement: The learner identifies common characteristics of dialysis, hemodialysis, and continuous
renal replacement therapy (CRRT).
Evidence Statement: The learner identifies common characteristics of urinary malignancies (e.g., bladder,
renal cell carcinoma, or kidney cancer).
,Functions of the kidney:
• Balancing solutes and water transport
• Excreting metabolic waste products
• Conserving nutrients
• Regulating acid/base balance
• Secreting renin
• Activating vitamin D
• Performing gluconeogenesis
• Secreting erythropoietin
https://courses.lumenlearning.com/suny-ap2/chapter/gross-anatomy-of-the-kidney/
, Path of blood
through the
kidney
1) Renal artery – supplies blood to the kidney
2) Afferent Arteriole – supplies blood to glomerulus
3) Glomerular Capillaries – filter blood, retain proteins and
RBCs, excrete H20, electrolytes, AAs, glucose, etc.
4) Efferent Arteriole – empties blood from the glomerulus
5) Peritubular capillaries – water and solute reabsorption,
blood supply for kidney
6) Renal veins – empties blood from the kidney
https://courses.lumenlearning.com/suny-ap2/chapter/gross-anatomy-of-the-kidney/
Pathophysiology
,Learning Objectives:
• Describe the pathogenesis of renal disorders and injury.
• Describe the manifestation of renal disorders and injury.
• Describe the complications and variations of renal disorders and injury.
Evidence Statement: The learner identifies common characteristics of urinary infections (e.g., pyelonephritis,
glomerulonephritis, renal calculi [uroliths or kidney stones]).
Evidence Statement: The learner identifies common characteristics of end-stage renal disease.
Evidence Statement: The learner identifies common characteristics of dialysis, hemodialysis, and continuous
renal replacement therapy (CRRT).
Evidence Statement: The learner identifies common characteristics of urinary malignancies (e.g., bladder,
renal cell carcinoma, or kidney cancer).
,Functions of the kidney:
• Balancing solutes and water transport
• Excreting metabolic waste products
• Conserving nutrients
• Regulating acid/base balance
• Secreting renin
• Activating vitamin D
• Performing gluconeogenesis
• Secreting erythropoietin
https://courses.lumenlearning.com/suny-ap2/chapter/gross-anatomy-of-the-kidney/
, Path of blood
through the
kidney
1) Renal artery – supplies blood to the kidney
2) Afferent Arteriole – supplies blood to glomerulus
3) Glomerular Capillaries – filter blood, retain proteins and
RBCs, excrete H20, electrolytes, AAs, glucose, etc.
4) Efferent Arteriole – empties blood from the glomerulus
5) Peritubular capillaries – water and solute reabsorption,
blood supply for kidney
6) Renal veins – empties blood from the kidney
https://courses.lumenlearning.com/suny-ap2/chapter/gross-anatomy-of-the-kidney/