NU 327 Pathophysiology Exam 1 |Study
Questions and Answers |2026 Update
Chronic Myeloid Leukemias (CML) -Correct Answer ✔-Overproduction of
Granulocytes carrying the Philadelphia chromosome.
Onset is 40-50 years old, survival rate about 2 years after diagnosis. LA- 50%
survival
Acute Myeloid Leukemia (AML) -Correct Answer ✔-80% of all adult leukemia,
frequent infections esp. skin, GI, GU, & resp. tract.
LA 40-50% for children
LA 20-30% in adults
Chronic Lymphoid Leukemias (CLL) -Correct Answer ✔-Usually due to malignant b-
cell precursor that invades lymphoid tissue & bone marrow ⇒ prolonged
apoptosis
Usually die with disease. Onset 60-70 years old
Acute Lymphoblastic Leukemias / Lymphomas -Correct Answer ✔-Majority are
malignant lymphoblastic leukemia
Common in children (Best survival rate)
LA 85% kids and 30-50% adults
, Acute Lymphoblastic Leukemias / Lymphomas -Correct Answer ✔-Bone pain,
bruising, fever, abdominal pain, activity avoidance.
Plasma Cell Myeloma (Multiple Myeloma) -Correct Answer ✔-Malignancy of b-
cells ⇒ increase in antibody fragments called Bence Jones proteins
Multiple Tumor sites: bone, liver, spleen, kidneys, lymph nodes
Slow onset
Higher incidence in males
Onset starts at 40 years
Plasma Cell Myeloma (Multiple Myeloma) -Correct Answer ✔-Most (insidious
onset) are associated w/deposition of the antibody fragments in the bone and
kidneys.
High Ca++ in blood & urine, renal failure (calcium deposits in kidneys),
honeycomb bone, bone pain, fractures
Hodgkin's Disease -Correct Answer ✔-Malignancies of lymph nodes that produce
Reed Sternberg cells from b-cells in association w/
90% survival at 10 years.
Most common in males
Onset between 20-40 years
Hodgkin's Disease -Correct Answer ✔-Epstein-Barr Virus.
Predictable metastatic pattern
Slow progress
Questions and Answers |2026 Update
Chronic Myeloid Leukemias (CML) -Correct Answer ✔-Overproduction of
Granulocytes carrying the Philadelphia chromosome.
Onset is 40-50 years old, survival rate about 2 years after diagnosis. LA- 50%
survival
Acute Myeloid Leukemia (AML) -Correct Answer ✔-80% of all adult leukemia,
frequent infections esp. skin, GI, GU, & resp. tract.
LA 40-50% for children
LA 20-30% in adults
Chronic Lymphoid Leukemias (CLL) -Correct Answer ✔-Usually due to malignant b-
cell precursor that invades lymphoid tissue & bone marrow ⇒ prolonged
apoptosis
Usually die with disease. Onset 60-70 years old
Acute Lymphoblastic Leukemias / Lymphomas -Correct Answer ✔-Majority are
malignant lymphoblastic leukemia
Common in children (Best survival rate)
LA 85% kids and 30-50% adults
, Acute Lymphoblastic Leukemias / Lymphomas -Correct Answer ✔-Bone pain,
bruising, fever, abdominal pain, activity avoidance.
Plasma Cell Myeloma (Multiple Myeloma) -Correct Answer ✔-Malignancy of b-
cells ⇒ increase in antibody fragments called Bence Jones proteins
Multiple Tumor sites: bone, liver, spleen, kidneys, lymph nodes
Slow onset
Higher incidence in males
Onset starts at 40 years
Plasma Cell Myeloma (Multiple Myeloma) -Correct Answer ✔-Most (insidious
onset) are associated w/deposition of the antibody fragments in the bone and
kidneys.
High Ca++ in blood & urine, renal failure (calcium deposits in kidneys),
honeycomb bone, bone pain, fractures
Hodgkin's Disease -Correct Answer ✔-Malignancies of lymph nodes that produce
Reed Sternberg cells from b-cells in association w/
90% survival at 10 years.
Most common in males
Onset between 20-40 years
Hodgkin's Disease -Correct Answer ✔-Epstein-Barr Virus.
Predictable metastatic pattern
Slow progress
