MIDTERM NR566 ACTUAL EXAM QUESTIONS
AND ANSWERS 2026 VERIFIED
COMPREHENSIVE STUDY GUIDE
◉ How does Phentermine and Diethylpropion promote weight loss?
Answer: -Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress
appetite by increasing the availability of norepinephrine at receptors
in the brain
◉ What is the maximum recommended duration of use for non-
amphetamines? Answer: 3 months or less
◉ What drug schedule are Phentermine and Diethylpropion under?
Answer: Schedule IV
◉ What labs should be monitored with Phentermine and
Diethylpropion? What condition should we screen for? Answer: -
baseline CMP (watch electrolytes and creatinine)
-screen for depression
◉ Phentermine adverse effects Answer: -increase HR and BP
-dry mouth and constipation
,◉ What is role of topiramate in weight loss? Answer: Increases
satiety
◉ What are some Phentermine/topiramate contraindications for
use? Answer: not approved in children and contraindicated with
severe hepatic impairment
◉ How should we educate patient to take Phentermine/topiramate
to avoid insomnia? Answer: given before 1600
◉ What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution? Answer: hx drug abuse,
glaucoma, pregnant, HTN, hyperthyroidism
◉ Phentermine/topiramate adverse effects Answer: insomnia,
nervousness, anxiety, depression, blurred vision
◉ Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply. Answer: A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
,F) A, B, E
ANSWER: A,C,D
◉ Orlistat is a lipase inhibitor that acts on the _________ and reduces
absorption of fat by 30%. Answer: GI tract
◉ Take multivitamin ___hours before/after to supplement fat-soluble
vitamins that may not be absorbed well when taking Orlistat.
Answer: 2
◉ Orlistat is OTC as 60 mg TID with meals. Not approved in children
<____. Answer: 12
◉ Orlistat results in the least amount of weight loss of all. How
much? Answer: 2-3% body weight (7 lbs in year)
◉ Orlistat adverse effects Answer: Fecal incontinence, oily rectal
leakage, flatus, abdominal cramps. liver damage (light-colored
stools, dark urine, fatigue, jaundice, anorexia)
◉ When is Orlistat contraindicated? Answer: In those with
malabsorption syndrome or cholestasis
, ◉ What vitamin deficiency are we concerned about when taking
Orlistat...especially if the patient is on coumadin? Answer: Monitor
Coumadin as Vitamin K deficiency may occur and intensify effect of
Coumadin.
◉ A patient with a BMI of 27 would be considered: Answer:
overweight
◉ Lorcaserin adverse effects Answer: headache, URI, back pain,
hypoglycemia (in DM), blood dyscrasias, cognitive impairment,
psychiatric disorders, priapism, pulmonary hypertension, and
valvular heart disease
◉ Lorcaserin MOA Answer: Reduces waist circumference, fasting
glucose, insulin, total cholesterol, LDL, triglycerides
◉ When is Lorcaserin contraindicated? Answer: CrCl <30
-Not approved in children
◉ Lorcaserin drug interactions Answer: -MAOI inhibitors, SSRIs,
SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
AND ANSWERS 2026 VERIFIED
COMPREHENSIVE STUDY GUIDE
◉ How does Phentermine and Diethylpropion promote weight loss?
Answer: -Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress
appetite by increasing the availability of norepinephrine at receptors
in the brain
◉ What is the maximum recommended duration of use for non-
amphetamines? Answer: 3 months or less
◉ What drug schedule are Phentermine and Diethylpropion under?
Answer: Schedule IV
◉ What labs should be monitored with Phentermine and
Diethylpropion? What condition should we screen for? Answer: -
baseline CMP (watch electrolytes and creatinine)
-screen for depression
◉ Phentermine adverse effects Answer: -increase HR and BP
-dry mouth and constipation
,◉ What is role of topiramate in weight loss? Answer: Increases
satiety
◉ What are some Phentermine/topiramate contraindications for
use? Answer: not approved in children and contraindicated with
severe hepatic impairment
◉ How should we educate patient to take Phentermine/topiramate
to avoid insomnia? Answer: given before 1600
◉ What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution? Answer: hx drug abuse,
glaucoma, pregnant, HTN, hyperthyroidism
◉ Phentermine/topiramate adverse effects Answer: insomnia,
nervousness, anxiety, depression, blurred vision
◉ Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply. Answer: A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
,F) A, B, E
ANSWER: A,C,D
◉ Orlistat is a lipase inhibitor that acts on the _________ and reduces
absorption of fat by 30%. Answer: GI tract
◉ Take multivitamin ___hours before/after to supplement fat-soluble
vitamins that may not be absorbed well when taking Orlistat.
Answer: 2
◉ Orlistat is OTC as 60 mg TID with meals. Not approved in children
<____. Answer: 12
◉ Orlistat results in the least amount of weight loss of all. How
much? Answer: 2-3% body weight (7 lbs in year)
◉ Orlistat adverse effects Answer: Fecal incontinence, oily rectal
leakage, flatus, abdominal cramps. liver damage (light-colored
stools, dark urine, fatigue, jaundice, anorexia)
◉ When is Orlistat contraindicated? Answer: In those with
malabsorption syndrome or cholestasis
, ◉ What vitamin deficiency are we concerned about when taking
Orlistat...especially if the patient is on coumadin? Answer: Monitor
Coumadin as Vitamin K deficiency may occur and intensify effect of
Coumadin.
◉ A patient with a BMI of 27 would be considered: Answer:
overweight
◉ Lorcaserin adverse effects Answer: headache, URI, back pain,
hypoglycemia (in DM), blood dyscrasias, cognitive impairment,
psychiatric disorders, priapism, pulmonary hypertension, and
valvular heart disease
◉ Lorcaserin MOA Answer: Reduces waist circumference, fasting
glucose, insulin, total cholesterol, LDL, triglycerides
◉ When is Lorcaserin contraindicated? Answer: CrCl <30
-Not approved in children
◉ Lorcaserin drug interactions Answer: -MAOI inhibitors, SSRIs,
SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
