PM Quizlet
140 Must Know NCLEX Meds 2026-2027 | Class,
Indication, Action & Nursing Considerations | Alteplase,
Atorvastatin, Digoxin, Warfarin & More | NCSBN
Exam Prep
Alteplase (t-PA)
class: thrombolytics
Indication: MI, acute ischemic stroke, occluded central lines
Action: converts plasminogen to plasmin which degrades the fibrin found
Nursing Considerations:
- contraindicated in active bleeding
-monitor for anaphylaxis
- use caution with uncontrolled hypertension
Atorvastatin (Lipitor)
class: lipid-lowering agent
Indication: management of high cholesterol (hypercholesterolemia), primary
prevention of cardiovascular disease
Action: lowers total cholesterol as well as LDL while slightly increasing
HDL. Inhibits HMG-CoA reductase which plays a role in the liver in
cholesterol formation
Nursing Considerations
- contraindicated in active liver disease
- may cause rhabdomyolysis
- monitor serum cholesterol
- monitor liver function tests, renal function
Acetaminophen (Tylenol)
class: antipyretic, non-opioid analgesic
Indication: pain, fever
Action: inhibit the synthesis of prostaglandins which play a role in transmission
of pain signals and fever response
Nursing Considerations:
- do not exceed 4g of acetaminophen per day
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PM - overdose will lead to hepatotoxicity
Quizlet
- *Acetadote*is the antidote for overdose
- may increase risk for bleed with warfarin therapy
Acyclovir (Zovirax)
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PM Quizlet
class: antiviral, purine analogues
Indication:genital herpes, herpes zoster, chicken pox
Action: interferes with viral DNA synthesis
Nursing Considerations:
- may cause seizures, renal failure, Stevens-Johnson syndrome,
thrombotic thrombocytopenic purpura syndrome, diarrhea,
dizziness, nausea
- monitor renal function
- assess lesions
- instruct patient to use proper protection during sexual intercourse
Albuterol (Proventil)
class: bronchodilator ,adrenergic
Indication:bronchodilator used to prevent airway obstruction in asthma and
COPD Action: binds to Beta2 adrenergic receptors in the airway leading to
relaxation of the smooth muscles in the airways
Nursing Considerations:
- may decrease the effectiveness of Beta Blockers
-use caution with: heart disease, diabetes, glaucoma, seizure disorder
- overuse of inhalers can lead to bronchospasm
- monitor for chest pain and palpitations
- can decrease digoxin levels
Alendronate (Fosamax)
class: bone resorption inhibitor, biphosphnates
Indication: osteoporosis (aging, menopause, corticosteroid
induced) Action: inhibits osteoclast activity leading to inhibition of
resorption of bone Nursing Considerations:
- take first thing in the morning with full glass of water 30 min prior to eating
- assess serum calcium and vitamin D
- may lead to muscle pain
Alprazolam (Xanax)
class: benzodiazepine, anti-anxiety agent
Indication:anxiety, panic disorder, manage symptoms of PMS, insomnia,
mania, psychosis
Action: works in CNS to produce anxiolytic effect causing CNS depression.
Nursing Considerations:
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PM - may cause CNS depression, drowsiness,
Quizlet lethargy
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