OCN Certification Test | Questions and Answers |
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Terms in this set (270)
Most common cancers in men Prostate, lung, colon
Most common cancer in women Breast, lung colon
Clinical trials phase 1 establishes safe dose in very small group
Clinical trials phase 2 if drug has effect on certain cancer
Clinical trials phase 3 Is it better than existing drugs? Randomizes to
prove effectiveness
Which race is most likely to get White women
breast CA?
Breast CA risk factors Nulliparous, not breast feeding
When should breast CA screening Age 40
begin?
How often to screen for breast CA? 45-54 annually. >55 y.o. switch to every 2 years
, When is breast MRI indicated High risk individuals, esp. with family hx
Breast MRI starts at age 25 and mammogram starts
at 30
Adjuvant endocrine therapy Tamoxifen, aromatase, ovarian suppression
Tamoxifen Increases DVT risk, cataract formation, weight gain,
teratogen, endometrial CA, hot flashes, vaginal
discharge and dryness
Preferred in younger pts
Aromatase inhibitors (-zole) Sexual side effects, bone loss, bone density loss,
cardiovascular risk
HER2 Oncogene over expressed in aggressive breast
CAs
Triple (-) breast CA no expression of ER, PR, HER2
faster growing and aggressive, affects mainly
younger black/hispanic women, worse prognosis
HER+ breast cancer trastuzumab indicated
HER- breast cancer tamoxifen
majority of breast cancers occur in upper outer quadrant
epidermal growth factor is a protein, of which high levels associated with
more aggressive tumors, recurrence, poorer
prognosis and resistance to endocrine therapy
Common sites of breast CA mets Bone, lung, liver, brain
Verified Solutions | 2026 Edition | Pass
Guaranteed
Save
Terms in this set (270)
Most common cancers in men Prostate, lung, colon
Most common cancer in women Breast, lung colon
Clinical trials phase 1 establishes safe dose in very small group
Clinical trials phase 2 if drug has effect on certain cancer
Clinical trials phase 3 Is it better than existing drugs? Randomizes to
prove effectiveness
Which race is most likely to get White women
breast CA?
Breast CA risk factors Nulliparous, not breast feeding
When should breast CA screening Age 40
begin?
How often to screen for breast CA? 45-54 annually. >55 y.o. switch to every 2 years
, When is breast MRI indicated High risk individuals, esp. with family hx
Breast MRI starts at age 25 and mammogram starts
at 30
Adjuvant endocrine therapy Tamoxifen, aromatase, ovarian suppression
Tamoxifen Increases DVT risk, cataract formation, weight gain,
teratogen, endometrial CA, hot flashes, vaginal
discharge and dryness
Preferred in younger pts
Aromatase inhibitors (-zole) Sexual side effects, bone loss, bone density loss,
cardiovascular risk
HER2 Oncogene over expressed in aggressive breast
CAs
Triple (-) breast CA no expression of ER, PR, HER2
faster growing and aggressive, affects mainly
younger black/hispanic women, worse prognosis
HER+ breast cancer trastuzumab indicated
HER- breast cancer tamoxifen
majority of breast cancers occur in upper outer quadrant
epidermal growth factor is a protein, of which high levels associated with
more aggressive tumors, recurrence, poorer
prognosis and resistance to endocrine therapy
Common sites of breast CA mets Bone, lung, liver, brain
