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Advanced Pathophysiology Practice Questions – Immunity and Hematology – Comprehensive Practice Questions and Answers with Rationales

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This document contains advanced pathophysiology practice questions and answers focused on immunity and hematology. Topics include white blood cell disorders, lymphocyte function, leukemia, lymphoma, anemia, polycythemia, sickle cell disease, coagulation disorders, hematologic cancers, blood cell development, diagnostic laboratory values, and nursing management of hematologic conditions. The material presents exam-style multiple-choice questions with detailed rationales designed to strengthen understanding of pathophysiological mechanisms, diagnostic interpretation, and clinical nursing interventions. It serves as a comprehensive review resource for nursing, advanced practice nursing, and health sciences students preparing for examinations in pathophysiology and hematology.

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Institution
Advanced Pathophysiology 6501
Course
Advanced Pathophysiology 6501

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Advanced Pathophysiology Practice Questions / Immunity /
Hematology PRACTICE QUESTIONS AND ANSWERS LATEST
AND COMPREHENSIVE VERSION WITH VERIFIED
ANSWERS GUARANTEED PASS WITH INSTANT PDF
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Which cells are known as granular lymphocytes?



1. Kupffer cells

2. Microglial cells

3. T cells

4. Natural killer cells

4. Natural killer cells



1. Kupffer cells found in the liver are examples of macrophages. They are not known as granular
lymphocytes.

2. Microglial cells in the brain are examples of macrophages. They are not referred to as
granular lymphocytes.

3. T cells or T lymphocytes play a vital role in cell-mediated immunity. They are not known as
granular lymphocytes.

4. Natural killer cells act as a first-line of defense in the body and are a part of the innate
immune system. They contain cytoplasmic granules and are referred to as granular
lymphocytes.




Where does maturation of T lymphocytes occur?

,1. Spleen

2. Bone marrow

3. Thymus gland

4. Lymph nodes

3. Thymus gland



1. The maturation of B lymphocytes occurs in the spleen.

2. B lymphocytes mature in the bone marrow.

3. T lymphocytes mature in the thymus glands.

4. B cells, which are also known as B lymphocytes, mature in lymph nodes.




Which is the predominant immunoglobulin produced after a host's re-exposure to an antigen?



1. Immunoglobulin G (IgG)

2. Immunoglobulin A (IgA)

3. Immunoglobulin E (IgE)

4. Immunoglobulin D (IgD)

1. Immunoglobulin G (IgG)



1. Immunoglobulin G is the predominant immunoglobulin produced after a host's re-exposure
to an antigen. IgG comprises 75% to 80% of the total serum immunoglobulins.

2. Immunoglobulin A comprises 7% to 15% of the total serum immunoglobulins. IgA is mainly
found in saliva and nasal secretions.

3. Immunoglobulin E is generally present in a low concentration in the blood, but it increases
during allergic reactions.

4. Immunoglobulin D comprises only 1% of total serum immunoglobulins.

,A 27-year-old client is pregnant. The blood group of the client and the fetus are incompatible.
Which antibodies produced by the mother against the fetus's blood cells do not affect the
fetus?



1. IgM

2. IgG

3. IgD

4. none of the above

1. IgM



1. During pregnancy, if the mother and fetus have incompatible blood types, IgM antibodies will
be developed by the mother against the fetus's blood cells. However, because of the large size
of IgM antibodies, they cannot cross the placenta, and the fetus is protected.

2. During pregnancy, if the mother and fetus have incompatible blood types, IgM antibodies will
be developed by the mother against the fetus's blood cells. The mother will not produce IgG
antibodies in the given situation.

3. During pregnancy, if the mother and fetus have incompatible blood types, IgM antibodies will
be developed by the mother against the fetus's blood cells. The mother will not produce IgD
antibodies in the given situation.

4. The option "none of the above" is incorrect because IgM antibodies are developed by the
mother against the fetus's blood cells in the given condition.




Which immunity is developed by an individual after experiencing illness?

, 1. Innate immunity

2. Active acquired adaptive immunity

3. Passive acquired adaptive immunity

4. None of the above

2. Active acquired adaptive immunity



1. Innate immunity is the natural mechanism of the body that wards off foreign bodies as a first
line of defense. Mucous producing cells are part of the body's innate immunity mechanism.

2. Active acquired adaptive immunity is obtained through exposure to an antigen. It is
developed after an individual experiences an illness.

3. Passive acquired adaptive immunity is obtained by an individual after he or she is given pre-
made, fully formed antibodies, such as vaccines, against an antigen.

4. The option 'none of the above" is incorrect because the immunity developed by an individual
after he or she experiences an illness is active acquired adaptive immunity.



pg 204




Which is an example of passive acquired adaptive immunity?



1. Newborns receiving immunity through breast milk

2. Individuals becoming immune to chickenpox after infection

3. Individuals becoming immune to measles after infection

4. None of the above

1. Newborns receiving immunity through breast milk

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Institution
Advanced Pathophysiology 6501
Course
Advanced Pathophysiology 6501

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