NR566 Advanced Pharmacology for Care of the Family – Chamberlain University (Final Exam Weeks 5–8, 2025–2026) – Complete Guide with Verified Questions and Answers

NR566 Advanced Pharmacology for Care of
the Family – Chamberlain University (Final
Exam Weeks 5–8, 2025–2026) – Complete
Guide with Verified Questions and Answers

Question: 1 of 200
What are the common side effects of Donepezil?
Correct Answer: Gastrointestinal symptoms (nausea, vomiting, diarrhea),
hepatocholestatic symptoms, and peripheral neuropathy.


Question: 2 of 200
What precautions should be taken with Rivastigmine?
Correct Answer: Asthma or COPD, sick sinus syndrome, bradycardia, GI
bleeding, weight < 50 kg.


Question: 3 of 200
How is Rivastigmine (Exelon) administered?
Correct Answer: Orally or topically (transdermal patch).


Question: 4 of 200
What is the transdermal patch of Rivastigmine (Exelon) indicated for?
Correct Answer: Dementia associated with Parkinsonism.


Question: 5 of 200

,Will medications that induce or inhibit CYP450 affect Rivastigmine (Exelon)
metabolism?
Correct Answer: No, Rivastigmine is not metabolized by CYP450 enzymes.


Question: 6 of 200
What is the mechanism of action of Galantamine (Razadyne ER)?
Correct Answer: Elevates acetylcholine levels and modulates nicotinic
acetylcholine receptors.


Question: 7 of 200
What is the mechanism of action of Memantine (Namenda)?
Correct Answer: NMDA receptor antagonist that blocks glutamate-mediated
neurotoxicity.


Question: 8 of 200
Which medication is considered first-line treatment for moderate to severe
Alzheimer's disease?
Correct Answer: Memantine (Namenda).


Question: 9 of 200
What are the contraindications for Donepezil use?
Correct Answer: Hypersensitivity to Donepezil or piperidine derivatives.


Question: 10 of 200
What is the most serious adverse effect of cholinesterase inhibitors?
Correct Answer: Bradycardia and syncope due to vagotonic effects.

,Question: 11 of 200
Which anticholinesterase medication is associated with hepatotoxicity?
Correct Answer: Tacrine (no longer commonly used due to hepatotoxicity).


Question: 12 of 200
What is the recommended starting dose of Donepezil?
Correct Answer: 5 mg daily for mild to moderate Alzheimer's disease.


Question: 13 of 200
What is the maximum daily dose of Donepezil?
Correct Answer: 23 mg daily.


Question: 14 of 200
What is the mechanism of action of Levodopa in Parkinson's disease?
Correct Answer: Levodopa is a precursor to dopamine that crosses the blood-
brain barrier and is converted to dopamine in the brain.


Question: 15 of 200
Why is Carbidopa combined with Levodopa?
Correct Answer: Carbidopa inhibits peripheral decarboxylation of Levodopa,
increasing its availability to the brain and reducing peripheral side effects.


Question: 16 of 200
What is the most common side effect of Levodopa-Carbidopa?

, Correct Answer: Dyskinesia (involuntary movements).


Question: 17 of 200
Which vitamin can interfere with the effectiveness of Levodopa?
Correct Answer: Vitamin B6 (pyridoxine) can reduce the effectiveness of
Levodopa if taken without Carbidopa.


Question: 18 of 200
What are the adverse effects of dopamine agonists?
Correct Answer: Nausea, orthostatic hypotension, hallucinations, and impulse
control disorders.


Question: 19 of 200
Which dopamine agonist is associated with fibrotic reactions?
Correct Answer: Pergolide (withdrawn due to cardiac valvular fibrosis).


Question: 20 of 200
What is the mechanism of action of Selegiline?
Correct Answer: MAO-B inhibitor that prevents dopamine breakdown.


Question: 21 of 200
What dietary restriction is required with Selegiline?
Correct Answer: Tyramine-restricted diet (especially at higher doses >10
mg/day).