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Family Medicine Shelf Exam 2026 | 800+ Questions & Answers | USPSTF Guidelines, AAFP Review, Preventive Medicine, Pediatrics, Internal Medicine & NBME Shelf Exam

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This comprehensive Family Medicine Shelf Exam 2026 study guide contains more than 800 high-yield questions and answers integrating USPSTF preventive care recommendations, AAFP clinical guidelines, Blueprints Family Medicine concepts, and board-style review material commonly tested on Family Medicine Shelf, NBME Subject Examinations, USMLE Step 2 CK, Step 3, COMLEX, and Primary Care certification assessments. The resource provides a structured question-and-answer format designed to improve clinical reasoning, evidence-based decision-making, preventive care knowledge, and examination performance across the broad spectrum of Family Medicine. Major content areas include preventive medicine, health maintenance, cardiovascular disease prevention, hypertension management, lipid disorders, diabetes screening, women's health, obstetrics, gynecology, pediatrics, immunizations, infectious diseases, pulmonology, gastroenterology, nephrology, rheumatology, orthopedics, dermatology, ophthalmology, behavioral health, substance use disorders, geriatrics, emergency medicine, and musculoskeletal medicine. High-yield topics reviewed include abdominal aortic aneurysm screening, breast and cervical cancer screening, colorectal cancer prevention, osteoporosis management, sexually transmitted infections, hepatitis screening, HIV prevention, asthma and COPD treatment algorithms, common gastrointestinal disorders, migraine management, rheumatologic diseases, joint disorders, pneumonia treatment, dermatologic conditions, anemia evaluation, and evidence-based primary care interventions. The document places strong emphasis on USPSTF recommendations and preventive care guidelines that frequently appear on Shelf examinations and licensing assessments. Learners will review screening indications, diagnostic criteria, treatment pathways, risk factor assessment, vaccination schedules, counseling recommendations, and disease prevention strategies across all age groups. The material also includes practical clinical pearls for ambulatory medicine, outpatient management, chronic disease prevention, and longitudinal patient care. The content aligns with educational standards and clinical principles found in the United States Preventive Services Task Force (USPSTF) Recommendations, American Academy of Family Physicians (AAFP) Clinical Practice Guidelines, Blueprints Family Medicine, Current Medical Diagnosis & Treatment, Harrison’s Principles of Internal Medicine, Nelson Textbook of Pediatrics, Rakel Textbook of Family Medicine, and peer-reviewed literature published in American Family Physician, The Journal of the American Board of Family Medicine (JABFM), Annals of Family Medicine, JAMA, BMJ, Annals of Internal Medicine, and The New England Journal of Medicine (NEJM). These references form the foundation of modern evidence-based primary care and preventive medicine education. Relevant Students: Family Medicine Clerkship Students NBME Family Medicine Shelf Exam Candidates USMLE Step 2 CK Candidates USMLE Step 3 Candidates COMLEX Level 2 CE Candidates COMLEX Level 3 Candidates Medical Students Family Medicine Residents Internal Medicine Residents Primary Care Residents Physician Assistant Students Nurse Practitioner Students International Medical Graduates Preventive Medicine Trainees Primary Care Physicians Family Medicine Board Certification Candidates Healthcare Professionals Reviewing Clinical Guidelines Keywords: Family Medicine Shelf Exam, Family Medicine Shelf Review, NBME Family Medicine, USPSTF Guidelines, AAFP Questions, Preventive Medicine, Family Medicine Questions and Answers, Primary Care Review, USMLE Step 2 CK, USMLE Step 3, COMLEX Review, Internal Medicine Review, Pediatrics Review, Women's Health, Obstetrics and Gynecology, Cardiovascular Prevention, Hypertension Management, Diabetes Screening, Cancer Screening, Immunization Schedule, Infectious Diseases, Musculoskeletal Medicine, Rheumatology Review, Dermatology Review, Gastroenterology Review, Pulmonology Review, Nephrology Review, Evidence-Based Medicine, Clinical Guidelines, Board Examination Preparation

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Institution
Family Medicine
Course
Family medicine

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Family Medicine Shelf (USPSTF
+ Blueprints + AAFP Questions)
2026 Expert Verifed Ace the
Text



Screening for AAA - ANSWER ✔✔Men 65-75 who have ever smoked

(A)


Test used to screen for AAA - ANSWER ✔✔Abdominal duplex

ultrasonography

,Treatment for AAA - ANSWER ✔✔>5.5 cm --> surgery


3.0-5.4 cm --> repeated surveillance Q3-12 months

Growth >1.0 cm/yr --> surgery


Screening for Alcohol Misuse - ANSWER ✔✔Persons older than 18

years


Screening Tests for Alcohol Misuse - ANSWER ✔✔AUDIT, AUDIT-C,

or number of times person drank >5 (4 if woman or older than 65) drinks

in the past year


Treatment for Alcohol Misuse - ANSWER ✔✔Behavioral Counseling

interventions


Recommendation for Aspirin Usage - ANSWER ✔✔Men 45-79 years

old (MI protection)

Women 55-79 (Stroke protection)




*Benefit of MI reduction must outweigh the risk of GI hemorrhage


Risk Factors For GI Hemorrhage - ANSWER ✔✔Men


Other NSAID usage

Hx of GI ulcer

,Uncontrolled HTN

Anticoagulation


Screening for Asymptomatic Bacteriuria - ANSWER ✔✔Women at

12-16 weeks of pregnancy or first prenatal visit if farther along


Screening Test for Asymptomatic Bacteriuria - ANSWER ✔✔Urine

culture




Dipstick and microscopy have poor PPV and NPV


Treatment for Asymptomatic Bacteriuria - ANSWER ✔✔Nitrofurantoin


Prophylactic Aspirin for the Prevention of Colon Cancer - ANSWER

✔✔The USPSTF DOES NOT recommend this due to risk of GI

hemorrhage


Bacterial Vaginosis Screening in Pregnant Women - ANSWER

✔✔The USPSTF DOES NOT recommend this due to lack of evidence

that it reduces mortality or morbidity


Amsel Criteria - ANSWER ✔✔Need 3/4:


1. Fishy odor with addition of KOH

2. Vaginal pH >4.7

COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2026. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
3

, 3. Clue cells on wet mount

4. Thin, homogenous discharge


Treatment of BV - ANSWER ✔✔Oral Metronidazole or oral

Clindamycin

or

Vaginal Metronidazole or Vaginal Clindamycin creams


Screening for Bladder Cancer - ANSWER ✔✔The USPSTF DOES

NOT recommend this due to lack of accurate screening methods


Screening for HTN - ANSWER ✔✔Adults > 18 years


Diagnosis of HTN - ANSWER ✔✔>140 systolic or >90 diastolic


Must have 2 different BP readings that are elevated over a period of 1-

several weeks


Categories of BP - ANSWER ✔✔Normal = <120/<80


PreHTN = 120-129/80-89

Stage 1 HTN = 140-159/90-99

Stage 2 HTN = 160+/100+


Major CV Risk Factors - ANSWER ✔✔HTN

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