LATG Chapter 5. Health Surveillance &
Quality Assurance
Which of the following best describes the detection of adventitious bacteria, viruses, or
parasites at an early stage of infection in an animal facility?
a. Health surveillance
b. Quality assurance
c. Animal observation
d. Environmental monitoring - answera
What is the term for animals used in the health surveillance of rodent colonies?
a. Standards
b. Sentinels
c. Controls
d. Samples - answerb
What is the goal of a quality assurance program?
a. To ensure that all experimental animals have the best health surveillance possible
b. To ensure that a program meets specified requirements
c. To ensure that all experimentation is done in accordance with scientific standards
d. To ensure that all experimental results are published in scientific journals - answerb
What is the main goal of maintaining sentinels in animal rooms?
a. To identify the pathogens present in newly received animals
b. To protect the colonies from infection
c. To allow early detection of infection affecting the colony
d. To provide animals that can be used as alternates in case of death of experimental
animals - answerc
The health surveillance program is a component of the quality assurance program.
a. True
b. False - answera
An animal supplier's health status report is an assurance that the animals arriving in the
facility are healthy and free of pathogens.
a. True
b. False - answerb
What route is the highest risk for introducing pathogens into an animal facility?
a. Introduction of live animals
b. Contamination brought in by facility staff
c. Growth of microorganisms in the room's waste containers
, d. Spoilage of feed and bedding - answera
Which organism is identified by a cecal exam postmortem?
a. Helicobacter spp.
b. Brucella spp.
c. Syphacia spp.
d. Aspiculuris spp. - answerd
How many days does it generally take for an animal to develop an immmune response
to an agent?
a. 3-5
b. 10-14
c. 15-20
d. 30 or more - answerb
Which time frame of the animal's health status is revealed by serological tests on
samples taken when animals arrive at the facility?
a. Health status upon arrival at the facility
b. Health status when they left the vendor's facility
c. Health status 2 weeks before shipment
d. Health status 4-6 weeks prior to arrival at the facility - answerc
If an animals tests negative for a pathogen 3 weeks after arrival at the facility, which of
the following conclusions is appropriate?
a. The animal was free of this pathogen 2 weeks after arrival.
b. The animal was free of the pathogen when shipped.
c. The animal is free of the pathogen at the present time.
d. All of the above - answerb
The best time to monitor for microbial antibodies is when the animals are nursing.
a. True
b. False - answerb
What is a common method used to detect exposure to viral pathogens?
a. Microbial colony counts
b. Gel electrophoresis
c. ELISA
d. All of the above - answerc
What does the acronym ELISA stand for?
a. Enzyme-linked immunosorbent assay
b. Enzyme-labile immunosorbent assay
c. Enhanced lipemic immunosorbent assay
d. Endocrine laboratory immunosorbent assay - answera
What does the acronym MFI stand for?
Quality Assurance
Which of the following best describes the detection of adventitious bacteria, viruses, or
parasites at an early stage of infection in an animal facility?
a. Health surveillance
b. Quality assurance
c. Animal observation
d. Environmental monitoring - answera
What is the term for animals used in the health surveillance of rodent colonies?
a. Standards
b. Sentinels
c. Controls
d. Samples - answerb
What is the goal of a quality assurance program?
a. To ensure that all experimental animals have the best health surveillance possible
b. To ensure that a program meets specified requirements
c. To ensure that all experimentation is done in accordance with scientific standards
d. To ensure that all experimental results are published in scientific journals - answerb
What is the main goal of maintaining sentinels in animal rooms?
a. To identify the pathogens present in newly received animals
b. To protect the colonies from infection
c. To allow early detection of infection affecting the colony
d. To provide animals that can be used as alternates in case of death of experimental
animals - answerc
The health surveillance program is a component of the quality assurance program.
a. True
b. False - answera
An animal supplier's health status report is an assurance that the animals arriving in the
facility are healthy and free of pathogens.
a. True
b. False - answerb
What route is the highest risk for introducing pathogens into an animal facility?
a. Introduction of live animals
b. Contamination brought in by facility staff
c. Growth of microorganisms in the room's waste containers
, d. Spoilage of feed and bedding - answera
Which organism is identified by a cecal exam postmortem?
a. Helicobacter spp.
b. Brucella spp.
c. Syphacia spp.
d. Aspiculuris spp. - answerd
How many days does it generally take for an animal to develop an immmune response
to an agent?
a. 3-5
b. 10-14
c. 15-20
d. 30 or more - answerb
Which time frame of the animal's health status is revealed by serological tests on
samples taken when animals arrive at the facility?
a. Health status upon arrival at the facility
b. Health status when they left the vendor's facility
c. Health status 2 weeks before shipment
d. Health status 4-6 weeks prior to arrival at the facility - answerc
If an animals tests negative for a pathogen 3 weeks after arrival at the facility, which of
the following conclusions is appropriate?
a. The animal was free of this pathogen 2 weeks after arrival.
b. The animal was free of the pathogen when shipped.
c. The animal is free of the pathogen at the present time.
d. All of the above - answerb
The best time to monitor for microbial antibodies is when the animals are nursing.
a. True
b. False - answerb
What is a common method used to detect exposure to viral pathogens?
a. Microbial colony counts
b. Gel electrophoresis
c. ELISA
d. All of the above - answerc
What does the acronym ELISA stand for?
a. Enzyme-linked immunosorbent assay
b. Enzyme-labile immunosorbent assay
c. Enhanced lipemic immunosorbent assay
d. Endocrine laboratory immunosorbent assay - answera
What does the acronym MFI stand for?
