LATg Chapter 6
Which of the following best describes the detection of bacteria, viruses, or parasites at
an early stage of infection in an animal facility?
a. Health surveillance
b. Quality assurance
c. Animal observation
d. Environmental monitoring - answerA
What is the term for animals used in the health surveillance of rodent colonies?
a. Standards
b. Sentinels
c. Controls
d. Samples - answerB
What is the goal of a quality assurance program?
a. To ensure that all experimental animals have the best health surveillance possible
b. To ensure that a program meets specified requirements
c. To ensure that all experimentation is done in accordance with scientific standards
d. To ensure that all experimental results are published in scientific journals - answerB
What is the main goal of maintaining sentinels in animal rooms?
a. To identify the pathogens present in newly received animals
b. To protect the colonies from infection
c. To allow early detection of infection affecting the colony
d. To provide animals that can be used as alternates in case of death of experimental
animals - answerC
Which of the following poses the highest risk for introducing pathogens into an animal
facility?
a. Introduction of live animals
b. Contamination brought in by facility staff
c. Growth of microorganisms in the room's waste containers
d. Spoilage of feed and bedding - answerA
Which organism is identified by a cecal exam postmortem?
a. Helicobacter spp.
b. Brucella spp.
c. Syphacia spp.
d. Aspiculuris spp. - answerD
How many days does it generally take for an animal to develop an immune response to
an agent? a. 3-5
b. 10-14
, c. 15-20
d. 30 or more - answer7.
Which time frame of the animal's health status is revealed by serological tests on
samples taken when animals arrive at the facility?
a. Health status upon arrival at the facility
b. Health status when they left the vendor's facility
c. Health status 2 weeks before shipment
d. Health status 4-6 weeks prior to arrival at the facility - answerC
If an animals tests negative for a pathogen 3 weeks after arrival at the facility, which of
the following conclusions is appropriate?
a. The animal was free of this pathogen 2 weeks after arrival.
b. The animal was free of the pathogen when shipped.
c. The animal is free of the pathogen at the present time.
d. The animal was free of the pathogen 2 weeks prior to shipment. - answerB
What is the minimum age for sentinel animals?
a. 3 weeks old
b. 4-8 weeks old
c. 8-12 weeks old
d. 6 months old - answerC
What is a main factor for determining the number animals used as sentinels?
a. The space available in the animal room
b. The cost involved in maintaining the animals
c. The number of pathogens being tested
d. The expected morbidity of the agents being monitored - answerD
When microisolation cages are being used to house experimental animals, the sentinels
are housed in cages that contain from other cages in the room.
a. mixed bedding
b. used water bottles
c. neonates
d. soiled enrichment devices - answerA
Why is it recommended that sentinel cages be moved frequently around the room?
a. To ensure that the sentinels are unaffected by variations in air flow or humidity
b. To allow airborne transmission to be sampled from different areas of the room
c. To avoid spreading disease by long-term exposure to sick animals
d. To ensure that the sentinels are in contact with all animals in the room - answerB
How soon after exposure should a sentinel be tested for a specific pathogen?
a. Immediately
b. Within 2 weeks after exposure
c. 3 to 6 weeks after exposure
Which of the following best describes the detection of bacteria, viruses, or parasites at
an early stage of infection in an animal facility?
a. Health surveillance
b. Quality assurance
c. Animal observation
d. Environmental monitoring - answerA
What is the term for animals used in the health surveillance of rodent colonies?
a. Standards
b. Sentinels
c. Controls
d. Samples - answerB
What is the goal of a quality assurance program?
a. To ensure that all experimental animals have the best health surveillance possible
b. To ensure that a program meets specified requirements
c. To ensure that all experimentation is done in accordance with scientific standards
d. To ensure that all experimental results are published in scientific journals - answerB
What is the main goal of maintaining sentinels in animal rooms?
a. To identify the pathogens present in newly received animals
b. To protect the colonies from infection
c. To allow early detection of infection affecting the colony
d. To provide animals that can be used as alternates in case of death of experimental
animals - answerC
Which of the following poses the highest risk for introducing pathogens into an animal
facility?
a. Introduction of live animals
b. Contamination brought in by facility staff
c. Growth of microorganisms in the room's waste containers
d. Spoilage of feed and bedding - answerA
Which organism is identified by a cecal exam postmortem?
a. Helicobacter spp.
b. Brucella spp.
c. Syphacia spp.
d. Aspiculuris spp. - answerD
How many days does it generally take for an animal to develop an immune response to
an agent? a. 3-5
b. 10-14
, c. 15-20
d. 30 or more - answer7.
Which time frame of the animal's health status is revealed by serological tests on
samples taken when animals arrive at the facility?
a. Health status upon arrival at the facility
b. Health status when they left the vendor's facility
c. Health status 2 weeks before shipment
d. Health status 4-6 weeks prior to arrival at the facility - answerC
If an animals tests negative for a pathogen 3 weeks after arrival at the facility, which of
the following conclusions is appropriate?
a. The animal was free of this pathogen 2 weeks after arrival.
b. The animal was free of the pathogen when shipped.
c. The animal is free of the pathogen at the present time.
d. The animal was free of the pathogen 2 weeks prior to shipment. - answerB
What is the minimum age for sentinel animals?
a. 3 weeks old
b. 4-8 weeks old
c. 8-12 weeks old
d. 6 months old - answerC
What is a main factor for determining the number animals used as sentinels?
a. The space available in the animal room
b. The cost involved in maintaining the animals
c. The number of pathogens being tested
d. The expected morbidity of the agents being monitored - answerD
When microisolation cages are being used to house experimental animals, the sentinels
are housed in cages that contain from other cages in the room.
a. mixed bedding
b. used water bottles
c. neonates
d. soiled enrichment devices - answerA
Why is it recommended that sentinel cages be moved frequently around the room?
a. To ensure that the sentinels are unaffected by variations in air flow or humidity
b. To allow airborne transmission to be sampled from different areas of the room
c. To avoid spreading disease by long-term exposure to sick animals
d. To ensure that the sentinels are in contact with all animals in the room - answerB
How soon after exposure should a sentinel be tested for a specific pathogen?
a. Immediately
b. Within 2 weeks after exposure
c. 3 to 6 weeks after exposure
