NR 293 EXAM 1 QUESTIONS & ANSWERS
100% CORRECT (FULLY SOLVED)
____________ determines the rate of drug dissolution -
correct answer- Dosage form
Absorption - correct answer- Movement of a
drug from its site of administration into the blood stream
for distribution to the tissues
Absorption in Neonate and Pediatric patient - correct
answer- -Gastric pH is less acidic (acid producing
cells in stomach are immature until 1-2 years of age)
-Gastric emptying is slowed (slow/irregular peristalsis)
-First-pass elimination by the liver is reduced (immaturity
of the liver and reduced levels of microsomal enzymes)
-Intramuscular absorption is faster and irregular
Actions of antibiotics - correct answer-
Bactericidal: kill bacteria
,Bacteriostatic: inhibit growth of susceptible bacteria,
rather than killing them immediately - will eventually lead
to bacterial death
Acute therapy - correct answer- Involves more
intensive drug treatment
-Implemented in acutely ill or cricially ill
-Often needed to sustain life or treat disease
Ex: vasopressors for BP, volume expanders for shock, and
intensive chemo for pt with new cancer dx
Additive effects - correct answer- Two drugs
with similar actions are given together
-Often used so smaller doses of each drug can be given
1+1=2
Adverse drug event - correct answer- Any
undesirable occurrence involving medication
,Adverse drug reaction - correct answer- Any
reaction to a drug that is unexpected and undesirable
-Occurs at therapeutic drug dosages
-May or may not be caused by medication errors
-Specific to particular drug groups
Adverse effects - correct answer- Unintended
adverse drug reactions
Adverse effects of Sulfonamides: Blood - correct
answer- -Anemia
-Agranulocytosis
-Hemolytic and aplastic thrombocytopenia
Adverse effects of Sulfonamides: GI - correct
answer- -Nausea
-vomiting
-diarrhea
-pancreatitis
, Adverse effects of Sulfonamides: Integumentary -
correct answer- -Photosensitivity
-Exexfoliative dermatitis
-Stevens-Johnson syndrom
-Epidermal necrolysis
Adverse effects of Sulfonamides: Other - correct
answer- -Hepatotoxicity
-convulsions
-crystalluria
-toxic nephrosis
-headache
-peripheral neuritis
-urticaria
-cough
Affinity - correct answer- Degree to which a
drug attaches to and binds with a receptor
Strongest affinity = greatest response
100% CORRECT (FULLY SOLVED)
____________ determines the rate of drug dissolution -
correct answer- Dosage form
Absorption - correct answer- Movement of a
drug from its site of administration into the blood stream
for distribution to the tissues
Absorption in Neonate and Pediatric patient - correct
answer- -Gastric pH is less acidic (acid producing
cells in stomach are immature until 1-2 years of age)
-Gastric emptying is slowed (slow/irregular peristalsis)
-First-pass elimination by the liver is reduced (immaturity
of the liver and reduced levels of microsomal enzymes)
-Intramuscular absorption is faster and irregular
Actions of antibiotics - correct answer-
Bactericidal: kill bacteria
,Bacteriostatic: inhibit growth of susceptible bacteria,
rather than killing them immediately - will eventually lead
to bacterial death
Acute therapy - correct answer- Involves more
intensive drug treatment
-Implemented in acutely ill or cricially ill
-Often needed to sustain life or treat disease
Ex: vasopressors for BP, volume expanders for shock, and
intensive chemo for pt with new cancer dx
Additive effects - correct answer- Two drugs
with similar actions are given together
-Often used so smaller doses of each drug can be given
1+1=2
Adverse drug event - correct answer- Any
undesirable occurrence involving medication
,Adverse drug reaction - correct answer- Any
reaction to a drug that is unexpected and undesirable
-Occurs at therapeutic drug dosages
-May or may not be caused by medication errors
-Specific to particular drug groups
Adverse effects - correct answer- Unintended
adverse drug reactions
Adverse effects of Sulfonamides: Blood - correct
answer- -Anemia
-Agranulocytosis
-Hemolytic and aplastic thrombocytopenia
Adverse effects of Sulfonamides: GI - correct
answer- -Nausea
-vomiting
-diarrhea
-pancreatitis
, Adverse effects of Sulfonamides: Integumentary -
correct answer- -Photosensitivity
-Exexfoliative dermatitis
-Stevens-Johnson syndrom
-Epidermal necrolysis
Adverse effects of Sulfonamides: Other - correct
answer- -Hepatotoxicity
-convulsions
-crystalluria
-toxic nephrosis
-headache
-peripheral neuritis
-urticaria
-cough
Affinity - correct answer- Degree to which a
drug attaches to and binds with a receptor
Strongest affinity = greatest response
