Latest 2025-2026 GI and Neurological
Nursing ATI Exam Prep: Comprehensive
Practice Questions and Answers to
Ensure First-Attempt Success and Avoid
Resits
| **Medication Class** | **Examples** | **Key Nursing & Patient Education** |
| :--- | :--- | :--- |
| **PPIs** | Omeprazole, Pantoprazole | * **Administration:** Do not crush/chew sustained-release
capsules.<br>* **Monitoring:** Risk for pneumonia (elderly/COPD), monitor Digoxin levels
carefully.<br>* **Timing:** Active ulcers need 4-8 weeks to heal. |
| **H2 Receptor Antagonists** | Famotidine (Pepcid) | * **Interaction:** Antacids reduce
absorption—stagger doses.<br>* **Cimetidine caution:** Androgen issues & CNS effects in elderly. |
, | **Mucosal Protectant** | Sucralfate | * **Key Fact:** Forms a protective layer for 6 hours. No
systemic effects.<br>* **Administration:** Give 1 hour **before** meals and at bedtime. |
| **Prostaglandin Analog** | Misoprostol | * **Use:** Prevents NSAID-induced ulcers.<br>*
**Contraindication:** **Pregnancy Risk X** (causes uterine contractions/abortion). |
| **Osmotic Laxative** | Magnesium Hydroxide (Milk of Magnesia) | * **Risk:** Can cause
**hypermagnesemia** in renal failure (avoid use). |
| **Antiemetic** | Ondansetron (Zofran) | * **SE:** Headache, dizziness, constipation.<br>*
**Interaction:** Monitor for serotonin syndrome if on SSRIs. |
**GI Disorders Practice Questions (ATI-Style)**
Try these questions based on the 2025/2026 test bank rationales:
1. **Scenario:** A client with chronic pancreatitis is being discharged. Which statement by the client
indicates a need for further teaching?
- A) "I will increase my daily protein intake."
- B) "I will decrease my caloric intake when I have abdominal pain."
- C) "I will avoid alcohol."
- D) "I will take pancreatic enzymes with meals."
> **Answer:** B is incorrect (needs teaching). Malnutrition is a major risk; patients need *increased*
calories to maintain weight, even with pain present .
2. **Scenario:** A nurse is caring for a client receiving Total Parenteral Nutrition (TPN). The next
container is delayed by 2 hours. Which fluid should the nurse infuse to prevent hypoglycemia?
- A) Dextrose 5% in water
- B) Dextrose 10% in water
- C) 0.9% Sodium Chloride
- D) Lactated Ringer's
Nursing ATI Exam Prep: Comprehensive
Practice Questions and Answers to
Ensure First-Attempt Success and Avoid
Resits
| **Medication Class** | **Examples** | **Key Nursing & Patient Education** |
| :--- | :--- | :--- |
| **PPIs** | Omeprazole, Pantoprazole | * **Administration:** Do not crush/chew sustained-release
capsules.<br>* **Monitoring:** Risk for pneumonia (elderly/COPD), monitor Digoxin levels
carefully.<br>* **Timing:** Active ulcers need 4-8 weeks to heal. |
| **H2 Receptor Antagonists** | Famotidine (Pepcid) | * **Interaction:** Antacids reduce
absorption—stagger doses.<br>* **Cimetidine caution:** Androgen issues & CNS effects in elderly. |
, | **Mucosal Protectant** | Sucralfate | * **Key Fact:** Forms a protective layer for 6 hours. No
systemic effects.<br>* **Administration:** Give 1 hour **before** meals and at bedtime. |
| **Prostaglandin Analog** | Misoprostol | * **Use:** Prevents NSAID-induced ulcers.<br>*
**Contraindication:** **Pregnancy Risk X** (causes uterine contractions/abortion). |
| **Osmotic Laxative** | Magnesium Hydroxide (Milk of Magnesia) | * **Risk:** Can cause
**hypermagnesemia** in renal failure (avoid use). |
| **Antiemetic** | Ondansetron (Zofran) | * **SE:** Headache, dizziness, constipation.<br>*
**Interaction:** Monitor for serotonin syndrome if on SSRIs. |
**GI Disorders Practice Questions (ATI-Style)**
Try these questions based on the 2025/2026 test bank rationales:
1. **Scenario:** A client with chronic pancreatitis is being discharged. Which statement by the client
indicates a need for further teaching?
- A) "I will increase my daily protein intake."
- B) "I will decrease my caloric intake when I have abdominal pain."
- C) "I will avoid alcohol."
- D) "I will take pancreatic enzymes with meals."
> **Answer:** B is incorrect (needs teaching). Malnutrition is a major risk; patients need *increased*
calories to maintain weight, even with pain present .
2. **Scenario:** A nurse is caring for a client receiving Total Parenteral Nutrition (TPN). The next
container is delayed by 2 hours. Which fluid should the nurse infuse to prevent hypoglycemia?
- A) Dextrose 5% in water
- B) Dextrose 10% in water
- C) 0.9% Sodium Chloride
- D) Lactated Ringer's
