ATI RN FUNDAMENTALS PROCTORED EXAM STUDY
GUIDE | ACTUAL 150+ PRACTICE
QUESTIONS AND CORRECT ANSWERS ALREADY GRADED
A+ |GUARANTEED PASS
Ace your ATI RN Fundamentals Proctored Exam with this ultimate 2026 study
guide! Packed with highly predictive practice questions, verified answers, and
deep clinical Rationales. Master safety, infection control, isolation precautions,
and ADPIE prioritization. Includes Next-Generation NCLEX (NGN) style case
scenarios to secure your Level 2 or 3 score. Stop stressing and start studying the
exact concepts tested on the official ATI exam. Download instantly for a
guaranteed pass!
,Question 1
A nurse is caring for a client who has a prescription for protective environment precautions.
Which of the following interventions should the nurse implement?
• A. Place the client in a room with negative-pressure airflow.
• B. Ensure the client's room has a positive-pressure airflow system.
• C. Wear an N95 respirator when providing direct client care.
• D. Keep the client's room door open at all times.
Rationale: Protective environments (often used for highly immunocompromised clients like
stem-cell transplant recipients) require a private room with positive-pressure airflow. This
prevents outside air from flowing into the room when the door is opened. Negative pressure is
used for airborne infection isolation.
Question 2
A nurse is reviewing isolation precautions with a newly licensed nurse. The nurse should explain
that which of the following clients requires airborne precautions?
• A. A client who has pertussis.
• B. A client who has seasonal influenza.
• C. A client who has active pulmonary tuberculosis.
• D. A client who has a large pressure injury infected with MRSA.
Rationale: Pulmonary tuberculosis (TB), measles, and varicella (chickenpox) require airborne
precautions, including a negative-pressure room and an N95 mask. Pertussis and influenza
require droplet precautions, while MRSA skin infections require contact precautions. [1, 2, 3]
Question 3
A nurse is preparing to enter the room of a client who is on airborne precautions to perform a
routine physical assessment. Which of the following personal protective equipment (PPE) is
mandatory for the nurse to don?
, • A. An N95 respirator.
• B. A surgical mask.
• C. A face shield.
• D. Sterile gloves.
Rationale: An N95 particulate respirator or a powered air-purifying respirator (PAPR) is
strictly required before entering an airborne isolation room to filter out tiny airborne droplets.
A standard surgical mask does not provide adequate filtration for airborne pathogens. [1, 2]
Question 4
A nurse must transport a client who is on airborne precautions to the radiology department for
a chest X-ray. Which of the following actions should the nurse take?
• A. Request that the radiology technician perform a portable X-ray in the hallway.
• B. Have the client wear an N95 respirator during transport.
• C. Place a standard surgical mask on the client during transport.
• D. Notify the transport team that no mask is needed if the hallway is clear.
Rationale: When a client on airborne precautions leaves their negative-pressure room, they
must wear a standard surgical mask to contain respiratory secretions. They do not wear an
N95 respirator because the exhalation valves or tight fit can increase breathing effort
unnecessarily for a sick client. [1]
Question 5
A nurse is removing personal protective equipment (PPE) after caring for a client in airborne
isolation. According to standard guidelines, which item of PPE should the nurse remove last?
• A. Gloves.
• B. Goggles.
• C. Gown.
• D. Respirator mask.
, Rationale: The respirator or mask is always removed last, after leaving the client's room and
closing the door. This protects the nurse from inhaling any lingering airborne particles still
suspended in the isolation room's air.
Question 6
A nurse is caring for a client who has a prescription for contact precautions. Which of the
following actions should the nurse take?
• A. Wear an N95 respirator when entering the client's room.
• B. Dedicate a stethoscope and blood pressure cuff for exclusive use with this client.
• C. Ensure the client's room has a negative-pressure airflow system.
• D. Keep the client's room door closed at all times.
Rationale: Contact precautions require dedicating noncritical client-care equipment, such as a
stethoscope or thermometer, to that specific client to prevent cross-contamination to other
clients. Gowns and gloves are standard, but a special airflow room or N95 mask is not needed.
Question 7
A nurse is preparing to perform hand hygiene after providing care to a client who has a
Clostridioides difficile (C. diff) infection. Which of the following methods should the nurse use?
• A. Apply an alcohol-based hand rub and rub until dry.
• B. Wash hands thoroughly with antimicrobial soap and water.
• C. Rinse hands with hot tap water without using soap.
• D. Wipe hands clean using a chlorhexidine-impregnated wipe.
Rationale: Alcohol does not kill C. diff spores. The physical friction of washing hands with soap
and rinsing under running water is required to mechanically remove the spores from the skin.
Question 8
A nurse is preparing to irrigate a large wound that is heavily infected with methicillin-resistant
Staphylococcus aureus (MRSA). Which of the following personal protective equipment (PPE)
combinations should the nurse don?
GUIDE | ACTUAL 150+ PRACTICE
QUESTIONS AND CORRECT ANSWERS ALREADY GRADED
A+ |GUARANTEED PASS
Ace your ATI RN Fundamentals Proctored Exam with this ultimate 2026 study
guide! Packed with highly predictive practice questions, verified answers, and
deep clinical Rationales. Master safety, infection control, isolation precautions,
and ADPIE prioritization. Includes Next-Generation NCLEX (NGN) style case
scenarios to secure your Level 2 or 3 score. Stop stressing and start studying the
exact concepts tested on the official ATI exam. Download instantly for a
guaranteed pass!
,Question 1
A nurse is caring for a client who has a prescription for protective environment precautions.
Which of the following interventions should the nurse implement?
• A. Place the client in a room with negative-pressure airflow.
• B. Ensure the client's room has a positive-pressure airflow system.
• C. Wear an N95 respirator when providing direct client care.
• D. Keep the client's room door open at all times.
Rationale: Protective environments (often used for highly immunocompromised clients like
stem-cell transplant recipients) require a private room with positive-pressure airflow. This
prevents outside air from flowing into the room when the door is opened. Negative pressure is
used for airborne infection isolation.
Question 2
A nurse is reviewing isolation precautions with a newly licensed nurse. The nurse should explain
that which of the following clients requires airborne precautions?
• A. A client who has pertussis.
• B. A client who has seasonal influenza.
• C. A client who has active pulmonary tuberculosis.
• D. A client who has a large pressure injury infected with MRSA.
Rationale: Pulmonary tuberculosis (TB), measles, and varicella (chickenpox) require airborne
precautions, including a negative-pressure room and an N95 mask. Pertussis and influenza
require droplet precautions, while MRSA skin infections require contact precautions. [1, 2, 3]
Question 3
A nurse is preparing to enter the room of a client who is on airborne precautions to perform a
routine physical assessment. Which of the following personal protective equipment (PPE) is
mandatory for the nurse to don?
, • A. An N95 respirator.
• B. A surgical mask.
• C. A face shield.
• D. Sterile gloves.
Rationale: An N95 particulate respirator or a powered air-purifying respirator (PAPR) is
strictly required before entering an airborne isolation room to filter out tiny airborne droplets.
A standard surgical mask does not provide adequate filtration for airborne pathogens. [1, 2]
Question 4
A nurse must transport a client who is on airborne precautions to the radiology department for
a chest X-ray. Which of the following actions should the nurse take?
• A. Request that the radiology technician perform a portable X-ray in the hallway.
• B. Have the client wear an N95 respirator during transport.
• C. Place a standard surgical mask on the client during transport.
• D. Notify the transport team that no mask is needed if the hallway is clear.
Rationale: When a client on airborne precautions leaves their negative-pressure room, they
must wear a standard surgical mask to contain respiratory secretions. They do not wear an
N95 respirator because the exhalation valves or tight fit can increase breathing effort
unnecessarily for a sick client. [1]
Question 5
A nurse is removing personal protective equipment (PPE) after caring for a client in airborne
isolation. According to standard guidelines, which item of PPE should the nurse remove last?
• A. Gloves.
• B. Goggles.
• C. Gown.
• D. Respirator mask.
, Rationale: The respirator or mask is always removed last, after leaving the client's room and
closing the door. This protects the nurse from inhaling any lingering airborne particles still
suspended in the isolation room's air.
Question 6
A nurse is caring for a client who has a prescription for contact precautions. Which of the
following actions should the nurse take?
• A. Wear an N95 respirator when entering the client's room.
• B. Dedicate a stethoscope and blood pressure cuff for exclusive use with this client.
• C. Ensure the client's room has a negative-pressure airflow system.
• D. Keep the client's room door closed at all times.
Rationale: Contact precautions require dedicating noncritical client-care equipment, such as a
stethoscope or thermometer, to that specific client to prevent cross-contamination to other
clients. Gowns and gloves are standard, but a special airflow room or N95 mask is not needed.
Question 7
A nurse is preparing to perform hand hygiene after providing care to a client who has a
Clostridioides difficile (C. diff) infection. Which of the following methods should the nurse use?
• A. Apply an alcohol-based hand rub and rub until dry.
• B. Wash hands thoroughly with antimicrobial soap and water.
• C. Rinse hands with hot tap water without using soap.
• D. Wipe hands clean using a chlorhexidine-impregnated wipe.
Rationale: Alcohol does not kill C. diff spores. The physical friction of washing hands with soap
and rinsing under running water is required to mechanically remove the spores from the skin.
Question 8
A nurse is preparing to irrigate a large wound that is heavily infected with methicillin-resistant
Staphylococcus aureus (MRSA). Which of the following personal protective equipment (PPE)
combinations should the nurse don?
