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Human Blood and Circulation Complete Notes.

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Introduction to Human Blood, Generel Composition of Blood and Major Functions of Human Blood.

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Title: Human Blood Notes pdf
1. Introduction to Human Blood
Blood is a specialized, red-colored fluid connective tissue that circulates through the
cardiovascular system of humans and other animals. It is slightly alkaline in nature, with a
standard pH of around 7.4. Blood tastes salty and feels sticky. In an adult human body, there
is about 5 to 6 liters of blood, which accounts for approximately 8% of the total body weight.

2. General Composition of Blood
If we separate blood using a centrifuge machine, we can clearly see that blood is composed of
two main components:

 Blood Plasma (Liquid portion): Makes up about 55% of the total blood volume.
 Blood Cells or Corpuscles (Solid portion): Makes up about 45% of the total blood
volume.

A. Blood Plasma

Plasma is the straw-colored (faint yellow), liquid matrix of the blood. It is responsible for
carrying water, nutrients, and waste products throughout the body.

 Composition of Plasma:
o Water: About 90% to 92% of plasma is pure water.
o Solids: The remaining 8% to 10% contains organic and inorganic substances.
 Organic Substances: These include plasma proteins (Albumin, Globulin,
Fibrinogen), glucose, amino acids, lipids, hormones, and metabolic wastes (urea, uric
acid).
 Inorganic Substances: These include essential minerals and ions like Sodium,
Potassium , Calcium , Chloride and Bicarbonate .

B. Blood Cells or Corpuscles

Blood cells are suspended within the plasma. There are three major types of blood cells, each
serving a unique and vital function in the human body:

1. Red Blood Cells (RBC) or Erythrocytes

 Shape and Structure: These cells are biconcave and disc-shaped. In mature human
RBCs, there is no nucleus.
 Function: They contain a red, iron-rich protein called Hemoglobin. Hemoglobin
binds with oxygen to form oxyhemoglobin, which transports oxygen ($O_2$) from
the lungs to all body tissues.

2. White Blood Cells (WBC) or Leukocytes

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