University (WCU) – Quiz 1, 2, 3 Mastery Exam Bank |
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QUIZ 1 – Chapters 1, 2, 4, 7: Foundations of Pathophysiology, Cellular
Adaptation, and Neoplasia
Question 1
When the cause of a disease is due to unintended or unwanted medical treatment, the
term to describe this is:
A. Idiopathic
B. Iatrogenic
C. Genotype
D. Ecogenetics
Correct Answer: B
Rationale: Iatrogenic means that the cause was medical intervention. Idiopathic is
when the cause is unknown, genotype refers to genetic inheritance, and ecogenetics
involves the interaction between genetic makeup and environment.
Question 2
The study of specific characteristics and functions of a living organism and its parts is
called:
A. Pathology
B. Physiology
C. Etiology
D. Histology
Correct Answer: B
Rationale: Physiology is the study of the normal functioning of a living organism and
its parts. Pathology studies disease, etiology studies causes, and histology studies
tissues.
Question 3
A patient diagnosed with cancer presents with Cushing syndrome secondary to excessive
adrenocorticotropic hormone secretion. This syndrome is described as:
A. Paraneoplastic syndrome
B. Grading syndrome
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,C. Metastatic syndrome
D. Anaplastic syndrome
Correct Answer: A
Rationale: Paraneoplastic syndromes are systemic manifestations of cancer caused by
tumor products (like hormones) or immune responses, not directly by tumor invasion.
Question 4
Which term is used to describe the histologic characterization of tumor cells?
A. Staging
B. Grading
C. Metastasis
D. Anaplasia
Correct Answer: B
Rationale: Grading is the histologic characterization of tumor cells based on
differentiation and anaplasia. Staging describes the extent and spread of the tumor.
Question 5
Which type of cellular adaptation is most likely to occur as the result of chronic ischemia
to a region?
A. Hypertrophy
B. Hyperplasia
C. Atrophy
D. Metaplasia
Correct Answer: C
Rationale: Atrophy is a decrease in cell size due to decreased workload or chronic
ischemia. Hypertrophy is an increase in cell size, hyperplasia is an increase in cell
number, and metaplasia is a change in cell type.
Question 6
Apoptosis is a process that results in cellular:
A. Proliferation
B. Death
C. Hypertrophy
D. Metaplasia
Correct Answer: B
Rationale: Apoptosis is programmed cell death that is essential for maintaining
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, homeostasis and eliminating damaged or unnecessary cells without causing
inflammation.
Question 7
The increase in a normal adaptive response to the decreased availability of oxygen at
high altitudes is referred to as:
A. Acclimatization
B. Homeostasis
C. Allostasis
D. Adaptation
Correct Answer: A
Rationale: Acclimatization is the process by which the body adapts to environmental
changes, such as increased erythropoiesis in response to high-altitude hypoxia.
Question 8
An increase in which of these characteristics would be present in cells that demonstrate
hypertrophy?
A. Number of cells
B. Size of cells
C. Type of cells
D. Function of cells
Correct Answer: B
Rationale: Hypertrophy is an increase in the size of individual cells, not the number of
cells. Hyperplasia is an increase in cell number.
Question 9
The overall process of adaptive change necessary to maintain survival and well-being is:
A. Homeostasis
B. Allostasis
C. Acclimatization
D. Stress response
Correct Answer: B
Rationale: Allostasis is the process of achieving stability through physiological and
behavioral changes in response to stress. Homeostasis is maintaining a stable internal
environment.
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