NUR 521 ADV PHARM EXAM 2 NEWEST 2026/2027 COMPLETE
QUESTIONS AND CORRECT ANSWERS (VERIFIED ANSWERS)
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The following is true for drugs used to alleviate alcohol withdrawal symptoms:
A. Diazepam for patients with compromised liver function
B. Lorazepam for long-acting, "built-in tapering" effect
C. Eszopiclone to avoid "hangover" effects
D. All of the above are correct
E. None of the above are correct - ANSWER-e. None of the above are correct
(A.diazepam for patients with compromised liver function, No-long
half-life will cause accumulation in patients with compromised livers B.
Lorazepam for long-acting, "built-in tapering" effect, No-lorazepam has
short half-life for use in patients with liver disease C. Eszopiclone to
avoid "hangover" effects, No-not useful for this purpose)
T/F: Genetic variants that increase the metabolism of ethanol to
acetaldehyde and decrease the metabolism rate of acetaldehyde to acetate
are protective against alcohol-use disorders - ANSWER-True
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Support of the monoamine hypothesis of major depression is based on the
observation(s) that:
A. Inhibition of norepinephrine synthesis causes depression symptoms in
patients who respond to noradrenergic drugs.
B. Depressed patients who respond to serotonergic antidepressants are
more likely to suffer relapse when given trytophan-free diets.
C. All classes of antidepressants appear to decrease the synaptic availability
of monoamines
D. All of the above are correct
E. Only A and B are correct - ANSWER-E. Only A and B are correct
(C. All classes of antidepressants appear to decrease the synaptic
availability of monoamines. NO, they increase the synaptic availability
of monoamines)
Monoamine oxidase inhibitors (maois):
A. Are used to block serotonin syndrome in patients taking ssris and snris
B. Have more sexual side effects than other antidepressants
C. Act by decreasing monoamine content in neurons
D. All of the above are correct
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E. None of the above are correct - ANSWER-B. Have more sexual side
effects than other antidepressants
(A. Are used to block serotonin syndrome in patients taking ssris NO,
maois cause serotonin syndrome in patients taking ssris; C. Act by
decreasing monoamine content in neurons NO, maois increase
monoamine content by inhibiting the enzymatic degradation of
monoamines)
. Antidepressant drugs in the tricyclic antidepressant (TCA) class:
A. Are commonly used for some pain disorders
B. Are dosed at night due to sedating effects
C. Are associated with discontinuation syndrome
D. All of the above are correct
E. None of the above are correct - ANSWER-D. All of the above are correct
In addition to treating major depressive disorder, antidepressants are also
used for:
A. Anxiety disorders
B. Pain disorders
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C. Premenstrual dysphoric disorder (PMDD)
D. All of the above are correct
E. None of the above are correct - ANSWER-D. All of the above are correct
All currently available drugs for the treatment of major depression function
by one or more mechanisms of action including:
A. Inhibition of the enzymatic synthesis of monoamines
B. Activation of the activity of the serotonin transporter, norepinephrine
transporter, or both C. Inhibition of inositol signaling
D. Only A and B are correct
E. None of the above are correct - ANSWER-E. None of the above are
correct
(A. Inhibition of the enzymatic synthesis of monoamines, NO, inhibition
of the enzymatic degradation of monoamines B. Activation of the
activity of the serotonin transporter, norepinephrine transporter, or
both, NO, the inhibition of the activity of... C. Inhibition of inositol
signaling, NO, this is the mechanism of lithium in treating bipolar
disorder D. Only A and B are)