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Rationales 2025/2026 Q&A | Instant
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1. Pharmacology is the study of:
A. Disease prevention
B. Drug actions and effects in the body
C. Surgical procedures
D. Diagnostic imaging
Answer: B
Rationale: Pharmacology focuses on how drugs work, their effects, uses, adverse
reactions, and movement through the body.
2. Pharmacokinetics refers to:
A. What the drug does to the body
B. What the body does to the drug
C. Drug prescribing laws
D. Drug classifications only
Answer: B
Rationale: Pharmacokinetics includes absorption, distribution, metabolism, and
excretion (ADME).
3. Pharmacodynamics describes:
,A. Drug pricing
B. Drug absorption
C. What the drug does to the body
D. Drug elimination
Answer: C
Rationale: Pharmacodynamics examines the biological and physiological effects of
drugs.
4. The process by which a drug enters the bloodstream is:
A. Distribution
B. Metabolism
C. Absorption
D. Excretion
Answer: C
Rationale: Absorption is the movement of a drug from the administration site into
systemic circulation.
5. The primary organ responsible for drug metabolism is the:
A. Kidney
B. Liver
C. Lung
D. Pancreas
Answer: B
Rationale: Most drug metabolism occurs in the liver through enzyme systems
such as CYP450.
6. The primary organ responsible for drug excretion is the:
, A. Heart
B. Stomach
C. Kidney
D. Spleen
Answer: C
Rationale: The kidneys eliminate many drugs and metabolites through urine.
7. Bioavailability refers to:
A. Drug potency
B. Amount of drug reaching systemic circulation
C. Drug toxicity
D. Drug half-life
Answer: B
Rationale: Bioavailability measures the fraction of an administered dose that
reaches circulation unchanged.
8. A drug administered intravenously has a bioavailability of:
A. 25%
B. 50%
C. 75%
D. 100%
Answer: D
Rationale: IV drugs enter the bloodstream directly, resulting in complete
bioavailability.
9. A drug's half-life is the time required for:
A. Complete elimination
B. Half of the drug concentration to be removed