ATI PN Pharmacology
OBJECTIVE ASSESSMENT - EXAM
ATI PN Pharmacology Proctor Exam |
2026/2027 NGN-Style Questions & Case
Studies | Pharmacology ATI (PDF)
2026/2027
Professional Licensing Exam
75 100% 2026/2027
QUESTIONS VERIFIED ANSWERS EDITION
TOPICS COVERED
Drug Classifications & Mechanisms of Action Dosage Calculations & Safe Medication Administration
Cardiac Glycosides, Antihypertensives & Diuretics Insulin, Oral Hypoglycemics & Thyroid Medications
Antibiotics, Antivirals & Antifungal Agents Analgesics, Anticonvulsants & Psychotropic Medications
COVER PAGE - 1
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 1 of 7
, SECTION 1 | Pharmacology Principles | Q1-Q15 | ATI PN Pharmacology Proctor Exam | 2026/2027
Q1 Question 1 of 75
A 68-year-old client with chronic heart failure is prescribed oral furosemide 40 mg
daily. The nurse reviews the client's current medications and notes the client also
takes digoxin 0.25 mg daily and lisinopril 10 mg daily. The nurse recognizes that
concurrent administration of furosemide with digoxin increases the risk of which
adverse effect?
A. Hyperkalemia leading to cardiac dysrhythmias
B. Hypokalemia predisposing to digoxin toxicity
C. Hyponatremia causing central nervous system depression
D. Hypercalcemia resulting in renal stone formation
Correct Answer: B
Rationale:
Furosemide is a loop diuretic that promotes potassium excretion, leading to hypokalemia. Hypokalemia
increases myocardial sensitivity to digoxin, significantly raising the risk of digoxin toxicity even at
therapeutic serum levels. The nurse should monitor potassium levels closely and consider potassium
supplementation.
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 1 of 7
, SECTION 1 | Pharmacology Principles | Q1-Q15 | ATI PN Pharmacology Proctor Exam | 2026/2027
Q2 Question 2 of 75
A nurse is preparing to administer an intramuscular injection of ceftriaxone 1 g to an
adult client. The nurse selects the appropriate needle length and reviews the
medication label, which indicates a recommended injection site of the ventrogluteal
muscle. The nurse understands that the ventrogluteal site is preferred over the
dorsogluteal site primarily because it:
A. Allows for faster absorption of lipophilic medications
B. Contains fewer blood vessels and no major nerves, reducing injury risk
C. Accommodates larger medication volumes up to 5 mL safely
D. Is more accessible for self-administration by the client
Correct Answer: B
Rationale:
The ventrogluteal site is the preferred intramuscular injection site because it is free of major nerves and
blood vessels, minimizing the risk of sciatic nerve injury or vascular damage. The dorsogluteal site
carries significant risk of sciatic nerve injury and is no longer recommended as a primary injection site.
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 2 of 7
, SECTION 1 | Pharmacology Principles | Q1-Q15 | ATI PN Pharmacology Proctor Exam | 2026/2027
Q3 Question 3 of 75
A client with a history of peptic ulcer disease is prescribed ibuprofen 600 mg every 6
hours for osteoarthritis pain. The nurse recognizes that ibuprofen is a nonselective
NSAID and should instruct the client to take the medication with food to reduce the
risk of:
A. Hepatotoxicity from first-pass metabolism
B. Gastrointestinal mucosal irritation and ulceration
C. Nephrotoxicity from prostaglandin inhibition
D. Ototoxicity affecting the cochlear hair cells
Correct Answer: B
Rationale:
Ibuprofen is a nonselective NSAID that inhibits both COX-1 and COX-2 enzymes. Inhibition of COX-1
reduces protective gastric prostaglandins, leading to gastric mucosal irritation, erosion, and potential
ulceration. Taking NSAIDs with food helps buffer gastric acid and reduce direct mucosal irritation.
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 3 of 7
OBJECTIVE ASSESSMENT - EXAM
ATI PN Pharmacology Proctor Exam |
2026/2027 NGN-Style Questions & Case
Studies | Pharmacology ATI (PDF)
2026/2027
Professional Licensing Exam
75 100% 2026/2027
QUESTIONS VERIFIED ANSWERS EDITION
TOPICS COVERED
Drug Classifications & Mechanisms of Action Dosage Calculations & Safe Medication Administration
Cardiac Glycosides, Antihypertensives & Diuretics Insulin, Oral Hypoglycemics & Thyroid Medications
Antibiotics, Antivirals & Antifungal Agents Analgesics, Anticonvulsants & Psychotropic Medications
COVER PAGE - 1
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 1 of 7
, SECTION 1 | Pharmacology Principles | Q1-Q15 | ATI PN Pharmacology Proctor Exam | 2026/2027
Q1 Question 1 of 75
A 68-year-old client with chronic heart failure is prescribed oral furosemide 40 mg
daily. The nurse reviews the client's current medications and notes the client also
takes digoxin 0.25 mg daily and lisinopril 10 mg daily. The nurse recognizes that
concurrent administration of furosemide with digoxin increases the risk of which
adverse effect?
A. Hyperkalemia leading to cardiac dysrhythmias
B. Hypokalemia predisposing to digoxin toxicity
C. Hyponatremia causing central nervous system depression
D. Hypercalcemia resulting in renal stone formation
Correct Answer: B
Rationale:
Furosemide is a loop diuretic that promotes potassium excretion, leading to hypokalemia. Hypokalemia
increases myocardial sensitivity to digoxin, significantly raising the risk of digoxin toxicity even at
therapeutic serum levels. The nurse should monitor potassium levels closely and consider potassium
supplementation.
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 1 of 7
, SECTION 1 | Pharmacology Principles | Q1-Q15 | ATI PN Pharmacology Proctor Exam | 2026/2027
Q2 Question 2 of 75
A nurse is preparing to administer an intramuscular injection of ceftriaxone 1 g to an
adult client. The nurse selects the appropriate needle length and reviews the
medication label, which indicates a recommended injection site of the ventrogluteal
muscle. The nurse understands that the ventrogluteal site is preferred over the
dorsogluteal site primarily because it:
A. Allows for faster absorption of lipophilic medications
B. Contains fewer blood vessels and no major nerves, reducing injury risk
C. Accommodates larger medication volumes up to 5 mL safely
D. Is more accessible for self-administration by the client
Correct Answer: B
Rationale:
The ventrogluteal site is the preferred intramuscular injection site because it is free of major nerves and
blood vessels, minimizing the risk of sciatic nerve injury or vascular damage. The dorsogluteal site
carries significant risk of sciatic nerve injury and is no longer recommended as a primary injection site.
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 2 of 7
, SECTION 1 | Pharmacology Principles | Q1-Q15 | ATI PN Pharmacology Proctor Exam | 2026/2027
Q3 Question 3 of 75
A client with a history of peptic ulcer disease is prescribed ibuprofen 600 mg every 6
hours for osteoarthritis pain. The nurse recognizes that ibuprofen is a nonselective
NSAID and should instruct the client to take the medication with food to reduce the
risk of:
A. Hepatotoxicity from first-pass metabolism
B. Gastrointestinal mucosal irritation and ulceration
C. Nephrotoxicity from prostaglandin inhibition
D. Ototoxicity affecting the cochlear hair cells
Correct Answer: B
Rationale:
Ibuprofen is a nonselective NSAID that inhibits both COX-1 and COX-2 enzymes. Inhibition of COX-1
reduces protective gastric prostaglandins, leading to gastric mucosal irritation, erosion, and potential
ulceration. Taking NSAIDs with food helps buffer gastric acid and reduce direct mucosal irritation.
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 3 of 7
