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Terms in this set (383)
Medication Assisted Treatment any treatment for for a SUD that includes a
(MAT) pharmacologic intervention as part of a
comprehensive substance abuse treatment
plan with ultimate goal of patient recovery
with full social function
,alcohol dependence FDA approved disulfiram, naltrexone, and
acamprosate for treatment of ____________
opioid dependence FDA approved methadone, naltrexone, and
buprenorphine for treatment of _____________
alcohol, nicotine and opioid currently, FDA has approved medications
effective for MAT in three types of SUD:
_____________, _____________ and __________ dependence
acamprosate, disulfiram, three drugs approved for alcohol
naltrexone dependence
,Acamprosate (Campral) used to treat alcohol dependence; reduces
symptoms of protracted withdrawal (i.e.
insomnia, anxiety, restlessness, and dysphoria)
by normalizing brain systems disrupted by
chronic alcohol consumption; more effective
in pts with severe alcohol use disorders
Disulfiram (Antabuse) used to treat alcohol dependence; inhibits an
enzyme involved in the metabolism in
alcohol, causing unpleasant reaction (i.e.
flushing, nausea, and heart palpitations) if
alcohol is consumed after taking the
medication; compliance can be a problem
but is very effective with motivated pts.
, Naltrexone (Vivitrol or Revia) used to treat alcohol dependence; blocks
receptors involved in rewarding effects of
drinking and in cravings for alcohol. Reduces
relapse of heavy drinking behavior and is
highly effective in some but not all pts., where
varied outcomes could be due to genetic
factors. Available in both oral tablet and long-
acting injectable form
Methadone, Buprenorphine, three FDA approved drugs used in MAT for
Naltrexone opioid use disorders
Methadone prevents opioid withdrawal and craving
symptoms by activating opiate receptors in
the brain. Long history of use in treatment of
opioid dependence.