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ATI RN Targeted Medical-Surgical: Practice Questions & Answers with Rationales (100 Qs)

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This comprehensive ATI RN Targeted Medical-Surgical study guide features 100 exam-style questions with detailed rationales covering all core med-surg content areas: Respiratory (emphysema dyspnea barrel chest clubbing, pneumonia treatment effectiveness, ABG respiratory acidosis pH 7.30 PaCO2 50, pulmonary embolism chest pain dyspnea emergency, postural drainage timing 1 hour before meals, TB hemoptysis, MDI with spacer hold breath 10 seconds), Endocrine (DKA priority IV fluids, thyroidectomy stridor emergency tracheostomy, hyperthyroidism tachycardia, type 1 diabetes hypoglycemia orange juice 15g carbs, SIADH hyponatremia, Addison's disease hypotension crisis, diabetes foot care well-fitting shoes), Cardiovascular (heart failure peripheral edema JVD, hypertension limit saturated fats, nitroglycerin effective decreased BP, digoxin toxicity nausea check vitals, verapamil avoid grapefruit juice, warfarin monitor PT/INR, cardiac cath dampness under buttocks bleeding, MI troponin I), Renal/Urinary (KUB x-ray detects kidney stones, 24-hour urine discard first void, kidney biopsy greatest risk hemorrhage, CT contrast allergic reaction hives, hemodialysis restores electrolyte balance, post-dialysis care check BUN administer withheld meds monitor bleeding no BP on AV access, CKD restrict protein, acute kidney injury oliguric phase K+ 6.2 hyperkalemia priority), Gastrointestinal (cholecystectomy purulent drainage infection, colostomy skin care warm water mild soap, NG tube greenish-yellow drainage functioning, appendicitis sudden pain relief rupture emergency, GERD avoid eating 3 hours before bedtime, colostomy stoma dark purple ischemia emergency, CPM machine administer analgesic 30 min prior), Musculoskeletal (hip arthroplasty pillow between legs prevent dislocation, fat embolism syndrome petechiae on chest, cast numbness tingling compartment syndrome, osteoporosis canned sardines with bones calcium), Neurological (increased ICP widening pulse pressure Cushing's triad, stroke dysphagia HOB 90 degrees, myasthenia gravis cholinergic crisis weakness fasciculations salivation, head injury diabetes insipidus large volume dilute urine, Guillain-Barré vital capacity 15 mL/kg respiratory failure, Parkinson's resting tremor), Hematology/Oncology (epoetin alfa effective decreased fatigue, anemia pallor fatigue dyspnea, gentamicin ototoxicity tinnitus dizziness, DIC decreased urine output, leukemia fever 102°F infection neutropenia, thrombocytopenia use electric razor), Fluid/Electrolytes/ABGs (hyponatremia weakness confusion, hyperkalemia tall peaked T waves, hypocalcemia positive Trousseau's sign, metabolic alkalosis hypoventilation), Perioperative/Leadership/Safety (informed consent sign before pre-op meds, hearing aids kept in surgery, PACU respiratory depression RR 10 shallow priority, post-op restlessness confusion hypovolemia or hypoxia, PCA pump assess pain and sedation, fire safety RACE do not open doors/windows, disaster triage red tag tension pneumothorax, acetaminophen overdose monitor LFTs, radiation disaster potassium iodide only for radioactive iodine), Pharmacology (heparin SQ abdomen 2 inches from umbilicus, furosemide effective decreased dyspnea, morphine PCA respiratory rate 10 adverse effect, insulin rotate sites, nitroglycerin three doses 5 min apart, vancomycin red man syndrome stop infusion), Wound/Burn/Skin (pressure ulcer stage 3 subcutaneous fat visible, burn resuscitation urine output 30 mL/hr adequate, shingles vesicular rash dermatome, melanoma ABCDE asymmetrical irregular borders, cataract extraction no heavy lifting), Ear/Eye (Meniere's triad tinnitus vertigo hearing loss, open-angle glaucoma gradual peripheral vision loss, eye drops look up toward ceiling). Perfect for RN nursing students preparing for ATI RN Medical-Surgical proctored exams, NCLEX-RN, or med-surg final exams — all answers include correct options + detailed rationales.

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ATI RN TARGETED MEDICAL-SURGICAL
EXAM QUESTIONS AND ANSWERS WITH
RATIONALES LATEST EXAM UPDATE


.

1. A nurse is collecting data from a client who has emphysema. Which of the following
findings should the nurse expect? (Select all that apply.)
A. Dyspnea

B. Barrel chest

C. Clubbing of the fingers

D. Shallow respirations

E. Bradycardia


Answer: A, B, C, D

Rationale: In emphysema, dyspnea, barrel chest, clubbing of the fingers, and shallow
respirations are expected. Tachycardia, not bradycardia, occurs as the heart compensates for
low oxygen levels .

2. A nurse is caring for a client with pneumonia who has been receiving IV antibiotics.
Which assessment finding indicates treatment is effective?
A. Diminished breath sounds in all lung fields

B. Client reports increased dyspnea

C. Client reports improvement in cough and energy levels

D. Chest x-ray shows increased infiltrates



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,Answer: C. Client reports improvement in cough and energy levels

Rationale: Subjective improvement in symptoms such as cough and energy levels indicates a
positive response to antibiotic therapy. Objective data should also show improved breath sounds
and clearing of infiltrates .

3. A nurse is interpreting arterial blood gas (ABG) results for a client. Which values
indicate respiratory acidosis?
A. pH 7.50, PaCO2 30, HCO3 24 B.
pH 7.30, PaCO2 50, HCO3 24

C. pH 7.35, PaCO2 45, HCO3 28

D. pH 7.25, PaCO2 40, HCO3 15


Answer: B. pH 7.30, PaCO2 50, HCO3 24

Rationale: Respiratory acidosis is indicated by a low pH (<7.35) and an elevated PaCO2 (>45).
HCO3 remains normal in the acute phase .

4. A nurse is caring for a client with a pulmonary embolism. Which finding should the
nurse report immediately? A. Heart rate of 100/min
B. Respiratory rate of 24/min

C. Oxygen saturation of 91% on room air

D. Sudden onset of chest pain and dyspnea


Answer: D. Sudden onset of chest pain and dyspnea

Rationale: Sudden chest pain and dyspnea indicate worsening of the pulmonary embolism and
potential hemodynamic compromise. This requires immediate intervention.

5. A nurse is providing postural drainage for a client with bronchiectasis. Which action
should the nurse take?
A. Perform treatment immediately after meals

B. Schedule treatment 1 hour before meals or 3 hours after meals


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,C. Limit treatment to 5 minutes per position

D. Place client in supine position for all drainage


Answer: B. Schedule treatment 1 hour before meals or 3 hours after meals *Rationale:
Postural drainage should be scheduled away from mealtimes to prevent nausea, vomiting, and
aspiration. It's typically done before meals or at least 1-2 hours after eating.*

6. A nurse is assessing a client with suspected tuberculosis. Which finding is most
significant?
A. Night sweats

B. Persistent cough with blood-tinged sputum

C. Low-grade fever

D. Weight gain


Answer: B. Persistent cough with blood-tinged sputum

Rationale: While all symptoms may be present, a persistent cough with hemoptysis (bloodtinged
sputum) is a classic and concerning finding that warrants further investigation for TB.

7. A nurse is caring for a client receiving oxygen at 6 L/min via nasal cannula.
Which finding indicates adequate oxygenation?
A. Oxygen saturation of 88%

B. Oxygen saturation of 94%

C. Respiratory rate of 28/min

D. Use of accessory muscles


Answer: B. Oxygen saturation of 94%

Rationale: Oxygen saturation should generally be maintained at 94% or higher for most clients.
88% is too low, and tachypnea with accessory muscle use indicates respiratory distress.




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, 8. A nurse is teaching a client with asthma how to use a metered-dose inhaler (MDI)
with a spacer. Which step is correct? A. Inhale quickly and forcefully
B. Hold breath for 10 seconds after inhalation

C. Exhale into the spacer

D. Activate the inhaler at the end of exhalation


Answer: B. Hold breath for 10 seconds after inhalation

Rationale: Holding the breath for up to 10 seconds allows the medication to deposit in the
airways. Inhalation should be slow and deep, and the inhaler is activated at the beginning of
inspiration .

9. A nurse is caring for a client with diabetic ketoacidosis (DKA). Which
intervention should the nurse prioritize? A. Administer intravenous regular
insulin
B. Encourage the client to drink oral fluids

C. Begin intravenous fluids with normal saline

D. Provide oxygen via nasal cannula

Answer: C. Begin intravenous fluids with normal saline

Rationale: The first priority in DKA management is fluid replacement to correct dehydration and
restore perfusion. Once fluids are initiated, insulin therapy can safely follow .

10. A nurse is monitoring a client who had a thyroidectomy. The client suddenly develops
stridor, difficulty breathing, and restlessness. Which action should the nurse take first?
A. Administer calcium gluconate

B. Prepare for emergency tracheostomy

C. Place the client in high-Fowler's position

D. Notify the healthcare provider immediately


Answer: B. Prepare for emergency tracheostomy


Page 4 of 39

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