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Table of Contents
Table of Contents 1
Chapter 01 - Introduction to Drugs 3
Chapter 02 - Drugs and the Body 21
Chapter 03 - Toxic Effects of Drugs 38
Chapter 04 - The Nursing Process in Drug Therapy and PatienSafety J 55
Chapter 05 - Dosage Calculations 72
Chapter 06 - Challenges to Effective Drug Therapy 86
Chapter 07 - Introduction to Cell Physiology 103
Chapter 08 - Antiinfective Agents 119
Chapter 09 - Antibiotics 137
Chapter 10 - Antiviral Agents 155
Chapter 11 - Antifungal Agents 171
Chapter 12 - Antiprotozoal Agents 187
Chapter 13 - Anthelmintic Agents 203
Chapter 14 - Antineoplastic Agents 218
Chapter 15 - Introduction to the Immune Response and Inflammation
235
Chapter 16 - Antiinflammatory, Antiarthritis, and Related Agents 252
Chapter 17 - Immune Modulators 268
Chapter 18 - Vaccines and Sera 285
Chapter 19 - Introduction to Nerves and the Nervous System 302
Chapter 20 - Anxiolytic and Hypnotic Agents 318
Chapter 21 - Antidepressan Agents J 335
Chapter 22 - Psychotherapeutic Agents 352
Chapter 23 - Antiseizure Agents 368
Chapter 24 - Antiparkinsonism Agents 384
Chapter 25 - Muscle Relaxants 399
Chapter 26 - Opioid Agonists, Opioid Antagonists, and Antimigraine
Agents 414
Chapter 27 - General and Local Anesthetic Agents 429
Chapter 28 - Neuromuscular Junction Blocking Agents 445
Chapter 29 - Introduction to the Autonomic Nervous System 461
Chapter 30 - Adrenergic Agonists 477
Chapter 31 - Adrenergic Antagonists 492
Chapter 32 - Cholinergic Agonists 508
Chapter 33 - Anticholinergic Agents 524
Chapter 34 - Introduction to the Endocrine System 540
Chapter 35 - Hypothalamic and Pituitary Agents 554
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Chapter 36 - Adrenocortical Agents 569
Chapter 37 - Thyroid and Parathyroid Agents 585
Chapter 38 - Agents to Control Blood Glucose Levels 601
Chapter 39 - Introduction to the Reproductive System 617
Chapter 40 - Drugs Affecting the Female Reproductive System 634
Chapter 41 - Drugs Affecting the Male Reproductive System 650
Chapter 42 - Introduction to the Cardiovascular System 666
Chapter 43 - Drugs Affecting Blood Pressure 682
Chapter 44 - Agents for Treating Hear Failure Chapter
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699
45 - Antiarrhythmic Agents 714
Chapter 46 - Antianginal Agents 730
Chapter 47 - Lipid-Lowering Agents 745
Chapter 48 - Drugs Affecting Blood Coagulation 761
Chapter 49 - Drugs Used to Trea Anemias ChapterJ
776
50 - Introduction to the Renal System Chapter 51 - 791
Diuretic Agents 806
Chapter 52 - Drugs Affecting the Urinary Tracand the Bladder J
821
Chapter 53 - Introduction to the Respiratory System 837
Chapter 54 - Drugs Acting on the Upper Respiratory Trac J
853
Chapter 55 - Drugs Acting on the Lower Respiratory Trac J
869
Chapter 56 - Introduction to the Gastrointestinal System 885
Chapter 57 - Drugs Affecting Gastrointestinal Secretions 900
Chapter 58 - Drugs Affecting Gastrointestinal Motility 914
Chapter 59 - Antiemetic Agents 929
Chapter 60 - Vitamin, Minerals, and Complementary/Alternative
Medications 943
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Chapter 01 - Introduction to Drugs
1. A nurse working in radiology administers iodine to a patient who is having a
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computed tomography (CT) scan. The nurse working on the oncology unit
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administers chemotherapy to patients who have cancer. Atthe Public Health
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Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to a
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14-month-old child as a routine immunization. Which branch of pharmacology
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best describes the actions of all three nurses?
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A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
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Pharmacology isthestudy of thebiologic effectsof chemicals. Nursesareinvolved J J J J J J J J J J J J J
with clinical pharmacology or pharmacotherapeutics, which is a branch of
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pharmacology thatdealswiththeusesofdrugs totreat, prevent, and diagnose J J J J J J J J J J J J J
disease. The radiology nurse is administering a drug to help diagnose adisease.
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Theoncology nurseisadministering adrug to helptreata disease.
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Pharmacoeconomics includes any costs involved in drug therapy. J J J J J J J
Pharmacodynamicsinvolveshowadrugaffectsthebodyand pharmacokineticsis J J J J J J J J J J J
howthebodyactsonthebody.
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2. Aphysician hasorderedintramuscular (IM) injections of morphine, a narcotic,
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every 4hours asneeded forpainin a motor vehicleaccident victim. Thenurse is
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aware this drug has a high abuse potential. Under what category would morphine
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beclassified?
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A) Schedule I J
B) Schedule II J
C) Schedule III J
D) Schedule IV J
Ans: B
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Narcotics with a high abuse potential are classified as Schedule II drugs because of
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severe dependence liability. Schedule I drugs have high abuse potentialandno
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acceptedmedical use.Schedule IIIdrugshave alesser abuse potential than II and an
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accepted medical use. Schedule IV drugs have low abuse potential and limited
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dependence liability. J
3. When involved in phase III drug evaluation studies, what responsibilities would the
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nursehave? J
A) Workingwith animalswhoaregiven experimental drugs J J J J J J J
B) Choosing appropriate patients to beinvolved in the drug study J J J J J J J J J
C) Monitoring andobserving patientsclosely for adverse effects J J J J J J J
D) Conducting research todetermine effectiveness ofthedrug J J J J J J J J
Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in which patients
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areasked torecordanysymptomsthey experience whiletakingthe drugs. Nurses
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may be responsible for helping collect and analyze the information to be shared
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with the Food and Drug Administration (FDA) but would notconductresearch
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independently because nursesdonotprescribe medications. Use of animals in J J J J J J J J J J J
drug testing is done in the preclinical trials.
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Selectpatientswhoareinvolved inphase II studiesto participate instudies where the
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participants have the disease the drug is intended to treat. These patients are
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monitored closely for drugaction andadverse effects.Phase I studiesinvolve
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healthy human volunteers whoareusuallypaid for their participation. Nurses may
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observe for adverse effects and toxicity. J J J J J
4. What concept isconsidered whengeneric drugsare substituted forbrand
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namedrugs? J
A) Bioavailability
B) Critical concentration J
C) Distribution
D) Half-life
Ans: A
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