ATI PHARMACOLOGY PROCTORED STUDY
GUIDE 2026 COMPREHENSIVE QUESTIONS
AND STEP BY STEP SOLUTIONS
◉ Medications Affecting Blood Pressure: Vasodilators
Answer: Nitroprusside: Hypertensive crisis
- C: Pregnancy/lactation, heart failure, liver/renal disease
- AE: Hypotension, cyanide poinsoning, bradycardia, tachycardia
- NC: Administered IV, continuous monitoring of vital signs and ECG
◉ Medications Affecting Blood Pressure: Beta-adrenergic Blockers
Answer: Metoprolol, Atenelol, Propranalol, Carvedilol: Hypertension,
Angina, tachydysrhythmias, heart failure, MI
- C: Pregnancy/lactation, AV block, bradycardia, hypotension,
asthma
- AE: Bradycardia, decreased CO, AV block, ortho. hypo,
bronchoconstriction
- NC: Monitor pulse and hold if <60, may mask hypoglycemia
symptoms, monitor for orthostasis
◉ Cardiac Glycosides and Heart Failure: Cardiac Glycosides
Answer: Digoxin: Heart failure
,- C: Pregancy/lactation, V-fib, V-tach, heart block
- AE: Cardiotoxicity, nausea, vomiting, abdominal pain, fatigue,
weakness, blurred vision
- NC: Monitor for signs of toxicity (0.6-1.2), monitor for bradycardia,
avoid taking OTC medications to prevent adverse effects
◉ Cardiac Glycosides and Heart Failure: Adrenergic Agonists
Answer: Epinephrine: Anaphylactic shock, bronchodilation,
management of superficial bleeding, slows absorption of local
anesthetics
- C: Hyperthyroidism, angina, hypertension
- AE: Hypertension, dysrhythmias, tachycardia
- NC: Monitor ECG and BP, monitor for hyerglycemia in diabetics
Dobutamine: Heart failure
- C: Hyperthyroidism, angina, hypertension
- AE: Hypertension, dysrhythmias, tachycardia
- NC: Administered IV, monitor ECG and BP, older adults are more
likely to experience adverse effects
Dopamine: Heart failure, shock, acute kidney injury
- C: Hyperthyroidism, angina, hypertension
- AE: Hypertension, dysrhythmias, tachycardia
, - NC: Administered IV, monitor ECG and BP, monitor urine output
◉ Medications Affecting Cardiac Rhythm: Organic Nitrates
Answer: Nitroglycerin, Isosorbide, Dinitrate: Acute angina,
prophylaxis for chronic stable angina
- C: Hypersensitivity, glaucoma, don't take with erectile dysfunction
meds.
- AE: Headache, ortho. hypo, reflex tachycardia
- NC: Can be given sublingually, Take 1 tablet at the first sign of chest
pain - may take a max of 3 pills every 5 minutes, go to the ER if the
pain doesn't stop.
◉ Medications Affecting Cardiac Rhythm: Antianginal Agents
Answer: Ranolazine: Chronic Stable Angina
- C: Pregnancy, QT interval prolongation, hepatic impairment,
ventricular dysrhythmias
- AE: QT prolongation, elevated BP
- NC: Administer as extended release tablet, obtain ECG
◉ Medications Affecting Cardiac Rhythm: Antidysrhythmic Agents
(1A)
Answer: Procainamide: A-fib, A-flutter, V-tach
- C: Complete heart block, systemic lupus, liver/kidney disease
GUIDE 2026 COMPREHENSIVE QUESTIONS
AND STEP BY STEP SOLUTIONS
◉ Medications Affecting Blood Pressure: Vasodilators
Answer: Nitroprusside: Hypertensive crisis
- C: Pregnancy/lactation, heart failure, liver/renal disease
- AE: Hypotension, cyanide poinsoning, bradycardia, tachycardia
- NC: Administered IV, continuous monitoring of vital signs and ECG
◉ Medications Affecting Blood Pressure: Beta-adrenergic Blockers
Answer: Metoprolol, Atenelol, Propranalol, Carvedilol: Hypertension,
Angina, tachydysrhythmias, heart failure, MI
- C: Pregnancy/lactation, AV block, bradycardia, hypotension,
asthma
- AE: Bradycardia, decreased CO, AV block, ortho. hypo,
bronchoconstriction
- NC: Monitor pulse and hold if <60, may mask hypoglycemia
symptoms, monitor for orthostasis
◉ Cardiac Glycosides and Heart Failure: Cardiac Glycosides
Answer: Digoxin: Heart failure
,- C: Pregancy/lactation, V-fib, V-tach, heart block
- AE: Cardiotoxicity, nausea, vomiting, abdominal pain, fatigue,
weakness, blurred vision
- NC: Monitor for signs of toxicity (0.6-1.2), monitor for bradycardia,
avoid taking OTC medications to prevent adverse effects
◉ Cardiac Glycosides and Heart Failure: Adrenergic Agonists
Answer: Epinephrine: Anaphylactic shock, bronchodilation,
management of superficial bleeding, slows absorption of local
anesthetics
- C: Hyperthyroidism, angina, hypertension
- AE: Hypertension, dysrhythmias, tachycardia
- NC: Monitor ECG and BP, monitor for hyerglycemia in diabetics
Dobutamine: Heart failure
- C: Hyperthyroidism, angina, hypertension
- AE: Hypertension, dysrhythmias, tachycardia
- NC: Administered IV, monitor ECG and BP, older adults are more
likely to experience adverse effects
Dopamine: Heart failure, shock, acute kidney injury
- C: Hyperthyroidism, angina, hypertension
- AE: Hypertension, dysrhythmias, tachycardia
, - NC: Administered IV, monitor ECG and BP, monitor urine output
◉ Medications Affecting Cardiac Rhythm: Organic Nitrates
Answer: Nitroglycerin, Isosorbide, Dinitrate: Acute angina,
prophylaxis for chronic stable angina
- C: Hypersensitivity, glaucoma, don't take with erectile dysfunction
meds.
- AE: Headache, ortho. hypo, reflex tachycardia
- NC: Can be given sublingually, Take 1 tablet at the first sign of chest
pain - may take a max of 3 pills every 5 minutes, go to the ER if the
pain doesn't stop.
◉ Medications Affecting Cardiac Rhythm: Antianginal Agents
Answer: Ranolazine: Chronic Stable Angina
- C: Pregnancy, QT interval prolongation, hepatic impairment,
ventricular dysrhythmias
- AE: QT prolongation, elevated BP
- NC: Administer as extended release tablet, obtain ECG
◉ Medications Affecting Cardiac Rhythm: Antidysrhythmic Agents
(1A)
Answer: Procainamide: A-fib, A-flutter, V-tach
- C: Complete heart block, systemic lupus, liver/kidney disease
