Pharmacokinetic changes with aging is reflective of:
A. What the drug does to the body
B. What the body does to the drug
C. The effect at the site of action and the time and intensity of the drug
D. The side effects commonly associated with the drug
B. What the body does to the drug
All the following statements are false about drug absorption except:
A. Antacids increase the bioavailability of digitalis
B. Gastric acidity decreases with age
C. Anticholinergics increase colonic motility
D. Underlying chronic disease has little impact on drug absorption
D. Underlying chronic disease has little impact on drug absorption
,All of the following statements are true about drug distribution in the elderly except:
A. Drugs distributed in water have lower concentration
B. Drugs distributed in fat have less intense, more prolonged effect
C. Drugs highly protein bound have greater potential to cause an adverse drug reaction
D. The fastest way to deliver a drug to the action site is by inhalation
A. Drugs distributed in water have lower concentration
Men have faster and more efficient biotransformation of drugs and this is thought to be due
to:
A. Less obesity rates than women
B. Prostate enlargement
C. Testosterone
D. Less estrogen than women
C. Testosterone
,The cytochrome p system involves enzymes that are generally:
A. Inhibited by drugs
B. Induced by drugs
C. Inhibited or induced by drugs
D. Associated with decreased liver perfusion
C. Inhibited or induced by drugs
A statement not shown to be true about pharmacodynamics changes with aging is:
A. Decreased sensitivity to oral anticoagulants
B. Enhanced sensitivity to central nervous system drugs
C. Drug responsiveness can be influenced by patient activity level
D. There is a decreased sensitivity to beta blockers
A. Decreased sensitivity to oral anticoagulants
, Atypical presentation of disease in the elderly is reflected by all the following except:
A. Infection without fever
B. Depression without dysphoric mood
C. Myocardial infarction with chest pain and diaphoresis
D. Cardiac manifestations of thyroid disease
C. Myocardial infarction with chest pain and diaphoresis
Functional abilities are best assessed by:
A. Self-report of function
B. Observed assessment of function
C. A comprehensive head-to-toe examination
D. Family report of function
B. Observed assessment of function
A. What the drug does to the body
B. What the body does to the drug
C. The effect at the site of action and the time and intensity of the drug
D. The side effects commonly associated with the drug
B. What the body does to the drug
All the following statements are false about drug absorption except:
A. Antacids increase the bioavailability of digitalis
B. Gastric acidity decreases with age
C. Anticholinergics increase colonic motility
D. Underlying chronic disease has little impact on drug absorption
D. Underlying chronic disease has little impact on drug absorption
,All of the following statements are true about drug distribution in the elderly except:
A. Drugs distributed in water have lower concentration
B. Drugs distributed in fat have less intense, more prolonged effect
C. Drugs highly protein bound have greater potential to cause an adverse drug reaction
D. The fastest way to deliver a drug to the action site is by inhalation
A. Drugs distributed in water have lower concentration
Men have faster and more efficient biotransformation of drugs and this is thought to be due
to:
A. Less obesity rates than women
B. Prostate enlargement
C. Testosterone
D. Less estrogen than women
C. Testosterone
,The cytochrome p system involves enzymes that are generally:
A. Inhibited by drugs
B. Induced by drugs
C. Inhibited or induced by drugs
D. Associated with decreased liver perfusion
C. Inhibited or induced by drugs
A statement not shown to be true about pharmacodynamics changes with aging is:
A. Decreased sensitivity to oral anticoagulants
B. Enhanced sensitivity to central nervous system drugs
C. Drug responsiveness can be influenced by patient activity level
D. There is a decreased sensitivity to beta blockers
A. Decreased sensitivity to oral anticoagulants
, Atypical presentation of disease in the elderly is reflected by all the following except:
A. Infection without fever
B. Depression without dysphoric mood
C. Myocardial infarction with chest pain and diaphoresis
D. Cardiac manifestations of thyroid disease
C. Myocardial infarction with chest pain and diaphoresis
Functional abilities are best assessed by:
A. Self-report of function
B. Observed assessment of function
C. A comprehensive head-to-toe examination
D. Family report of function
B. Observed assessment of function
