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NSG 552 Psychopharmacology – Wilkes University – 2026/2027 – Exam 1 V2 Questions and Verified Answers

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This document contains a comprehensive Exam 1 V2 review for NSG 552 Psychopharmacology at Wilkes University. The material includes practice questions and verified answers covering psychopharmacologic principles, neurotransmitters, pharmacokinetics, pharmacodynamics, antidepressants, anxiolytics, mood stabilizers, antipsychotic medications, and medication management in psychiatric care. The study guide is designed to help nursing students and advanced practice nursing learners prepare for Exam 1 by reinforcing foundational psychopharmacology concepts and clinical decision-making through exam-style practice questions.

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NSG552
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NSG552

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Exam 1 v2: NSG552 / NSG 552 (Latest
Update) Psychopharmacology | Questions and
Verified Answers | 100% Correct | Grade A -
Wilkes



The study of the use of psychotropic medications in the treatment of psychiatric disorders:

Psychopharmacology




The study of what the body does to drugs:

Pharmacokinetics




The study of what the drugs does to the body:

Pharmacodynamics




Involves the absorption, distribution, metabolism and excretion of meds:
First Pass Metabolism (C.Y.P. 450)




Increase serum levels of other drugs that are substrates of that enzyme:

Enzyme inhibitors will slow down metabolism causing toxic levels




Decreases serum levels of other drugs that are substrates of that enzyme:
Enzyme inducers cause fast metabolism and create subtherapeutic drug levels

, Exam 1 v2: NSG552 / NSG 552 (Latest
Update) Psychopharmacology | Questions and
Verified Answers | 100% Correct | Grade A -
Wilkes



Part of the brain that regulates powerful emotions such as fear, rage, sexual desires:

Amygdala




The relay station for sensory information:

Thalamus




Essential for maintaining homeostasis, controls basic needs such as sleep- wake cycles:
Hypothalamus




This lobe is involved in executive functioning, high order planning, speech and motivation:
Frontal Lobe/ Prefrontal cortex




Derived from Tryptophan and made in the Ralphe Nuclei:

Serotonin




Made in the Locus Ceruleus and involved in the noradrenergic pathways:
Norepinephrine

, Exam 1 v2: NSG552 / NSG 552 (Latest
Update) Psychopharmacology | Questions and
Verified Answers | 100% Correct | Grade A -
Wilkes



90% of serotonin receptors are found in the:

GI tract




Produced in the V.T.A. (Reward Pathway) and involved in the four major pathways:

Dopamine




Dopamine inhibits prolactin in this pathway:

Tuberoinfundibular




Increase dopamine in this pathway is associated with positive symptoms:
Mesolimbic Pathway




Decrease dopamine in this pathway is associated with negative symptoms:

Mesocortical Pathway




Decrease dopamine in this pathway produces motor symptoms:
Nigrostriatal Pathway

, Exam 1 v2: NSG552 / NSG 552 (Latest
Update) Psychopharmacology | Questions and
Verified Answers | 100% Correct | Grade A -
Wilkes



Main inhibitory neurotransmitter that induces calmness and relaxation:

Gamma- aminobutyric acid (GABA), Off switch




Main excitatory neurotransmitter:

Glutamate, On Switch




Major organ that breaks down drugs in the body:

Liver




Electrolyte imbalance commonly associated with psychotropic medication use:
Hyponatremia




The time needed to clear 50% if drugs from the plasma:

Half-life




The process of becoming desensitized and less responsive to a particular medication dose
overtime necessitating an increase:

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