NR 293 PHARMACOLOGY FOR NURSING PRACTICE]
COMPLETE EXAM QUESTIONS AND VERIFIED ANSWERS |
2026–2027 LATEST UPDATE | GUARANTEED PASS | DETAILED
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1. A nurse is reviewing the basic principles of pharmacology. Which term describes the movement
of a drug through the body from administration to elimination?
A. Pharmacodynamics
B. Pharmacotherapeutics
C. Pharmacokinetics
D. Toxicology
Correct Answer: C. Pharmacokinetics
Rationale:
Pharmacokinetics refers to absorption, distribution, metabolism, and excretion of drugs.
Pharmacodynamics focuses on drug effects on the body. Pharmacotherapeutics addresses clinical
use, while toxicology studies harmful effects.
2. A patient asks why two medications with different brand names appear to contain the same
drug. What is the nurse's best response?
A. Brand names indicate different active ingredients.
B. Generic drugs may be marketed under different brand names.
C. Generic drugs are less effective than brand-name drugs.
D. Brand names are assigned by healthcare providers.
Correct Answer: B. Generic drugs may be marketed under different brand names.
Rationale:
Many manufacturers market the same generic medication under different brand names. The active
ingredient remains the same, although inactive ingredients may vary.
3. Which route of administration generally provides the most rapid systemic drug effect?
A. Oral
B. Subcutaneous
C. Intramuscular
D. Intravenous
Correct Answer: D. Intravenous
Rationale:
Intravenous administration delivers medication directly into circulation, resulting in the fastest onset
of action. Other routes require absorption before reaching systemic circulation.
4. A nurse is preparing to administer a medication. Which action best reflects safe medication
practice?
,A. Administering medications prepared by another nurse
B. Verifying patient identity using two identifiers
C. Relying on room number for identification
D. Skipping allergy verification if previously documented
Correct Answer: B. Verifying patient identity using two identifiers
Rationale:
Using two patient identifiers is a core safety standard. Room numbers and assumptions increase risk
of medication errors.
5. Which organ is primarily responsible for drug metabolism?
A. Kidney
B. Liver
C. Lung
D. Pancreas
Correct Answer: B. Liver
Rationale:
The liver contains enzymes responsible for metabolizing many medications. The kidneys primarily
excrete drugs and metabolites.
6. A patient experiences dizziness after starting a new antihypertensive medication. This response
is classified as a(n):
A. Adverse effect
B. Allergic reaction
C. Idiosyncratic reaction
D. Medication error
Correct Answer: A. Adverse effect
Rationale:
Dizziness is a common adverse effect of many antihypertensives. An allergic reaction involves
immune-mediated symptoms such as rash or anaphylaxis.
7. Which factor is most likely to increase the risk of drug toxicity in older adults?
A. Increased liver size
B. Increased renal clearance
C. Decreased kidney function
D. Increased metabolism
Correct Answer: C. Decreased kidney function
Rationale:
Age-related declines in renal function may reduce drug elimination, increasing the risk of toxicity and
adverse effects.
8. A medication order reads "PO." What does this abbreviation indicate?
A. By injection
B. Topically
C. Sublingually
D. By mouth
, Correct Answer: D. By mouth
Rationale:
PO stands for "per os," meaning oral administration. It is one of the most common medication routes.
9. A nurse notes that a medication has a narrow therapeutic index. What does this indicate?
A. High safety margin
B. Minimal monitoring required
C. Small difference between effective and toxic doses
D. Drug is ineffective
Correct Answer: C. Small difference between effective and toxic doses
Rationale:
Medications with narrow therapeutic indexes require careful monitoring because toxicity can occur
close to therapeutic doses.
10. Which statement best describes pharmacodynamics?
A. Drug absorption and elimination
B. Drug movement through tissues
C. Drug storage in the body
D. Drug effects on the body
Correct Answer: D. Drug effects on the body
Rationale:
Pharmacodynamics focuses on how drugs interact with receptors and produce physiological effects.
11. A patient reports a history of severe penicillin allergy. What is the nurse's priority action before
administering medications?
A. Document the allergy and proceed
B. Verify all prescribed medications for potential cross-reactivity
C. Ask the patient if the allergy still exists
D. Delay all medications indefinitely
Correct Answer: B. Verify all prescribed medications for potential cross-reactivity
Rationale:
Medication review helps prevent administration of drugs that could trigger allergic reactions or cross-
sensitivity.
12. Which phase of pharmacokinetics occurs when a drug moves from the bloodstream into body
tissues?
A. Absorption
B. Metabolism
C. Distribution
D. Excretion
Correct Answer: C. Distribution
Rationale:
Distribution refers to the transport of a drug from circulation into tissues and organs where it exerts
effects.