1|Page
ATI PN PHARMACOLOGY CMS EXAM AND
PRACTICE EXAM NEWEST 2026/ 2027 TEST BANK|
CMS PN PHARMACOLOGY PROCTORED EXAM WITH
COMPLETE 550 REAL EXAM QUESTIONS AND
CORRECT VERIFIED ANSWERS/ ALREAD GRADED
A+ (MOST RECENT!!)
A client with severe acne is seen in the clinic and the health care
provider (HCP) prescribes isotretinoin. The nurse reviews the client's
medication record and would contact the (HCP) if the client is taking
which medication?
1. Vitamin A
2. Digoxin (Lanoxin)
3. Furosemide (Lasix)
4. Phenytoin (Dilantin) - Correct Answer - 1. Vitamin A
Isotretinoin is a metabolite of vitamin A and can produce generalized
intensification of isotretinoin toxicity. Because of the potential for
increased toxicity, vitamin A supplements should be discontinued before
isotretinoin therapy.
The nurse is applying a topical corticosteroid to a client with eczema.
The nurse would monitor for the potential for increased systemic
absorption of the medication if the medication were being applied to
which of the following body areas?
1. Back
2. Axilla
3. Soles of the feet
,2|Page
4. Palms of the hands - Correct Answer - 2. Axilla
Topical corticosteroids can be absorbed into the systemic circulation.
Absorption is higher from regions where the skin is especially
permeable (scalp, axilla, face, eyelids, neck, perineum, genitalia), and
lower from regions in which permeability is poor (back, palms, soles).
The clinic nurse is performing an admission assessment on a client. The
nurse notes that the client is taking azelaic acid (Azelex). Because of the
medication prescription, the nurse would suspect that the client is being
treated for:
1. Acne
2. Eczema
3. Hair loss
4. Herpes simplex - Correct Answer - 1. Acne
Azelaic acid is a topical medication used to treat mild to moderate acne.
The acid appears to work by suppressing the growth of
Propionibacterium acnes and decreasing the proliferation of
keratinocytes.
A nurse is caring for a client who is receiving an intravenous (IV)
infusion of an antineoplastic medication. During the infusion, the client
complains of pain at the insertion site. During an inspection of the site,
the nurse notes redness and swelling and that the rate of infusion of the
medication has slowed. The nurse should take which appropriate action?
1. Notify the registered nurse.
2. Administer pain medication to reduce the discomfort.
3. Apply ice and maintain the infusion rate, as prescribed.
4. Elevate the extremity of the IV site, and slow the infusion. - Correct
Answer - 1. Notify the registered nurse.
,3|Page
When antineoplastic medications (Chemotheraputic Agents) are
administered via IV, great care must be taken to prevent the medication
from escaping into the tissues surrounding the injection site, because
pain, tissue damage, and necrosis can result. The nurse monitors for
signs of extravasation, such as redness or swelling at the insertion site
and a decreased infusion rate. If extravasation occurs, the registered
nurse needs to be notified; he or she will then contact the health care
provider.
The client with squamous cell carcinoma of the larynx is receiving
bleomycin intravenously. The nurse caring for the client anticipates that
which diagnostic study will be prescribed?
1. Echocardiography
2. Electrocardiography
3. Cervical radiography
4. Pulmonary function studies - Correct Answer - 4. Pulmonary function
studies
Bleomycin is an antineoplastic medication (Chemotheraputic Agents)
that can cause interstitial pneumonitis, which can progress to pulmonary
fibrosis. Pulmonary function studies along with hematological, hepatic,
and renal function tests need to be monitored. The nurse needs to
monitor lung sounds for dyspnea and crackles, which indicate
pulmonary toxicity. The medication needs to be discontinued
immediately if pulmonary toxicity occurs.
The client with acute myelocytic leukemia is being treated with busulfan
(Myleran). Which laboratory value would the nurse specifically monitor
during treatment with this medication?
1. Clotting time
2. Uric acid level
, 4|Page
3. Potassium level
4. Blood glucose level - Correct Answer - 2. Uric acid level
Busulfan (Myleran) can cause an increase in the uric acid level.
Hyperuricemia can produce uric acid nephropathy, renal stones, and
acute renal failure.
The client with small cell lung cancer is being treated with etoposide
(VePesid). The nurse who is assisting in caring for the client during its
administration understands that which side effect is specifically
associated with this medication?
1. Alopecia
2. Chest pain
3. Pulmonary fibrosis
4. Orthostatic hypotension - Correct Answer - 4. Orthostatic
hypotension
A side effect specific to etoposide is orthostatic hypotension. The client's
blood pressure is monitored during the infusion. Hair loss occurs with
nearly all the antineoplastic medications. Chest pain and pulmonary
fibrosis are unrelated to this medication.
The nurse is reviewing the history and physical examination of a client
who will be receiving asparaginase (Elspar), an antineoplastic agent. The
nurse consults with the registered nurse regarding the administration of
the medication if which of the following is documented in the client's
history?
1. Pancreatitis
2. Diabetes mellitus
3. Myocardial infarction
ATI PN PHARMACOLOGY CMS EXAM AND
PRACTICE EXAM NEWEST 2026/ 2027 TEST BANK|
CMS PN PHARMACOLOGY PROCTORED EXAM WITH
COMPLETE 550 REAL EXAM QUESTIONS AND
CORRECT VERIFIED ANSWERS/ ALREAD GRADED
A+ (MOST RECENT!!)
A client with severe acne is seen in the clinic and the health care
provider (HCP) prescribes isotretinoin. The nurse reviews the client's
medication record and would contact the (HCP) if the client is taking
which medication?
1. Vitamin A
2. Digoxin (Lanoxin)
3. Furosemide (Lasix)
4. Phenytoin (Dilantin) - Correct Answer - 1. Vitamin A
Isotretinoin is a metabolite of vitamin A and can produce generalized
intensification of isotretinoin toxicity. Because of the potential for
increased toxicity, vitamin A supplements should be discontinued before
isotretinoin therapy.
The nurse is applying a topical corticosteroid to a client with eczema.
The nurse would monitor for the potential for increased systemic
absorption of the medication if the medication were being applied to
which of the following body areas?
1. Back
2. Axilla
3. Soles of the feet
,2|Page
4. Palms of the hands - Correct Answer - 2. Axilla
Topical corticosteroids can be absorbed into the systemic circulation.
Absorption is higher from regions where the skin is especially
permeable (scalp, axilla, face, eyelids, neck, perineum, genitalia), and
lower from regions in which permeability is poor (back, palms, soles).
The clinic nurse is performing an admission assessment on a client. The
nurse notes that the client is taking azelaic acid (Azelex). Because of the
medication prescription, the nurse would suspect that the client is being
treated for:
1. Acne
2. Eczema
3. Hair loss
4. Herpes simplex - Correct Answer - 1. Acne
Azelaic acid is a topical medication used to treat mild to moderate acne.
The acid appears to work by suppressing the growth of
Propionibacterium acnes and decreasing the proliferation of
keratinocytes.
A nurse is caring for a client who is receiving an intravenous (IV)
infusion of an antineoplastic medication. During the infusion, the client
complains of pain at the insertion site. During an inspection of the site,
the nurse notes redness and swelling and that the rate of infusion of the
medication has slowed. The nurse should take which appropriate action?
1. Notify the registered nurse.
2. Administer pain medication to reduce the discomfort.
3. Apply ice and maintain the infusion rate, as prescribed.
4. Elevate the extremity of the IV site, and slow the infusion. - Correct
Answer - 1. Notify the registered nurse.
,3|Page
When antineoplastic medications (Chemotheraputic Agents) are
administered via IV, great care must be taken to prevent the medication
from escaping into the tissues surrounding the injection site, because
pain, tissue damage, and necrosis can result. The nurse monitors for
signs of extravasation, such as redness or swelling at the insertion site
and a decreased infusion rate. If extravasation occurs, the registered
nurse needs to be notified; he or she will then contact the health care
provider.
The client with squamous cell carcinoma of the larynx is receiving
bleomycin intravenously. The nurse caring for the client anticipates that
which diagnostic study will be prescribed?
1. Echocardiography
2. Electrocardiography
3. Cervical radiography
4. Pulmonary function studies - Correct Answer - 4. Pulmonary function
studies
Bleomycin is an antineoplastic medication (Chemotheraputic Agents)
that can cause interstitial pneumonitis, which can progress to pulmonary
fibrosis. Pulmonary function studies along with hematological, hepatic,
and renal function tests need to be monitored. The nurse needs to
monitor lung sounds for dyspnea and crackles, which indicate
pulmonary toxicity. The medication needs to be discontinued
immediately if pulmonary toxicity occurs.
The client with acute myelocytic leukemia is being treated with busulfan
(Myleran). Which laboratory value would the nurse specifically monitor
during treatment with this medication?
1. Clotting time
2. Uric acid level
, 4|Page
3. Potassium level
4. Blood glucose level - Correct Answer - 2. Uric acid level
Busulfan (Myleran) can cause an increase in the uric acid level.
Hyperuricemia can produce uric acid nephropathy, renal stones, and
acute renal failure.
The client with small cell lung cancer is being treated with etoposide
(VePesid). The nurse who is assisting in caring for the client during its
administration understands that which side effect is specifically
associated with this medication?
1. Alopecia
2. Chest pain
3. Pulmonary fibrosis
4. Orthostatic hypotension - Correct Answer - 4. Orthostatic
hypotension
A side effect specific to etoposide is orthostatic hypotension. The client's
blood pressure is monitored during the infusion. Hair loss occurs with
nearly all the antineoplastic medications. Chest pain and pulmonary
fibrosis are unrelated to this medication.
The nurse is reviewing the history and physical examination of a client
who will be receiving asparaginase (Elspar), an antineoplastic agent. The
nurse consults with the registered nurse regarding the administration of
the medication if which of the following is documented in the client's
history?
1. Pancreatitis
2. Diabetes mellitus
3. Myocardial infarction
