MIDTERM EXAM REVIEW
/LATEST ADVANCED
PHARMACOLOGY FOR CARE OF
FAMILY|A GRADE 2026
Which non-amphetamines are FDA approved for weight loss that have
lower abuse risk? - ANSWER ✔✔Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss? -
ANSWER ✔✔-Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress
appetite by increasing the availability of norepinephrine at receptors in
the brain
,What is the maximum recommended duration of use for non-
amphetamines? - ANSWER ✔✔3 months or less
What drug schedule are Phentermine and Diethylpropion under? -
ANSWER ✔✔Schedule IV
What labs should be monitored with Phentermine and Diethylpropion?
What condition should we screen for? - ANSWER ✔✔-baseline CMP
(watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects - ANSWER ✔✔-increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? - ANSWER ✔✔Increases
satiety
What are some Phentermine/topiramate contraindications for use? -
ANSWER ✔✔not approved in children and contraindicated with
severe hepatic impairment
How should we educate patient to take Phentermine/topiramate to avoid
insomnia? - ANSWER ✔✔given before 1600
,What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution? - ANSWER ✔✔hx drug abuse,
glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects - ANSWER ✔✔insomnia,
nervousness, anxiety, depression, blurred vision
Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply. - ANSWER ✔✔A)
Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces
absorption of fat by 30%. - ANSWER ✔✔GI tract
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3
, Take multivitamin ___hours before/after to supplement fat-soluble
vitamins that may not be absorbed well when taking Orlistat. -
ANSWER ✔✔2
Orlistat is OTC as 60 mg TID with meals. Not approved in children
<____. - ANSWER ✔✔12
Orlistat results in the least amount of weight loss of all. How much? -
ANSWER ✔✔2-3% body weight (7 lbs in year)
Orlistat adverse effects - ANSWER ✔✔Fecal incontinence, oily rectal
leakage, flatus, abdominal cramps. liver damage (light-colored stools,
dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated? - ANSWER ✔✔In those with
malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking
Orlistat...especially if the patient is on coumadin? - ANSWER
✔✔Monitor Coumadin as Vitamin K deficiency may occur and intensify
effect of Coumadin.
A patient with a BMI of 27 would be considered: - ANSWER
✔✔overweight