BSNC 6000 FINAL Exam | Questions and
Answers with Verified Solutions | Latest
2026 Update
Question: What is hypersensitivity?
Answer:
A persons immune system reacts in a way that damages them rather than
protecting them
Question: What is type III hypersensitivity?
Answer:
Antigen-antibody complexes deposit into blood vessel walls causing
inflammation and tissue damage
Question: what cells produce antibody?
Answer:
plasma cells
Question: what is type 1 hypersensitivity?
Answer:
presence of IgE specific to an allergen
Question: what is the MOI of type 1 hypersensitivity?
Answer:
histamine stimulates mucus secretion in the nasal passages
and tears that leads to inflammation
,Question: what are examples of type 1 hypersensitivity?
Answer:
(atopic diseases) allergic reactions, asthma, dermatitis,
and anaphylaxis
Question: what is the immune mechanism of type II hypersensitivity?
Answer:
anti-body mediated immune reaction
where antibodies like IgG or IgM are directed against cells. This is an autoreactive antibody
that targets
its own tissues.
Question: What is the MOI of type II hypersensitivity?
Answer:
cellular destruction, functional loss, and tissue damage d/t
antibodies targeting the body.
Question: examples of type II hypersensitivity and where are they commonly seen
Answer:
autoimmune diseases,
infections, cytopenias, and hemolytic anemias. seen in transplants and blood transfusions.
Question: What is the immune mechanism of type III hypersensitivity?
Answer:
mediated by immune complexes like
antigen-antibody (IgG) complexes accumulating in the body.
,Question: which type of hypersensitivity is most complex?
Answer:
type III
Question: What is the MOI for type III hypersensitivity?
Answer:
antigen-antibody complexes deposited in blood vessel
walls cause inflammation and tissue damage where the complexes accumulate.
Question: Common examples of type III hypersensitivity
Answer:
SLE (Lupus) and RA (rheumatoid arthritis)
Question: What is the immune mechanism of type IV hypersensitivity?
Answer:
autoreactive cytotoxic cells
Question: what is the MOI in type IV hypersensitivity?
Answer:
autoreactive cytotoxic cells attack the bodies own tissues
especially i the lungs and airways.
Question: common examples of type IV hypersensitivity
Answer:
HIV, RSV, contact dermatitis, TB, MS, and DM1
, Question: why is lupus rare?
Answer:
because it requires a series of complex events that need to occur over many years.
Question: steps for lupus to occur?
Answer:
genetic predisposition --> macrophage challenging event (covid) -->
unregulated apoptosis of macrophages --> build up of debris in the body causes the making of
antibodies --> immune system is now compromised --> we make antibodies against ourself
Question: what do macrophages do?
Answer:
after infection they clean up debris in the tissue and release cytokines to
signal tissue repair
Question: true or false: macrophage function is a spectrum
Answer:
true, some people have hypoactive and some
hyperactive
Question: what is an example of a trigger that challenges the macrophages
Answer:
hydralazine, a type of vasodilator
Question: common events that lead to flare ups
Answer:
pregnancy (stiulates antibody production) and UV light (sun
stimulates immune response)
Answers with Verified Solutions | Latest
2026 Update
Question: What is hypersensitivity?
Answer:
A persons immune system reacts in a way that damages them rather than
protecting them
Question: What is type III hypersensitivity?
Answer:
Antigen-antibody complexes deposit into blood vessel walls causing
inflammation and tissue damage
Question: what cells produce antibody?
Answer:
plasma cells
Question: what is type 1 hypersensitivity?
Answer:
presence of IgE specific to an allergen
Question: what is the MOI of type 1 hypersensitivity?
Answer:
histamine stimulates mucus secretion in the nasal passages
and tears that leads to inflammation
,Question: what are examples of type 1 hypersensitivity?
Answer:
(atopic diseases) allergic reactions, asthma, dermatitis,
and anaphylaxis
Question: what is the immune mechanism of type II hypersensitivity?
Answer:
anti-body mediated immune reaction
where antibodies like IgG or IgM are directed against cells. This is an autoreactive antibody
that targets
its own tissues.
Question: What is the MOI of type II hypersensitivity?
Answer:
cellular destruction, functional loss, and tissue damage d/t
antibodies targeting the body.
Question: examples of type II hypersensitivity and where are they commonly seen
Answer:
autoimmune diseases,
infections, cytopenias, and hemolytic anemias. seen in transplants and blood transfusions.
Question: What is the immune mechanism of type III hypersensitivity?
Answer:
mediated by immune complexes like
antigen-antibody (IgG) complexes accumulating in the body.
,Question: which type of hypersensitivity is most complex?
Answer:
type III
Question: What is the MOI for type III hypersensitivity?
Answer:
antigen-antibody complexes deposited in blood vessel
walls cause inflammation and tissue damage where the complexes accumulate.
Question: Common examples of type III hypersensitivity
Answer:
SLE (Lupus) and RA (rheumatoid arthritis)
Question: What is the immune mechanism of type IV hypersensitivity?
Answer:
autoreactive cytotoxic cells
Question: what is the MOI in type IV hypersensitivity?
Answer:
autoreactive cytotoxic cells attack the bodies own tissues
especially i the lungs and airways.
Question: common examples of type IV hypersensitivity
Answer:
HIV, RSV, contact dermatitis, TB, MS, and DM1
, Question: why is lupus rare?
Answer:
because it requires a series of complex events that need to occur over many years.
Question: steps for lupus to occur?
Answer:
genetic predisposition --> macrophage challenging event (covid) -->
unregulated apoptosis of macrophages --> build up of debris in the body causes the making of
antibodies --> immune system is now compromised --> we make antibodies against ourself
Question: what do macrophages do?
Answer:
after infection they clean up debris in the tissue and release cytokines to
signal tissue repair
Question: true or false: macrophage function is a spectrum
Answer:
true, some people have hypoactive and some
hyperactive
Question: what is an example of a trigger that challenges the macrophages
Answer:
hydralazine, a type of vasodilator
Question: common events that lead to flare ups
Answer:
pregnancy (stiulates antibody production) and UV light (sun
stimulates immune response)
