N521: Pharmacology – ANS Exam Questions With Complete Answers

N521: Pharmacology – ANS Exam Questions
With Complete Answers

Neurotransmitters: - ANSWER Ach:
- Released at cholinergic receptor
- Receptors that bind: nicotinic, muscarinic
- Degraded by enzyme AchE
NE:
- Degraded by MAO

Alpha 1 Function - ANSWER Vasoconstriction
↑ peripheral resistance
↓ bladder

alpha 2 function - ANSWER ↓ NE release
↓ insulin

Beta 1 function - ANSWER ↑ Renin
↑ Heart Rate/force of contraction

Beta 2 function - ANSWER Vascodialation
bronchodilation

Selectivity - ANSWER Drugs binding to certain receptors

Direct acting - ANSWER - (drug) Directly binds to receptor
- Rest and digest response

Indirect acting - ANSWER - Attaches to AchE degrader
- Ach cant degrade
- Enhanced rest and digest response

Xerostomia - ANSWER dry mouth

reflex tachycardia - ANSWER temporary increase in heart rate that occurs when
blood pressure falls

Cholinergic agonist general info: - ANSWER - Can be direct or indirect acting
- Meant to ↑PSNS response

Cholinergic agonist cardiac effects - ANSWER Bradycardia

, Hypotension
Atrial fibrillation

cholinergic agonist adverse effects - ANSWER blurred vision
shortness of breath
Urination frequently
nausea and vomiting

cholinergic agonist contraindications - ANSWER reflect tachycardia
urinary/bowel obstruction
Asthma
COPD

cholinergic agonist nursing diagnosis - ANSWER urinary retention

uses and SE for direct acting cholinergic agonists - ANSWER Urinary retention

↓HR
Vasodialation
Bronchoconstriction
↑ GI
↑ urination

Uses and SE for anticholinesterase - ANSWER Myasthenia gravis
Alzheimers
Antidotes (gas poisioning)
glaucoma

↑ memory
↑ muscle contractions

AchE inhibitor - ANSWER Don't destroy achE
Non-selective

cholinergic crisis and symptoms - ANSWER Overdose of AchE

Symptoms:
Nausea
Vomiting
Twitching
Muscle weakness

muscarinic antagonist general info - ANSWER - PSNS blocking
- Ach blocked at muscarinic receptors
- ↑ SNS